Barker RA, Björklund A, Gash DM, Whone A, Van Laar A, Kordower JH, Bankiewicz K, Kieburtz K, Saarma M, Booms S, Huttunen HJ, Kells AP, Fiandaca MS, Stoessl AJ, Eidelberg D, Federoff H, Voutilainen MH, Dexter DT, Eberling J, Brundin P, Isaacs L, Mursaleen L, Bresolin E, Carroll C, Coles A, Fiske B, Matthews H, Lungu C, Wyse RK, Stott S, Lang AE (2020) GDNF and Parkinson’s disease: where next? A summary from a recent workshop. J Parkinsons Dis 10(3):875–891

Article  CAS  PubMed  PubMed Central  Google Scholar 

Ben-Shlomo R, Kyriacou CP (2010) Light pulses administered during the circadian dark phase alter expression of cell cycle associated transcripts in mouse brain. Cancer Genet Cytogenet 197(1):65–70

Article  CAS  PubMed  Google Scholar 

Bhattarai C, Poudel PP, Ghosh A, Kalthur SG (2022) The RET gene encodes RET protein, which triggers intracellular signaling pathways for enteric neurogenesis, and RET mutation results in Hirschsprung’s disease. AIMS Neurosci 9(1):128–149

Article  PubMed  PubMed Central  Google Scholar 

Blom K, Koek HL, Zwartbol MHT, Ghaznawi R, Kuijf HJ, Witkamp TD, Hendrikse J, Biessels GJ, UCC-SMART Study Group (2020) Vascular risk factors of hippocampal subfield volumes in persons without dementia: the medea 7T study. J Alzheimers Dis 77(3):1223–1239

Article  PubMed  PubMed Central  Google Scholar 

Cao D, Bai Y, Li L (2018) Common carotid arteries occlusion surgery in adult rats as a model of chronic cerebral hypoperfusion. Bio Protoc 8(2):e2704

Article  PubMed  PubMed Central  Google Scholar 

Chen L, Xie X, Wang T, Xu L, Zhai Z, Wu H, Deng L, Lu Q, Chen Z, Yang X, Lu H, Chen YG, Luo S (2023) ARL13B promotes angiogenesis and glioma growth by activating VEGFA-VEGFR2 signaling. Neuro Oncol 25(5):871–885

Article  CAS  PubMed  PubMed Central  Google Scholar 

Choi DH, Lee KH, Lee J (2016) Effect of exercise-induced neurogenesis on cognitive function deficit in a rat model of vascular dementia. Mol Med Rep 13(4):2981–2990

Article  CAS  PubMed  PubMed Central  Google Scholar 

Cox MA, Bassi C, Saunders ME, Nechanitzky R, Morgado-Palacin I, Zheng C, Mak TW (2020) Beyond neurotransmission: acetylcholine in immunity and inflammation. J Intern Med 287(2):120–133

Article  CAS  PubMed  Google Scholar 

Cui Y, Wang JQ, Shi XH, Wang YY, Liu HY, Li Z, Dong Y, Mang J, Xu ZX (2019) Nodal mitigates cerebral ischemia-reperfusion injury via inhibiting oxidative stress and inflammation. Eur Rev Med Pharmacol Sci 23(13):5923–5933

CAS  PubMed  Google Scholar 

Dietz RM, Dingman AL, Herson PS (2022) Cerebral ischemia in the developing brain. J Cereb Blood Flow Metab 42(10):1777–1796

Article  CAS  PubMed  PubMed Central  Google Scholar 

Dobryakova YV, Bolshakov AP, Korotkova T, Rozov AV (2025) Acetylcholine in the hippocampus: problems and achievements. Front Neural Circuits 19:1491820

Article  CAS  PubMed  PubMed Central  Google Scholar 

Du SQ, Wang XR, Xiao LY, Tu JF, Zhu W, He T, Liu CZ (2017) Molecular mechanisms of vascular dementia: what can be learned from animal models of chronic cerebral hypoperfusion? Mol Neurobiol 54(5):3670–3682

Article  CAS  PubMed  Google Scholar 

Eguchi R, Kawabe JI, Wakabayashi I (2022) VEGF-independent angiogenic factors: beyond VEGF/VEGFR2 signaling. J Vasc Res 59(2):78–89

Article  CAS  PubMed  Google Scholar 

Fei J, Chen S, Song X, Liang Y, Duan K, Peng X, Li L (2024) Exogenous GDNF promotes peripheral facial nerve regeneration in rats through the PI3K/AKT/mTOR signaling pathway. FASEB J 38(1):e23340

Article  CAS  PubMed  Google Scholar 

Gao Y, Ma K, Zhu Z, Zhang Y, Zhou Q, Wang J, Guo X, Luo L, Wang H, Peng K, Liu M (2023) Modified erchen decoction ameliorates cognitive dysfunction in vascular dementia rats via inhibiting JAK2/STAT3 and JNK/BAX signaling pathways. Phytomedicine 114:154797

Article  CAS  PubMed  Google Scholar 

Hosoki S, Hansra GK, Jayasena T, Poljak A, Mather KA, Catts VS, Rust R, Sagare A, Kovacic JC, Brodtmann A, Wallin A, Zlokovic BV, Ihara M, Sachdev PS (2023) Molecular biomarkers for vascular cognitive impairment and dementia. Nat Rev Neurol 19(12):737–753

Article  CAS  PubMed  Google Scholar 

Jelic MD, Mandic AD, Maricic SM, Srdjenovic BU (2021) Oxidative stress and its role in cancer. J Cancer Res Ther 17(1):22–28

Article  CAS  PubMed  Google Scholar 

Kakati RT, Kim H, Whitman A, Spanheimer PM (2023) High expression of the RET receptor tyrosine kinase and its ligand GDNF identifies a high-risk subset of estrogen receptor positive breast cancer. Breast Cancer Res Treat 199(3):589–601

Article  CAS  PubMed  PubMed Central  Google Scholar 

Kakoty V, Sarathlal KC, Kaur P, Wadhwa P, Vishwas S, Khan FR, Alhazmi AYM, Almasoudi HH, Gupta G, Chellappan DK, Paudel KR, Kumar D, Dua K, Singh SK (2024) Unraveling the role of glial cell line-derived neurotrophic factor in the treatment of Parkinson’s disease. Neurol Sci 45(4):1409–1418

Article  PubMed  Google Scholar 

Kang K, Wang DP, Lv QL, Chen F (2023) VEGF-A ameliorates ischemia hippocampal neural injury via regulating autophagy and Akt/CREB signaling in a rat model of chronic cerebral hypoperfusion. J Stroke Cerebrovasc Dis 32(11):107367

Article  PubMed  Google Scholar 

Kong D, Luo J, Shi S, Huang Z (2021) Efficacy of tanshinone IIA and mesenchymal stem cell treatment of learning and memory impairment in a rat model of vascular dementia. J Tradit Chin Med 41(1):133–139

PubMed  Google Scholar 

de Leo G, Gulino R, Coradazzi M, Leanza G (2022) Acetylcholine and noradrenaline differentially regulate hippocampus-dependent spatial learning and memory. Brain Commun 5(1):fcac338

Article  PubMed  PubMed Central  Google Scholar 

Liu H, Weng J (2022) A comprehensive bioinformatic analysis of cyclin-dependent kinase 2 (CDK2) in glioma. Gene 822:146325

Article  CAS  PubMed  Google Scholar 

Liu H, Dilger JP, Lin J (2020) The role of transient receptor potential melastatin 7 (TRPM7) in cell viability: a potential target to suppress breast cancer cell cycle. Cancers (Basel) 12(1):131

Article  CAS  PubMed  PubMed Central  Google Scholar 

Liu H, Zang C, Shang J, Zhang Z, Wang L, Yang H, Sheng C, Yuan F, Ju C, Li F, Yu Y, Yao X, Bao X, Zhang D (2022) Gardenia jasminoides J. Ellis extract GJ-4 attenuates hyperlipidemic vascular dementia in rats via regulating PPAR-γ-mediated microglial polarization. Food Nutr Res 66:1–15

Article  Google Scholar 

Mallone F, Sacchetti M, Bruscolini A, Scuderi L, Marenco M, Lambiase A (2020) Neurotrophic factors in glaucoma and innovative delivery systems. Appl Sci 10(24):9015

Article  CAS  Google Scholar 

Ming M, Hu W, Xie G, Chen J, Huang Y (2023) Dendrobium nobile polysaccharides attenuates ferroptosis and improves cognitive function in vascular dementia rats. American Journal of Alzheimer’s Disease & Other Dementias® 38:15333175231185236

Article  Google Scholar 

Nan S, Wang P, Zhang Y, Fan J (2021) Epigallocatechin-3-gallate provides protection against Alzheimer’s disease-induced learning and memory impairments in rats. Drug Des Devel Ther 15:2013–2024

Article  PubMed  PubMed Central  Google Scholar 

Niu X, Li M, Gao Y, Xu G, Dong X, Chu B, Lv P (2021) DL-3-n-butylphthalide suppressed autophagy and promoted angiogenesis in rats with vascular dementia by activating the Shh/Ptch1 signaling pathway. Neurosci Lett 765:136266

Article  CAS  PubMed  Google Scholar 

Othman MZ, Hassan Z, Che Has AT (2022) Morris water maze: a versatile and pertinent tool for assessing spatial learning and memory. Exp Anim 71(3):264–280

Article  CAS  PubMed  PubMed Central