Author links open overlay panel, , , , , , , , Highlights•This is a nationwide real-world survey.
•CL is associated with improved QoL among parents compared to other treatments.
•QoL improved only when CL was compared to open-loop systems in children.
•CL decreased the time parents spend managing diabetes, but not for the children.
•CL did not improve anxiety or sleep quality.
•Socioeconomic factors and diabetes-related events influence QoL.
AbstractAimTo conduct a population-based study on the quality of life (QoL) in families (mothers, fathers, and children) of children using closed loop (CL) compared to those using multiple daily injections (MDI), open loop (OL), and low glucose suspend (LGS) systems.
MethodsA nationwide French survey of children with type 1 diabetes (T1D) and their parents was conducted through the national family association, Familles AJD, in 2024. Six validated questionnaires were used for assessing QoL, anxiety, time spent managing diabetes, and sleep quality. Multivariate analyses were performed.
ResultsWe collected 1593 surveys (1093 from mothers, 242 from fathers, and 258 from children > 8 years). T1D children were aged 11.3 ± 4 years, had diabetes for 4.7 ± 3.8 years; 18% used MDI, 41% OL, 13% LGS, and 29% CL. HbA1c was 7.3 ± 0.6% with CL, vs. 7.7 ± 1.0% for other treatments (P < 0.05). CL was associated with improved QoL scores in parents (compared to OL and MDI), and children (compared to OL, not MDI). Time spent managing diabetes was lower with CL in parents, not children. Anxiety and sleep quality were not improved with CL. Child age (in parents) and household income (in all) were associated with improved QoL. HbA1c and a history of ketoacidosis (in mothers), or a history of severe hypoglycemia (in children), had a deleterious effect. Mothers experienced lower QoL, but scores correlated within the household.
ConclusionCL enhanced the QoL in families of children with T1D. Socioeconomic factors and diabetes-related events influence QoL differently depending on the respondent group.
KeywordsChild
Closed loop
Multiple daily injections
Quality of life, anxiety
Type 1 diabetes mellitus
© 2025 The Author(s). Published by Elsevier Masson SAS.
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