Addressing the social determinants of adverse outcomes in pregestational diabetes

ElsevierVolume 39, Issue 6, December 2025, 102050Best Practice & Research Clinical Endocrinology & MetabolismAuthor links open overlay panel, , , ,

Diabetes is among the most prevalent chronic diseases worldwide, with incidence rising each year, shaped by social inequities which influence both vulnerability to disease and access to quality care. These inequities and their systemic drivers are collectively termed the Social Determinants of Health (SDOH). Pregnancy introduces additional physiological and social challenges that can intensify existing inequities. For individuals with diabetes, pregnancy can compound adverse SDOH, increasing both risks and disparities in perinatal outcomes. To effectively manage pregestational diabetes, healthcare professionals must expand their clinical knowledge to understand impact of SDOH, and systematically screen and refer to relevant social support programs. The root causes of SDOH lie in the systems and policies; engaging in advocacy is only way to enact systemic change and complements any individual-level efforts. This review aims to improve adverse perinatal outcomes by providing practical clinical tools to address SDOH in pregestational diabetes in European context.

Keywords

pregestational diabetes

pregnancy

diabetes mellitus type 1

diabetes mellitus type 2

social determinants of health

social disparities

Europe

© 2025 The Authors. Published by Elsevier Ltd.

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