Conceptualization: Mingyang Sun, MD; Xiaoling Wang, PhD; Methodology: Zhongyuan Lu, PhD; Yitian Yang, MD, PhD; Software: Suang Lv, MD; Mengrong Miao, MD; Validation: Wan-Ming Chen, PhD; Szu-Yuan Wu, MD, MPH, PhD; Formal Analysis: Jiaqiang Zhang, MD, PhD; Xiaoling Wang, PhD; Investigation: Yitian Yang, MD, PhD; Zhongyuan Lu, PhD; Resources: Mengrong Miao, MD; Wan-Ming Chen, PhD; Data Curation: Suang Lv, MD; Mingyang Sun, MD; Writing - Original Draft: Jiaqiang Zhang, MD, PhD; Szu-Yuan Wu, MD,