Krogmann A, Peters L, von Hardenberg L, et al. Keeping up with the therapeutic advances in schizophrenia: a review of novel and emerging pharmacological entities. CNS Spectr. 2019;24:38–69.
Doknic M, Maric NP, Britvic D, et al. Bone remodeling, bone mass and weight gain in patients with stabilized schizophrenia in real-life conditions treated with long-acting injectable risperidone. Neuroendocrinology. 2011;94(3):246–54.
Article PubMed CAS Google Scholar
Kishimoto T, Watanabe K, Shimada N, et al. Antipsychotic-induced hyperprolactinemia inhibits the hypothalamo-pituitary-gonadal axis and reduces bone mineral density in male patients with schizophrenia. J Clin Psychiatry. 2008;69(3):385–91.
Article PubMed CAS Google Scholar
Melmed S, Casanueva FF, Hoffman AR, et al. Diagnosis and treatment of hyperprolactinemia: an endocrine society clinical practice guideline. J Clin Endocrinol Metab. 2011;96(2):273–88.
Article PubMed CAS Google Scholar
Milano W, Colletti C, Capasso A. Hyperprolactinemia induced by antipsychotics: from diagnosis to treatment approach. Endocr Metab Immune Disord. 2017;17(1):38–55.
Takechi K, Yoshioka Y, Kawazoe H, et al. Psychiatric patients with antipsychotic drug-induced hyperprolactinemia and menstruation disorders. Biol Pharm Bull. 2017;40(10):1775–8.
Article PubMed CAS Google Scholar
Wieck A, Haddad P. Hyperprolactinaemia caused by antipsychotic drugs. BMJ (Clin Res Ed). 2002;324(7332):250–2.
Bushe C, Shaw M, Peveler R. A review of the association between antipsychotic use and hyperprolactinaemia. J Psychopharmacol (Oxf, Engl). 2008;22:46–55.
Besnard I, Auclair V, Callery G, et al. Hyperprolactinémies induites par les antipsychotiques : physiopathologie, clinique et surveillance. Encephale. 2014;40(1):86–94.
Article PubMed CAS Google Scholar
Leucht S, Cipriani A, Spineli L, et al. Comparative efficacy and tolerability of 15 antipsychotic drugs in schizophrenia: a multiple-treatments meta-analysis. Lancet. 2013;382(9896):951–62.
Article PubMed CAS Google Scholar
Huhn M, Nikolakopoulou A, Schneider-Thoma J, et al. Comparative efficacy and tolerability of 32 oral antipsychotics for the acute treatment of adults with multi-episode schizophrenia: a systematic review and network meta-analysis. Lancet. 2019;394(10202):939–51.
Article PubMed PubMed Central CAS Google Scholar
Zhu Y, Zhang C, Siafis S, et al. Prolactin levels influenced by antipsychotic drugs in schizophrenia: a systematic review and network meta-analysis. Schizophr Res. 2021;237:20–5.
Article PubMed CAS Google Scholar
Kishimoto T, Hagi K, Nitta M, et al. Long-term effectiveness of oral second-generation antipsychotics in patients with schizophrenia and related disorders: a systematic review and meta-analysis of direct head-to-head comparisons. World Psychiatry. 2019;18(2):208–24.
Article PubMed PubMed Central Google Scholar
Wallach JD, Sullivan PG, Trepanowski JF, et al. Sex based subgroup differences in randomized controlled trials: empirical evidence from cochrane meta-analyses. BMJ (Clin Res Ed). 2016;355: i5826.
Peveler RC, Branford D, Citrome L, et al. Antipsychotics and hyperprolactinaemia: clinical recommendations. J Psychopharmacol. 2008. https://doi.org/10.1177/0269881107087346.
Hasan A, Falkai P, Wobrock T, et al. World federation of societies of biological psychiatry (wfsbp) guidelines for biological treatment of schizophrenia, part 1: Update 2012 on the acute treatment of schizophrenia and the management of treatment resistance. World J Biol Psychiatry. 2012;13(5):318–78.
Leucht S, Samara M, Heres S, et al. Dose equivalents for antipsychotic drugs: the DDD method. Schizophr Bull. 2016;42(Suppl 1):S90–4.
Article PubMed PubMed Central Google Scholar
Luykx JJ, Correll CU, Manu P, et al. Pneumonia risk, antipsychotic dosing, and anticholinergic burden in schizophrenia. JAMA Psychiatr. 2024;81(10):967–75.
Taipale H, Tanskanen A, Correll CU, et al. Real-world effectiveness of antipsychotic doses for relapse prevention in patients with first-episode schizophrenia in Finland: a nationwide, register-based cohort study. Lancet Psychiatry. 2022;9(4):271–9.
Montejo ÁL, Arango C, Bernardo M, et al. Multidisciplinary consensus on the therapeutic recommendations for iatrogenic hyperprolactinemia secondary to antipsychotics. Front Neuroendocrinol. 2017;45:25–34.
Article PubMed CAS Google Scholar
Serri O, Chik CL, Ur E, et al. Diagnosis and management of hyperprolactinemia. CMAJ Can Med Assoc J. 2003;169(6):575–81.
Peuskens J, Pani L, Detraux J, et al. The effects of novel and newly approved antipsychotics on serum prolactin levels: a comprehensive review. CNS Drugs. 2014;28(5):421–53.
PubMed PubMed Central CAS Google Scholar
Lichtenstein P, Halldner L, Zetterqvist J, et al. Medication for attention deficit-hyperactivity disorder and criminality. N Engl J Med. 2012;367(21):2006–14.
Article PubMed PubMed Central CAS Google Scholar
Taipale H, Tanskanen A, Mehtälä J, et al. 20-year follow-up study of physical morbidity and mortality in relationship to antipsychotic treatment in a nationwide cohort of 62,250 patients with schizophrenia (fin20). World Psychiatry. 2020;19(1):61–8.
Article PubMed PubMed Central Google Scholar
Roth AJ. Multiple comparison procedures for discrete test statistics. J Stat Plann Inference. 1999;82(1–2):101–17.
Fitzgerald P, Dinan TG. Prolactin and dopamine: what is the connection? A review article. J Psychopharmacol (Oxf, Engl). 2008;22(2 Suppl):12–9.
Komossa K, Rummel-Kluge C, Schmid F, et al. Quetiapine versus other atypical antipsychotics for schizophrenia. Cochrane Database Syst Rev. 2010;(1):CD006625. https://doi.org/10.1002/14651858.CD006625.pub2.
Haddad PM, Wieck A. Antipsychotic-induced hyperprolactinaemia: mechanisms, clinical features and management. Drugs. 2004;64(20):2291–314.
Article PubMed CAS Google Scholar
Riedel M, Müller N, Strassnig M, et al. Quetiapine has equivalent efficacy and superior tolerability to risperidone in the treatment of schizophrenia with predominantly negative symptoms. Eur Arch Psychiatry Clin Neurosci. 2005;255(6):432–7.
Kelly DL, Conley RR. A randomized double-blind 12-week study of quetiapine, risperidone or fluphenazine on sexual functioning in people with schizophrenia. Psychoneuroendocrinology. 2006;31(3):340–6.
Article PubMed CAS Google Scholar
Citrome L. Drug safety evaluation of ziprasidone. Expert Opin Drug Saf. 2011;10(3):437–48.
Article PubMed CAS Google Scholar
Galbally M, Wynter K, Siskind D, et al. Sex differences between female and male individuals in antipsychotic efficacy and adverse effects in the treatment of schizophrenia. CNS Drugs. 2024;38(7):559–70.
Article PubMed PubMed Central CAS Google Scholar
Melkersson KI, Hulting AL, Rane AJ. Dose requirement and prolactin elevation of antipsychotics in male and female patients with schizophrenia or related psychoses. Br J Clin Pharmacol. 2001;51(4):317–24.
Article PubMed PubMed Central CAS Google Scholar
Retief M, Chiliza B, Phahladira L, et al. Prolactin, flupenthixol decanoate and first episode schizophrenia—clinical and laboratory correlates. Metab Brain Dis. 2019;34(6):1679–87.
Article PubMed CAS Google Scholar
Grigg J, Worsley R, Thew C, et al. Antipsychotic-induced hyperprolactinemia: synthesis of world-wide guidelines and integrated recommendations for assessment, management and future research. Psychopha
Comments (0)