Mungoven TJ, Henderson LA, Meylakh N. Chronic migraine pathophysiology and treatment: a review of current perspectives. Front Pain Res 2021, 2. https://doi.org/10.3389/fpain.2021.705276

Amiri P, Kazeminasab S, Nejadghaderi SA, Mohammadinasab R, Pourfathi H, Araj-Khodaei M, Sullman MJM, Kolahi AA, Safiri S. Migraine: a review on its history, Global Epidemiology, risk factors, and comorbidities. Front Neurol. 2021;12:800605.

Article  PubMed  Google Scholar 

Vetvik KG, MacGregor EA. Sex differences in the epidemiology, clinical features, and pathophysiology of migraine. Lancet Neurol. 2017;16(1):76–87.

Article  CAS  PubMed  Google Scholar 

Hautakangas H, Winsvold BS, Ruotsalainen SE, Bjornsdottir G, Harder AVE, Kogelman LJA, Thomas LF, Noordam R, Benner C, Gormley P, et al. Genome-wide analysis of 102,084 migraine cases identifies 123 risk loci and subtype-specific risk alleles. Nat Genet. 2022;54(2):152–60.

Article  CAS  PubMed  PubMed Central  Google Scholar 

Anttila V, Winsvold BS, Gormley P, Kurth T, Bettella F, McMahon G, Kallela M, Malik R, de Vries B, Terwindt G, et al. Genome-wide meta-analysis identifies new susceptibility loci for migraine. Nat Genet. 2013;45(8):912–7.

Article  CAS  PubMed  PubMed Central  Google Scholar 

Friedman DI, De ver Dye T. Migraine and the environment. Headache. 2009;49(6):941–52.

Article  PubMed  Google Scholar 

Goadsby PJ. Pathophysiology of migraine. Ann Indian Acad Neurol. 2012;15(Suppl 1):S15–22.

Article  PubMed  PubMed Central  Google Scholar 

Sundermann EE, Maki PM, Bishop JR. A review of estrogen receptor alpha gene (ESR1) polymorphisms, mood, and cognition. Menopause. 2010;17(4):874–86.

Article  PubMed  PubMed Central  Google Scholar 

Schürks M, Rist PM, Kurth T. Sex hormone receptor gene polymorphisms and migraine: a systematic review and meta-analysis. Cephalalgia. 2010;30(11):1306–28.

Article  PubMed  PubMed Central  Google Scholar 

Clegg DJ, Palmer BF. Effects of an estrogen receptor α variant. N Engl J Med. 2013;369(17):1663–4.

Article  CAS  PubMed  PubMed Central  Google Scholar 

Tan SC, Low TY, Mohamad Hanif EA, Sharzehan MAK, Kord-Varkaneh H, Islam MA. The rs9340799 polymorphism of the estrogen receptor alpha (ESR1) gene and its association with breast cancer susceptibility. Sci Rep. 2021;11(1):18619.

Article  CAS  PubMed  PubMed Central  Google Scholar 

An X, Fang J, Lin Q, Lu C, Ma Q, Qu H. New evidence for involvement of ESR1 gene in susceptibility to Chinese migraine. J Neurol. 2017;264:81–7.

Article  PubMed  Google Scholar 

Colson NJ, Lea RA, Quinlan S, Griffiths LR. No role for estrogen receptor 1 gene intron 1 pvu II and exon 4 C325G polymorphisms in migraine susceptibility. BMC Med Genet. 2006;7:1–6.

Article  Google Scholar 

Colson NJ, Lea RA, Quinlan S, MacMillan J, Griffiths LR. The estrogen receptor 1 G594A polymorphism is associated with migraine susceptibility in two independent case/control groups. Neurogenetics. 2004;5:129–33.

Article  CAS  PubMed  Google Scholar 

Corominas R, Ribases M, Cuenca-Leon E, Cormand B, Macaya A. Lack of association of hormone receptor polymorphisms with migraine. Eur J Neurol. 2009;16(3):413–5.

Article  CAS  PubMed  Google Scholar 

Coşkun S, YÜcel Y, Çim A, Cengiz B, Oztuzcu S, Varol S, Özdemir HH, Uzar E. Contribution of polymorphisms in ESR1, ESR2, FSHR, CYP19A1, SHBG and NRIP1 genes to migraine susceptibility in Turkish population. J Genet. 2016;95:131–40.

Article  PubMed  Google Scholar 

Ghosh J, Joshi G, Pradhan S, Mittal B. Potential role of aromatase over estrogen receptor gene polymorphisms in migraine susceptibility: a case control study from North India. PLoS ONE. 2012;7(4):e34828.

Article  CAS  PubMed  PubMed Central  Google Scholar 

Joshi G, Pradhan S, Mittal B. Role of the oestrogen receptor (ESR1 PvuII and ESR1 325 C→ G) and progesterone receptor (PROGINS) polymorphisms in genetic susceptibility to migraine in a north Indian population. Cephalalgia. 2010;30(3):311–20.

Article  CAS  PubMed  Google Scholar 

Kaunisto M, Kallela M, Hämäläinen E, Kilpikari R, Havanka H, Harno H, Nissilä M, Säkö E, Ilmavirta M, Liukkonen J. Testing of variants of the MTHFR and ESR1 genes in 1798 Finnish individuals fails to confirm the association with migraine with aura. Cephalalgia. 2006;26(12):1462–72.

Article  CAS  PubMed  Google Scholar 

Kumar S, Raina JK, Sudershan A, Mahajan K, Jasrotia R, Maharana C, Panjalia RK, Kumar P. An Association Study of ESR 1–Xba I and Pvu II Gene Polymorphism in Migraine susceptibility in the Jammu Region. Eur Neurol. 2023;86(1):55–62.

Article  CAS  PubMed  Google Scholar 

Oterino A, Pascual J, de Alegría CR, Valle N, Castillo J, Bravo Y, González F, Sánchez-Velasco P, Cayón A. Leyva-Cobián F: Association of migraine and ESR1 G325C polymorphism. NeuroReport. 2006;17(1):61–4.

Article  CAS  PubMed  Google Scholar 

Oterino A, Toriello M, Cayón A, Castillo J, Colas R, Alonson-Arranz A, Ruiz‐Alegria C, Quintela E, Monton F, Ruiz‐Lavilla N. Multilocus analyses reveal involvement of the ESR1, ESR2, and FSHR genes in migraine. Headache: J Head Face Pain. 2008;48(10):1438–50.

Article  Google Scholar 

Page MJ, McKenzie JE, Bossuyt PM, Boutron I, Hoffmann TC, Mulrow CD, Shamseer L, Tetzlaff JM, Akl EA, Brennan SE. The PRISMA 2020 statement: an updated guideline for reporting systematic reviews. Int J Surg. 2021;88:105906.

Article  PubMed  Google Scholar 

Wells GA, Shea B, O’Connell D, Peterson J, Welch V, Losos M, Tugwell P. The Newcastle-Ottawa Scale (NOS) for assessing the quality of nonrandomised studies in meta-analyses. 2000. https://web.archive.org/web/20210716121605id_/http://www3.med.unipmn.it/dispense_ebm/2009-2010/Corso%20Perfezionamento%20EBM_Faggiano/NOS_oxford.pdf

Faul F, Erdfelder E, Buchner A, Lang A-G. Statistical power analyses using G* power 3.1: tests for correlation and regression analyses. Behav Res Methods. 2009;41(4):1149–60.

Article  PubMed  Google Scholar 

Lee YH. Meta-analysis of genetic association studies. Annals Lab Med. 2015;35(3):283.

Article  CAS  Google Scholar 

Egger M, Smith GD, Schneider M, Minder C. Bias in meta-analysis detected by a simple, graphical test. BMJ. 1997;315(7109):629–34.

Article  CAS  PubMed  PubMed Central  Google Scholar 

Melsen W, Bootsma M, Rovers M, Bonten M. The effects of clinical and statistical heterogeneity on the predictive values of results from meta-analyses. Clin Microbiol Infect. 2014;20(2):123–9.

Article  CAS  PubMed  Google Scholar 

Wetterslev J, Jakobsen JC, Gluud C. Trial Sequential Analysis in systematic reviews with meta-analysis. BMC Med Res Methodol. 2017;17(1):39.

Article  PubMed  PubMed Central  Google Scholar 

Wetterslev J, Jakobsen JC, Gluud C. Trial sequential analysis in systematic reviews with meta-analysis. BMC Med Res Methodol. 2017;17(1):1–18.

Article  Google Scholar 

Wetterslev J, Thorlund K, Brok J, Gluud C. Trial sequential analysis may establish when firm evidence is reached in cumulative meta-analysis. J Clin Epidemiol. 2008;61(1):64–75.

Article  PubMed  Google Scholar 

Alonso P, Gratacòs M, Segalàs C, Escaramís G, Real E, Bayés M, Labad J, Pertusa A, Vallejo J, Estivill X, et al. Variants in estrogen receptor alpha gene are associated with phenotypical expression of obsessive-compulsive disorder. Psychoneuroendocrinology. 2011;36(4):473–83.

Article  CAS  PubMed  Google Scholar 

Bianchin MM, Londero RG, Lima JE, Bigal ME. Migraine and epilepsy: a focus on overlapping clinical, pathophysiological, molecular, and therapeutic aspects. Curr Pain Headache Rep. 2010;14:276–83.

Article