Inflammatory Markers as Predictors of Atherosclerotic Plaque Burden and Future Major Adverse Cardiovascular Events: Insights from a Tertiary Care Centre of Southeast Asia

Brown JC, Gerhardt TE, Kwon E. Risk factors for coronary artery disease. [Updated 2023 Jan 23]. In: StatPearls [Internet]. Treasure Island (FL): StatPearls Publishing; 2023 Jan. Available from: https://www.ncbi.nlm.nih.gov/books/NBK554410/.

World Health Organisation [Internet]. Switzerland: World Health Organisation; 1948. Cardiovascular diseases; 2023 [2023 May 11]; [about 1 screen]. Available from: https://www.who.int/health-topics/cardiovascular-diseases#tab=tab_1.

Glovaci D, Fan W, Wong ND. Epidemiology of diabetes mellitus and cardiovascular disease. Curr Cardiol Rep. 2019;21(4):21. https://doi.org/10.1007/s11886-019-1107-y.

Article  PubMed  Google Scholar 

Gupta R, Mohan I, Narula J. Trends in coronary heart disease epidemiology in India. Ann Glob Health. 2016;82(2):307–15. https://doi.org/10.1016/j.aogh.2016.04.002.

Article  PubMed  Google Scholar 

Ardeshna DR, Bob-Manuel T, Nanda A, Sharma A, Skelton WP 4th, Skelton M, et al. Asian-Indians: a review of coronary artery disease in this understudied cohort in the United States. Ann Transl Med. 2018;6(1):12. https://doi.org/10.21037/atm.2017.10.18.

Article  PubMed  PubMed Central  Google Scholar 

Mulrow PJ. The heart is an endocrine gland. Trans Am Clin Climatol Assoc. 1986;97:105–14.

CAS  PubMed  PubMed Central  Google Scholar 

Kobiyama K, Ley K. Atherosclerosis: a chronic inflammatory disease with an autoimmune component. Circ Res. 2018;123(10):1118–11120. https://doi.org/10.1161/CIRCRESAHA.118.313816.

Article  CAS  PubMed  PubMed Central  Google Scholar 

Henein MY, Vancheri S, Longo G, Vancheri F. The role of inflammation in cardiovascular disease. Int J Mol Sci. 2022;23(21):12906. https://doi.org/10.3390/ijms23212906.

Article  PubMed  PubMed Central  Google Scholar 

Willerson JT, Ridker PM. Inflammation as a cardiovascular risk factor. Circulation. 2004;109(21:1):II–2. https://doi.org/10.1161/01.CIR.0000129535.04194.38.

Article  Google Scholar 

Libby P. Inflammation and cardiovascular disease mechanisms. Am J Clin Nutr. 2006;83(2):456S-460S. https://doi.org/10.1093/ajcn/83.2.456S.

Article  CAS  PubMed  Google Scholar 

Fioranelli M, Bottaccioli AG, Bottaccioli F, Bianchi M, Rovesti M, Roccia MG. Stress and inflammation in coronary artery disease: a review psychoneuroendocrineimmunology-based. Front Immunol. 2018;9:2031. https://doi.org/10.3389/fimmu.2018.02031.

Article  CAS  PubMed  PubMed Central  Google Scholar 

Mou-yue W, Huan L. Inflammation in coronary artery diseases. Chin Med J. 2011;124(21):3568–75. https://doi.org/10.3760/cma.j.issn.0366-6999.2011.21.024.

Article  CAS  Google Scholar 

Hochholzer W, Marrow DA, Giugliano RP. Novel markers in cardiovascular disease: update 2010. Am Heart J. 2010;160:583–94. https://doi.org/10.1016/j.ahj.2010.06.010.

Article  CAS  PubMed  Google Scholar 

Bonetti PO. Important classifications and scores in cardiology. Ther Umsch. 2013;70(10):581–8. https://doi.org/10.1024/0040-5930/a000451.

Article  PubMed  Google Scholar 

Ndrepepa G. High-density lipoprotein: a double-edged sword in cardiovascular physiology and pathophysiology. J Lab Precis Med. 2021;6(32):28. https://doi.org/10.21037/jlpm-21-32.

Article  Google Scholar 

Hunjadi M, Lamina C, Kahler P, Bernscherer T, Viikari J, Lehtimäki T, et al. HDL cholesterol efflux capacity is inversely associated with subclinical cardiovascular risk markers in young adults: the cardiovascular risk in Young Finns study. Sci Rep. 2020;10(1):19223. https://doi.org/10.1038/s41598-020-76146-7.

Article  CAS  PubMed  PubMed Central  Google Scholar 

Magnoni M, Andreini D, Pirillo A, Uboldi P, Latini R, Catapano AL, et al. Predictive value of HDL function in patients with coronary artery disease: relationship with coronary plaque characteristics and clinical events. Ann Med. 2022;54(1):1036–46. https://doi.org/10.1038/s41598-020-76146-7.

Article  CAS  PubMed  PubMed Central  Google Scholar 

Tousoulis D, Charakida M, Stefanadis C. Endothelial function and inflammation in coronary artery disease. Heart. 2006;92:441–4. https://doi.org/10.1136/hrt.2005.066936.

Article  CAS  PubMed  Google Scholar 

Sharif Nia H, Sivarajan-Froelicher E, Haghdoost AA, Moosazadeh M, Huak-Chan Y, Farsavian AA, et al. The estimate of average age at the onset of acute myocardial infarction in Iran: a systematic review and meta-analysis study. ARYA Atheroscler. 2018;14(5):225–32. https://doi.org/10.22122/arya.v14i5.1739.

Article  PubMed  PubMed Central  Google Scholar 

Iragavarapu T, Radhakrishna T, Babu KJ, Sanghamitra R. Acute coronary syndrome in young-a tertiary care centre experience with reference to coronary angiogram. J Pract Cardiovasc Sci. 2019;5(1):18–25. https://doi.org/10.4103/jpcs.jpcs_74_18.

Article  Google Scholar 

Virani SS, Alonso A, Benjamin EJ, Bittencourt MS, Callaway CW, Carson AP, et al. Heart disease and stroke statistics—2020 update: a report from the American Heart Association. Circulation. 2020;141(9):e139-596. https://doi.org/10.1161/CIR.0000000000000757.

Article  PubMed  Google Scholar 

Joshi P, Islam S, Pais P, Reddy S, Dorairaj P, Kazmi K, et al. Risk factors for early myocardial infarction in South Asians compared with individuals in other countries. JAMA. 2007;297(3):286–94. https://doi.org/10.1001/jama.297.3.286.

Article  CAS  PubMed  Google Scholar 

Neel JV. Diabetes mellitus: a “thrifty” genotype rendered detrimental by “progress”? Am J Hum Genet. 1962;14(4):353–436.

CAS  PubMed  PubMed Central  Google Scholar 

Elbarouni B, Goodman SG, Yan RT, Welsh RC, Kornder JM, DeYoung JP, et al. Validation of the Global Registry of Acute Coronary Event (GRACE) risk score for in-hospital mortality in patients with acute coronary syndrome in Canada. Am Heart J. 2009;158(3):392–9. https://doi.org/10.1016/j.ahj.2009.06.010.

Article  PubMed  Google Scholar 

Aguado-Romeo MJ, Márquez-Calderón S, Buzón-Barrera ML, Medical Practice Variations Andalusian Group. Hospital mortality in acute coronary syndrome: differences related to gender and use of percutaneous coronary procedures. BMC Health Serv Res. 2007;7:1–7. https://doi.org/10.1186/1472-6963-7-110.

Article  Google Scholar 

Sharma YP, Vemuri KS, Bootla D, Kanabar K, Pruthvi CR, Kaur N, et al. Epidemiological profile, management and outcomes of patients with acute coronary syndrome: single centre experience from a tertiary care hospital in North India. Indian Heart J. 2021;73(2):174–9. https://doi.org/10.1016/j.ihj.2020.11.149.

Article  PubMed  PubMed Central  Google Scholar 

Pramudyo M, Yahya AF, Martanto E, Tiksnadi BB, Karwiky G, Rafidhinar R, et al. Predictors of in-hospital mortality in patients with acute coronary syndrome in hasan sadikin hospital, bandung, indonesia: a retrospective cohort study. Acta Med Indones. 2022;54(3):379–88.

PubMed  Google Scholar 

Marinho L, Aday AW, Cook NR, Morrison AR, Narula N, Narula J, et al. Plasma interleukin-6 levels and cardiovascular events in the cirt trial: consistent associations for incident coronary, cerebrovascular, and peripheral artery disease. Arteriosclerosis Thrombosis Vasc Biol. 2022;42(1):A140. https://doi.org/10.1161/atvb.42.suppl_1.140.

Article  Google Scholar 

Fanola CL, Morrow DA, Cannon CP, Jarolim P, Lukas MA, Bode C, et al. Interleukin‐6 and the risk of adverse outcomes in patients after an acute coronary syndrome: observations from the SOLID‐TIMI 52 (stabilization of plaque using darapladib—thrombolysis in myocardial infarction 52) trial. J Am Heart Assoc. 2017;6(10):e005637. https://doi.org/10.1161/JAHA.117.005637.

Article  PubMed  PubMed Central  Google Scholar 

McCabe JJ, Walsh C, Gorey S, Harris K, Hervella P, Iglesias-Rey R, et al. C-reactive protein, interleukin-6, and vascular recurrence after stroke: an individual participant data meta-analysis. Stroke. 2023;54(5):1289–99. https://doi.org/10.1161/STROKEAHA.122.040529.

Article  CAS  PubMed  Google Scholar 

Tabaei S, Motallebnezhad M, Tabaee SS. Systematic review and meta-analysis of association of polymorphisms in inflammatory cytokine genes with coronary artery disease. Inflamm Res. 2020;69:1001–13. https://doi.org/10.1007/s00011-020-01385-3.

Article  CAS  PubMed 

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