Chondrocalcinosis, defined as the radiographic evidence of calcium pyrophosphate dihydrate (CPPD) crystal deposition within joint structures, often presents variably, ranging from asymptomatic forms to overt clinical manifestations. Radiofrequency Echographic Multi Spectrometry (REMS) is an advanced imaging modality traditionally employed for assessing bone mineral density (BMD), but it also exhibits potential in identifying incidental findings suggestive of crystal arthropathies such as chondrocalcinosis. This report presents a case of a 65-year-old female patient with a history of a vertebral fracture, in which REMS detected calcifications consistent with chondrocalcinosis, subsequently verified by conventional radiography. This case underscores the dual utility of REMS in both osteoporosis evaluation and as an ancillary tool for recognizing signs of CPPD deposition. Further research is necessary to delineate the broader implications of REMS in diagnosing and managing chondrocalcinosis.