Functional genomics refers to molecular biological approaches examining the interactions and roles of genes and genomes in protein functions and which can include genomics and epigenomics, transcriptomics, proteomics and metabolomics. Diverse applications include pathophysiology, drug discovery, agriculture and livestock improvement (Goh et al., 2018). Transgenic animals enable investigation of gene function, disease mechanisms, and therapeutic intervention (Casey and Stewart, 2020, Jaenisch,