The Effects of Cigarette Smoking and Chronic Alcohol Consumption on Seminal Quality in Young Adults: A Cross-Sectional Study

Gaur DS, Talekar MS, Pathak VP. Alcohol intake and cigarette smoking: impact of two major lifestyle factors on male fertility. Indian J Pathol Microbiol. 2010;53(1):35–40.

Article  PubMed  Google Scholar 

Parameswari R, Sridharan TB. Cigarette smoking and its toxicological overview on human male fertility: a prospective review. Toxin Rev. 2021;40(2):145–61.

Article  CAS  Google Scholar 

Harlev A, Agarwal A, Gunes SO, Shetty A, du Plessis SS. Smoking and male infertility: an evidence-based review. World J Mens Health. 2015;33(3):143–60.

Article  PubMed  PubMed Central  Google Scholar 

Mahdavinezhad F, Gharaei R, Farmani AR, Hashemi F, Kouhestani M, Amidi F. The potential relationship between different human female reproductive disorders and sperm quality in the female genital tract. Reprod Sci. 2022;29(3):695–710.

Article  PubMed  Google Scholar 

Rodriguez-Martinez H, Martinez EA, Calvete JJ, Pena Vega FJ, Roca J. Seminal plasma: relevant for fertility? Int J Mol Sci. 2021;22(9):4368.

Article  CAS  PubMed  PubMed Central  Google Scholar 

Abilash D, Parameswari R, Madhan Kumar P, Sridharan TB. A study on the role of oxidative stress on the sperm quality of individuals occupationally exposed to air pollution. Indian J Clin Biochem. 2025;40:1–11.

Google Scholar 

Sridharan TB, Abilash D. Heavy metal exposure and its consequences on sperm quality: a cross-sectional perspective study. Indian J Clin Biochem. 2025. https://doi.org/10.1007/s12291-025-01350-z.

Article  Google Scholar 

Jiang Y, Zhang T, Kusumanchi P, Han S, Yang Z, Liangpunsakul S. Alcohol metabolizing enzymes, microsomal ethanol oxidizing system, cytochrome P450 2E1, catalase, and aldehyde dehydrogenase in alcohol-associated liver disease. Biomedicines. 2020;8(3):50.

Article  CAS  PubMed  PubMed Central  Google Scholar 

Wu J, Meng QH. Current understanding of the metabolism of micronutrients in chronic alcoholic liver disease. World J Gastroenterol. 2020;26(31):4567–79.

Article  CAS  PubMed  PubMed Central  Google Scholar 

Van Thiel DH, Lester R. Alcoholism: its effect on hypothalamic–pituitary–gonadal function. Gastroenterology. 1976;71(2):318–27.

Article  CAS  PubMed  Google Scholar 

Nussdorfer P, Cilenšek I, Zorn B, Petrovič D. Adapted methods for scanning electron microscopy in assessment of human sperm morphology. Bosn J Basic Med Sci. 2018;18(1):43–9.

CAS  PubMed  PubMed Central  Google Scholar 

Abilash D, Sridharan TB. Impact of air pollution and heavy metal exposure on sperm quality: a clinical prospective research study. Toxicol Rep. 2024;13:101708.

Article  Google Scholar 

Lewis-Jones DI, Aird IA, Biljan MM, Kingsland CR. Effects of sperm activity on zinc and fructose concentrations in seminal plasma. Hum Reprod. 1996;11(11):2465–7.

Article  CAS  PubMed  Google Scholar 

Agarwal A, Gupta S, Sharma R. Eosin-nigrosin staining procedure. In: Agarwal A, Gupta S, Sharma R, editors. Andrological evaluation of male infertility: a laboratory guide. Cham: Springer; 2016. p. 73–7.

Chapter  Google Scholar 

Esfandiari N, Sharma RK, Saleh RA, Thomas Jr AJ, Agarwal A. Utility of the nitroblue tetrazolium reduction test for assessment of reactive oxygen species production by seminal leukocytes and spermatozoa. J Androl. 2003;24(6):862–70.

Javvaji PK, Dhali A, Francis JR, Kolte AP, Mech A, Roy SC, et al. An efficient nitroblue tetrazolium staining and bright-field microscopy-based method for detecting and quantifying intracellular reactive oxygen species in oocytes, cumulus cells and embryos. Front Cell Dev Biol. 2020;8:764.

Article  PubMed  PubMed Central  Google Scholar 

Agbaje IM, McVicar CM, Schock BC, McClure N, Atkinson AB, Rogers D, et al. Increased concentrations of 8-oxo-2′-deoxyguanosine in the germline of men with type 1 diabetes. Reprod Biomed Online. 2008;16(3):401–9.

Article  CAS  PubMed  Google Scholar 

Suleiman SA, Ali ME, Zaki ZM, El-Malik EM, Nasr MA. Lipid peroxidation and human sperm motility: protective role of vitamin E. J Androl. 1996;17(5):530–7.

Article  CAS  PubMed  Google Scholar 

Aitken RJ, Buckingham DW, Carreras A, Irvine DS. Superoxide dismutase in human sperm suspensions: relationship with cellular composition, oxidative stress, and sperm function. Free Radic Biol Med. 1996;21(4):495–504.

Article  CAS  PubMed  Google Scholar 

Jeulin C, Soufir JC, Weber P, Laval-Martin D, Calvayrac R. Catalase activity in human spermatozoa and seminal plasma. Gamete Res. 1989;24(2):185–96.

Article  CAS  PubMed  Google Scholar 

Doraiah A, Balasundharam ST. The ameliorative and cryoprotective activity of Senna auriculata L. flower extract on the semen of men exposed to air pollution: a prospective study. Int J Infertil Fetal Med. 2024. https://doi.org/10.5005/jp-journals-10016-1388.

Article  Google Scholar 

Ranganathan P, Rao KA, Sudan JJ, Balasundaram S. Cadmium effects on sperm morphology and semenogelin with relation to increased reactive oxygen species in infertile smokers: an in vitro and in silico approach. Reprod Biol. 2018;18(2):189–97.

Article  PubMed  Google Scholar 

Henson MC, Chedrese PJ. Endocrine disruption by cadmium, a common environmental toxicant with paradoxical effects on reproduction. Exp Biol Med. 2004;229(5):383–92.

Article  CAS  Google Scholar 

Dorostghoal M, Kazeminejad SR, Shahbazian N, Pourmehdi M, Jabbari A. Oxidative stress status and sperm DNA fragmentation in fertile and infertile men. Andrologia. 2017;49(10):e12762.

Article  Google Scholar 

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