Rastogi S, Mittal V, Singh A (2020a) In vitro evaluation of probiotic potential and safety assessment of Lactobacillus mucosae strains isolated from donkey’s lactation. Probiotics Antimicrob Proteins 12:1045–1056. https://doi.org/10.1007/s12602-019-09610-0

Article  CAS  PubMed  Google Scholar 

Rastogi S, Mittal V, Singh A (2020b) In vitro assessment of antioxidant and antimicrobial potential of Lactobacillus gasseri strains isolated from human milk and infant faeces. J Pure Appl Microbiol 14(2):1305–1315. https://doi.org/10.22207/JPAM.14.2.26

Article  CAS  Google Scholar 

Dwivedi M, Powali S, Rastogi S, Singh A, Gupta D (2021) Microbial community in human gut: a therapeutic prospect and implication in health and diseases. Lett Appl Microbiol 73:553–568. https://doi.org/10.1111/lam.13549

Article  CAS  PubMed  Google Scholar 

Rastogi S, Mittal V, Singh A (2021) Selection of potential probiotic bacteria from exclusively breastfed infant faeces with antagonistic activity against multidrug-resistant ESKAPE pathogens. Probiotics Antimicrob Proteins 13:739–750. https://doi.org/10.1007/s12602-020-09724-w

Article  CAS  PubMed  Google Scholar 

Rastogi S, Singh A (2022) Gut microbiome and human health: exploring how the probiotic genus Lactobacillus modulates immune responses. Front Pharmacol 14:1042189. https://doi.org/10.3389/fphar.2022.1042189

Article  CAS  Google Scholar 

Rastogi S, Singh A, Nandi A, Gupta A, Agarwal J, Kostova I (2022) Can the therapeutic spectrum of probiotics be extended: exploring potential of gut microbiome. Recent Adv Antiinfect Drug Discov 8(2):120–147. https://doi.org/10.2174/2772434418666221124124317

Article  CAS  Google Scholar 

Siciliano RA, Reale A, Mazzeo MF, Morandi S, Silvetti T, Brasca M (2021) Paraprobiotics: a new perspective for functional foods and nutraceuticals. Nutrients 13(4):1225. https://doi.org/10.3390/nu13041225

Article  CAS  PubMed  PubMed Central  Google Scholar 

Nataraj BH, Ali SA, Behare PV, Yadav H (2020) Postbiotics-parabiotics: the new horizons in microbial biotherapy and functional foods. Microb Cell Fact 19(1):168. https://doi.org/10.1186/s12934-020-01426-w

Article  CAS  PubMed  PubMed Central  Google Scholar 

Kazemi A, Soltani S, Nasri F, Clark CCT, Kolahdouz-Mohammadi R (2021) The effect of probiotics, parabiotics, synbiotics, fermented foods and other microbial forms on immunoglobulin production: a systematic review and meta-analysis of clinical trials. Int J Food Sci Nutr 72(5):632–649. https://doi.org/10.1080/09637486.2020.1857710

Article  CAS  PubMed  Google Scholar 

Teame T, Wang A, Xie M et al (2020) Paraprobiotics and postbiotics of probiotic Lactobacilli, their positive effects on the host and action mechanisms: a review. Front Nutr 7:570344. https://doi.org/10.3389/fnut.2020.570344

Article  CAS  PubMed  PubMed Central  Google Scholar 

Altieri C, Filippone A, Bevilacqua A, Corbo MR, Sinigaglia M (2024) Lactobacilli and Bifidobacteria: a parapostbiotic approach to study and explain their mutual bioactive influence. Foods 13(18):2966. https://doi.org/10.3390/foods13182966

Article  CAS  PubMed  PubMed Central  Google Scholar 

Ashique S et al (2025) Para-probiotics as Novel Anti-Inflammatory Agents: Insight into Health Benefits and Therapeutic Applications. Curr Pharm Des. 2025. https://doi.org/10.2174/0113816128411949250909113034

Klein G, Schanstra JP, Hoffmann J, Mischak H, Siwy J, Zimmermann K (2013) Proteomics as a quality control tool of pharmaceutical probiotic bacterial lysate products. PLoS One 8(6):e66682. https://doi.org/10.1371/journal.pone.0066682

Article  CAS  PubMed  PubMed Central  Google Scholar 

Holzapfel WH, Schillinger U (2002) Introduction to pre- and probiotics. Food Res Int 35(2–3):109–116. https://doi.org/10.1016/S0963-9969(01)00171-5

Article  Google Scholar 

Isolauri E, Salminen S, Ouwehand AC (2004) Probiotics. Best Pract Res Clin Gastroenterol 18(2):299–313. https://doi.org/10.1016/j.bpg.2003.10.006

Article  PubMed  Google Scholar 

Cebra JJ (1999) Influences of microbiota on intestinal immune system development. Am J Clin Nutr 69(5):1046S–1051S. https://doi.org/10.1093/ajcn/69.5.1046s

Article  CAS  PubMed  Google Scholar 

Hussain A, Ali SA (2025) The Emergence and Prevalence of Antibiotic Resistance in Genus Enterococcus and Their Implications on Probiotics. Antimicrobial Resistance – New Insight. IntechOpen; 2025. https://doi.org/10.5772/intechopen.1009648

Marteau P, Shanahan F (2003) Basic aspects and pharmacology of probiotics: an overview of pharmacokinetics, mechanisms of action and side-effects. Best Pract Res Clin Gastroenterol 17(5):725–740. https://doi.org/10.1016/S1521-6918(03)00055-6

Article  CAS  PubMed  Google Scholar 

Stewart-Tull DES (1980) The immunological activities of bacterial peptidoglycans. Annu Rev Microbiol 34:311–340. https://doi.org/10.1146/annurev.mi.34.100180.001523

Article  CAS  PubMed  Google Scholar 

Akter S, Park JH, Jung HK (2020) Potential health-promoting benefits of paraprobiotics, inactivated probiotic cells. J Microbiol Biotechnol 30(4):477–481. https://doi.org/10.4014/jmb.1911.11019

Article  CAS  PubMed  PubMed Central  Google Scholar 

Sharma N, Kang DK, Paik HD, Park YS (2022) Beyond probiotics: a narrative review on an era of revolution. Food Sci Biotechnol 32(4):413–421. https://doi.org/10.1007/s10068-022-01212-x

Article  PubMed  PubMed Central  Google Scholar 

Costa RL, Moreira J, Lorenzo A, Lamas CC (2018) Infectious complications following probiotic ingestion: a potentially underestimated problem? A systematic review of reports and case series. BMC Complement Altern Med 18(1):329. https://doi.org/10.1186/s12906-018-2394-3

Article  PubMed  PubMed Central  Google Scholar 

Imre A, Rácz HV, Antunovics Z et al (2019) A new, rapid multiplex PCR method identifies frequent probiotic origin among clinical Saccharomyces isolates. Microbiol Res 227:126298. https://doi.org/10.1016/j.micres.2019.126298

Article  CAS  PubMed  Google Scholar 

Cuevas-González PF, Liceaga AM, Aguilar-Toalá JE (2020) Postbiotics and paraprobiotics: from concepts to applications. Food research international (Ottawa, Ont.) 136:109502. https://doi.org/10.1016/j.foodres.2020.109502

Article  CAS  PubMed  Google Scholar 

Wilmes P, Bond PL (2006) Metaproteomics: studying functional gene expression in microbial ecosystems. Trends Microbiol. https://doi.org/10.1016/j.tim.2005.12.006

Article  PubMed  Google Scholar 

Salminen S, Collado MC, Endo A, Hill C, Lebeer S, Quigley EMM et al (2021) The International Scientific Association of Probiotics and Prebiotics (ISAPP) consensus statement on the definition and scope of postbiotics. Nat Rev Gastroenterol Hepatol 18(9):649–667. https://doi.org/10.1038/s41575-021-00440-6

Article  PubMed  PubMed Central  Google Scholar 

Mudaliar SB, Poojary SS, Bharath Prasad AS, Mazumder N (2024) Probiotics and paraprobiotics: effects on Microbiota-Gut-Brain Axis and their consequent potential in Neuropsychiatric Therapy. Probiotics Antimicrob Proteins 16(4):1440–1464. https://doi.org/10.1007/s12602-024-10214-6

Article  CAS  PubMed  PubMed Central  Google Scholar 

Esam RM, Hafez RS, Khafaga NIM, Ahmed LI, Soliman TN, Fahim KM (2025) Novel utilization of micro-encapsulated Lactobacillus acidophilus and bacterial /yeast combination enhanced the AFM1 reduction in spiked yoghurt. Int J Food Microbiol 436:111205. https://doi.org/10.1016/j.ijfoodmicro.2025.111205

Article  CAS  PubMed  Google Scholar 

Liu J, Cook B, Roux S (2020) The challenges in commercialisation of probiotic API manufacturing. Microbiol Aust 41:82–85. https://doi.org/10.1071/MA20021

Article  Google Scholar 

Divsalar E, İncili GK, Shi C, Semsari E, Hosseini SH, Ebrahimi Tirtashi F