Bray F, Laversanne M, Sung H, Ferlay J, Siegel RL, Soerjomataram I, Jemal A (2024) Global cancer statistics 2022: GLOBOCAN estimates of incidence and mortality worldwide for 36 cancers in 185 countries. CA Cancer J Clin 74(3):229–263. https://doi.org/10.3322/caac.21834

Article  PubMed  Google Scholar 

Board WC of TE (2020) Soft tissue and bone tumours. WHO Classification of Tumours

Looser KG, Shah JP, Strong EW (1978) The significance of ‘positive’ margins in surgically resected epidermoid carcinomas. Head Neck Surg 1:107–111

Article  CAS  PubMed  Google Scholar 

Kovacs AF (2004) Relevance of positive margins in case of adjuvant therapy of oral cancer. Int J Oral Maxillofac Surg 33:447–453

Article  CAS  PubMed  Google Scholar 

Vikram B, Strong EW, Shah JP et al (1984) Failure at the primary site following multimodality treatment in advanced head and neck cancer. Head Neck Surg 6:720–723

Article  CAS  PubMed  Google Scholar 

Loree TR, Strong EW (1990) Significance of positive margins in oral cavity squamous carcinoma. Am J Surg 160:410–414

Article  CAS  PubMed  Google Scholar 

Ravasz LA, Slootweg PJ, Hordijk GJ et al (1991) The status of the resection margin as a prognostic factor in the treatment of head and neck carcinoma. J Craniomaxillofac Surg 19:314–318

Article  CAS  PubMed  Google Scholar 

Cook JA, Jones AS, Phillips DE et al (1993) Implications of tumor in resection margins following surgical treatment of squamous cell carcinoma of the head and neck. Clin Otolaryngol 18:37–41

Article  CAS  PubMed  Google Scholar 

Slootweg PJ, Hordijk GJ, Schade Y et al (2002) Treatment failure and margin status in head and neck cancer. A critical view on the potential value of molecular pathology. Oral Oncol 38:500–503

Article  PubMed  Google Scholar 

Johnson RE, Sigman JD, Funk GF et al (1997) Quantification of surgical margin shrinkage in the oral cavity. Head Neck 19:281–286

Article  CAS  PubMed  Google Scholar 

Mistry RC, Qureshi SS, Kumaran C (2005) Post-resection mucosal margin shrinkage in oral cancer: quantification and significance. J Surg Oncol 91(2):131–133. https://doi.org/10.1002/jso.20285

Article  PubMed  Google Scholar 

Cheng A, Cox D, Schmidt BL (2008) Oral squamous cell carcinoma margin discrepancy after resection and pathologic processing. J Oral Maxillofac Surg 66(3):523–529. https://doi.org/10.1016/j.joms.2007.08.040

Article  PubMed  Google Scholar 

Egemen O, Bingöl D, Orman Ç, Sayilgan AT, Özkaya Ö, Akan M (2014) Quantification of the surgical margin shrinkage in lip cancer: determining the relation between the surgical and histopathologic margins. J Craniofac Surg 25(6):2152–2155. https://doi.org/10.1097/SCS.0000000000001150

Article  PubMed  Google Scholar 

El-Fol HA, Noman SA, Beheiri MG, Khalil AM, Kamel MM (2015) Significance of post-resection tissue shrinkage on surgical margins of oral squamous cell carcinoma. J Craniomaxillofac Surg 43(4):475–482. https://doi.org/10.1016/j.jcms.2015.01.009

Article  PubMed  Google Scholar 

Umstattd LA, Mills JC, Critchlow WA, Renner GJ, Zitsch RP 3rd (2017) Shrinkage in oral squamous cell carcinoma: an analysis of tumor and margin measurements in vivo, post-resection, and post-formalin fixation. Am J Otolaryngol 38(6):660–662. https://doi.org/10.1016/j.amjoto.2017.08.011

Article  PubMed  Google Scholar 

Burns C, Gorina FM (2021) An analysis of tumor margin shrinkage in the surgical resection of squamous cell carcinoma of the oral cavity. Cureus 13(5):e15329. https://doi.org/10.7759/cureus.15329

Article  PubMed  PubMed Central  Google Scholar 

Al-Sabaawy HB, Rahawi AM, Al-Mahmood SS (2021) Standard techniques for formalin-fixed paraffin-embedded tissue: a pathologist’s perspective. Iraqi J Vet Sci 35(Supplement I-III):127–135. https://doi.org/10.33899/ijvs.2021.131918.2023

Article  Google Scholar 

Pangare TB, Waknis PP, Bawane SS, Patil MN, Wadhera S, Patowary PB (2017) Effect of formalin fixation on surgical margins in patients with oral squamous cell carcinoma. J Oral Maxillofac Surg 75(6):1293–1298. https://doi.org/10.1016/j.joms.2016.11.024

Article  PubMed  Google Scholar 

Solomon J, Hinther A, Matthews TW, Nakoneshny SC, Hart R, Dort JC, Chandarana SP (2021) The impact of close surgical margins on recurrence in oral squamous cell carcinoma. J Otolaryngol Head Neck Surg 50(1):9. https://doi.org/10.1186/s40463-020-00483-w

Article  PubMed  PubMed Central  Google Scholar 

Fowler J, Campanile Y, Warner A, Laxague F, Fnais N, Fung K, Mendez A, MacNeil D, Yoo J, Palma D, Nichols A (2022) Surgical margins of the oral cavity: is 5 mm really necessary? J Otolaryngol Head Neck Surg 51(1):38. https://doi.org/10.1186/s40463-022-00584-8

Article  PubMed  PubMed Central  Google Scholar