Objective Structured Clinical Examinations (OSCEs) are widely used to assess medical students’ clinical skills, including non-technical abilities such as communication and empathy. However, the potential influence of individual psychological traits—such as personality dimensions, empathy, and stress-related mindset—on OSCE performance remains understudied. This study investigated associations between personality traits, empathy levels, stress mindsets, and performance in OSCEs among medical students.

An online questionnaire (including the Big Five Personality Traits Inventory 2, the Jefferson Scale of Physician Empathy (Medical Student version), the Growth Mindset Scale, the Stress Mindset Measure) was provided to all fifth-year medical students enrolled at the Université Paris Cité for six weeks before undertaking graduation summative OSCEs. Their scores were correlated with OSCE performance using Spearman’s correlation and linear regression analyses.

A total of 99 questionnaires were included and analysed. None of the psychometric tests we assessed showed a significant correlation with OSCE scores. The strongest predictors of success in OSCEs were higher scores in written examinations, previous OSCE performance, and being female. In non-interactive OSCE stations, conscientiousness was the only significant predictor, with a positive association (p=0.001). Neuroticism was positively associated with performance improvement between OSCE sessions (p=0.042).

Personality traits, self-reported empathy, and stress-related mindsets do not predict success in OSCEs as isolated traits. Further research is needed to determine whether it holds true for all kinds of OSCEs. Multidimensional psychometric assessment may be relevant when investigating performance outcomes in OSCEs.

The authors have declared no competing interest.

None.

I confirm all relevant ethical guidelines have been followed, and any necessary IRB and/or ethics committee approvals have been obtained.

Yes

The details of the IRB/oversight body that provided approval or exemption for the research described are given below:

Ethical approval: The Institutional Review Board (IRB) of the Universite Paris Cite authorised our study (number 00012024-21). Informed consent was obtained from all participants.

I confirm that all necessary patient/participant consent has been obtained and the appropriate institutional forms have been archived, and that any patient/participant/sample identifiers included were not known to anyone (e.g., hospital staff, patients or participants themselves) outside the research group so cannot be used to identify individuals.

Yes

I understand that all clinical trials and any other prospective interventional studies must be registered with an ICMJE-approved registry, such as ClinicalTrials.gov. I confirm that any such study reported in the manuscript has been registered and the trial registration ID is provided (note: if posting a prospective study registered retrospectively, please provide a statement in the trial ID field explaining why the study was not registered in advance).

Yes

I have followed all appropriate research reporting guidelines, such as any relevant EQUATOR Network research reporting checklist(s) and other pertinent material, if applicable.

Yes

The datasets used during this study are available from the corresponding author on reasonable request.