Jason L Stein is an Associate Professor in the Department of Genetics and UNC Neuroscience Center at the University of North Carolina at Chapel Hill. Dr. Stein’s lab explores how genetic variation influences brain structure, function, and risk for neuropsychiatric disorders. Dr. Stein co-founded and co-led the first international consortium to discover the specific genetic variants affecting gross brain structure in the living human brain measured via MRI: the Enhancing Neuroimaging Genetics through Meta-analysis (ENIGMA) consortium. His lab’s work annotated the evolutionary relevance of those genetic variants associated with cortical structure. Dr. Stein’s lab also models the effect of genetic variation in human neural progenitor cells and iPSC-derived cortical organoids through cell-type specific expression quantitative trait loci (QTL) and chromatin accessibility QTL analyses, both in stimulated and unstimulated states, explaining new mechanisms underlying risk for neuropsychiatric disorders.