Personal Social Network Analysis in Cerebellar Ataxia: Exploring Correlations with Quality of Life and Functional Outcomes

Ashizawa T, Xia G. Ataxia. Continuum. 2016;22(4 Movement Disorders):1208–26. https://doi.org/10.1212/CON.0000000000000362.

Article  PubMed  PubMed Central  Google Scholar 

Schmahmann JD. The cerebellum and cognition. Neurosci Lett. 2019;688:62–75. https://doi.org/10.1016/j.neulet.2018.07.005.

Article  PubMed  CAS  Google Scholar 

https://www.who.int/standards/classifications/international-classification-of-functioning-disability-and-health. Accessed 1 Dec 2025.

Simmel G. The web of group affiliations. New York: The free press; 1950.

Google Scholar 

Scott, R. Davis, G. Organizations and Organizing. 1st edn. Taylor and Francis. 2015. Available at: https://www.perlego.com/book/2192623/organizations-and-organizing-rational-natural-and-open-systems-perspectives-pdf. Accessed 15 Oct 2022.

de Nooy, W. Social network analysis, graph theoretical approaches to. In: Meyers, R, editor. Encyclopedia of complexity and systems science. Springer, New York, NY; 2009. https://doi.org/10.1007/978-0-387-30440-3_488.

Dhand A, Luke DA, Lang CE, Lee JM. Social networks and neurological illness. Nat Rev Neurol. 2016;12:605–12.

Article  PubMed  PubMed Central  Google Scholar 

Prust M, Halm A, Nedelcu S, Nieves A, Dhand A. Head-to-head comparison of social network assessments in stroke survivors. Neurohospitalist. 2021;11(1):18–24. https://doi.org/10.1177/1941874420945889.

Article  PubMed  Google Scholar 

Christakis NA, Fowler JH. The collective dynamics of smoking in a large social network. N Engl J Med. 2008;358(21):2249–58. https://doi.org/10.1056/NEJMsa0706154.

Article  PubMed  PubMed Central  CAS  Google Scholar 

Berkman LF, Glass T, Brissette I, Seeman TE. From social integration to health: Durkheim in the new millennium. Soc Sci Med. 2000;51(6):843–57. https://doi.org/10.1016/s0277-9536(00)00065-4.

Article  PubMed  CAS  Google Scholar 

Cornwell B, Laumann EO. The health benefits of network growth: new evidence from a national survey of older adults. Soc Sci Med. 2015;125:94–106.

Article  PubMed  Google Scholar 

Glass TA, Matchar DB, Belyea M, Feussner JR. Impact of social support on outcome in first stroke. Stroke. 1993;24(1):64–70. https://doi.org/10.1161/01.str.24.1.64.

Article  PubMed  CAS  Google Scholar 

House JS, Landis KR, Umberson D. Social relationships and health. Science. 1988;241(4865):540–5.

Article  PubMed  CAS  Google Scholar 

Cacioppo JT, Cacioppo S. Social relationships and health: the toxic effects of perceived social isolation. Soc Personal Psychol Compass. 2014;8(2):58–72. https://doi.org/10.1111/spc3.12087.

Article  PubMed  PubMed Central  Google Scholar 

Fratiglioni L, Paillard-Borg S, Winblad B. An active and socially integrated lifestyle in late life might protect against dementia. Lancet Neurol. 2004;3:343–53.

Article  PubMed  Google Scholar 

Bennett DA, Schneider JA, Tang Y, Arnold SE, Wilson RS. The effect of social networks on the relation between Alzheimer’s disease pathology and level of cognitive function in old people: a longitudinal cohort study. Lancet Neurol. 2006;5(5):406–12. https://doi.org/10.1016/S1474-4422(06)70417-3.

Article  PubMed  Google Scholar 

Hsiao YH, Chang CH, Gean PW. Impact of social relationships on Alzheimer’s memory impairment: mechanistic studies. J Biomed Sci. 2018;25(1):3. https://doi.org/10.1186/s12929-018-0404-x.

Article  PubMed  PubMed Central  CAS  Google Scholar 

Manchella MK, Logan PE, Perry BL, Peng S, Risacher SL, Saykin AJ, et al. Associations between social network characteristics and brain structure among older adults. Alzheimers Dement. 2024;20(2):1406–20. https://doi.org/10.1002/alz.13534.

Article  PubMed  CAS  Google Scholar 

Lei Y, Nougaisse J, Malek M, Mishu MM, Bai Y, Denney K, et al. Chronic social isolation-unpredictable stress induces early-onset cognitive deficits and exacerbates Aβ accumulation in the 5xFAD mouse model of Alzheimer’s disease. Mol Psychiatry. 2025. https://doi.org/10.1038/s41380-025-03067-0.

Article  PubMed  PubMed Central  Google Scholar 

Allen K, Blascovich J, Mendes WB. Cardiovascular reactivity and the presence of pets, friends, and spouses: the truth about cats and dogs. Psychosom Med. 2002;64(5):727–39. https://doi.org/10.1097/01.psy.0000024236.11538.41.

Article  PubMed  Google Scholar 

Friedman E, Krause-Parello CA. Companion animals and human health: benefits, challenges, and the road ahead for human-animal interaction. Rev Sci Tech. 2018;37(1):71–82. https://doi.org/10.20506/rst.37.1.2741.

Article  PubMed  CAS  Google Scholar 

McDonough IM, Erwin HB, Sin NL, Allen RS. Pet ownership is associated with greater cognitive and brain health in a cross-sectional sample across the adult lifespan. Front Aging Neurosci. 2022;14:953889. https://doi.org/10.3389/fnagi.2022.953889.

Article  PubMed  PubMed Central  Google Scholar 

Friedmann E, Thomas SA, Son H, Chapa D, McCune S. Pet’s presence and owner’s blood pressures during the daily lives of pet owners with pre- to mild hypertension. Anthrozoos. 2013;26:535–50. https://doi.org/10.2752/175303713X13795775536138.

Article  Google Scholar 

Friedmann E, Gee NR, Simonsick EM, Studenski S, Resnick B, Barr E, et al. Pet ownership patterns and successful aging outcomes in community dwelling older adults. Front Vet Sci. 2020;7:293. https://doi.org/10.3389/fvets.2020.00293.

Article  PubMed  PubMed Central  Google Scholar 

Li Y, Wang W, Zhu L, Yang L, Wu H, Zhang X, et al. Pet ownership, living alone, and cognitive decline among adults 50 years and older. JAMA Netw Open. 2023;6(12):e2349241. https://doi.org/10.1001/jamanetworkopen.2023.49241.

Article  PubMed  PubMed Central  Google Scholar 

Dhand A, Lang CE, Luke DA, Kim A, Li K, McCafferty L, et al. Social network mapping and functional recovery within 6 months of ischemic stroke. Neurorehabil Neural Repair. 2019;33(11):922–32. https://doi.org/10.1177/1545968319872994.

Article  PubMed  PubMed Central  Google Scholar 

Whoqol GROUP. Development of the world health organization WHOQOL-BREF quality of life assessment. Psychol Med. 1998;28(3):551–8. https://doi.org/10.1017/S0033291798006667.

Article  Google Scholar 

Klockgether T, Lüdtke R, Kramer B, Abele M, Bürk K, Schöls L, et al. The natural history of degenerative ataxia: a retrospective study in 466 patients. Brain. 1998;121(Pt 4):589–600. https://doi.org/10.1093/brain/121.4.589.

Article  PubMed  Google Scholar 

Subramony SH, May W, Lynch D, Gomez C, Fischbeck K, Hallett M, et al. Measuring Friedreich ataxia: interrater reliability of a neurologic rating scale. Neurology. 2005;64:1261–2. https://doi.org/10.1212/01.wnl.0000156802.15466.79.

Article  PubMed  CAS  Google Scholar 

Traschütz A, Fleszar Z, Hengel H, Klockgether T, Erdlenbruch F, Falkenburger BH, et al. FARS-ADL across ataxias: construct validity, sensitivity to change, and minimal important change. Mov Disord. 2024;39(6):965–74. https://doi.org/10.1002/mds.29788.

Article  PubMed  CAS  Google Scholar 

Levin SN, Riley CS, Dhand A, White CC, Venkatesh S, Boehm B, et al. Association of social network structure and physical function in patients with multiple sclerosis. Neurology. 2020;95(15):e1565–74. https://doi.org/10.1212/WNL.0000000000010460.

Article  PubMed  PubMed Central  CAS  Google Scholar 

Dhand A, White CC, Johnson C, Xia Z, De Jager PL. A scalable online tool for quantitative social network assessment reveals potentially modifiable social environmental risks. Nat Commun. 2018;9(1):3930. https://doi.org/10.1038/s41467-018-06408-6.

Article  PubMed 

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