Goyal R, Singhal M, Jialal I. Type 2 Diabetes. StatPearls. Treasure Island (FL): StatPearls Publishing; 2023. Available from: https://www.ncbi.nlm.nih.gov/books/NBK513253/

Burgess JL, Wyant WA, Abdo Abujamra B, Kirsner RS, Jozic I. Diabetic wound-healing science. Medicina (Kaunas). 2021. https://doi.org/10.3390/medicina57101072.

Article  PubMed  PubMed Central  Google Scholar 

Huang Y, Kyriakides TR. The role of extracellular matrix in the pathophysiology of diabetic wounds. Matrix Biol Plus. 2020;6–7:100037. https://doi.org/10.1016/j.mbplus.2020.100037.

Article  CAS  PubMed  PubMed Central  Google Scholar 

Kaiser P, Wächter J, Windbergs M. Therapy of infected wounds: overcoming clinical challenges by advanced drug delivery systems. Drug Deliv Transl Res. 2021;11:1545–67. https://doi.org/10.1007/s13346-021-00932-7.

Article  CAS  PubMed  PubMed Central  Google Scholar 

Akkus G, Sert M. Diabetic foot ulcers: A devastating complication of diabetes mellitus continues non-stop in spite of new medical treatment modalities. World J Diabetes., Akkus G, Sert M. Diabetic foot ulcers: A devastating complication of diabetes mellitus continues non-stop in spite of new medical treatment modalities. World J Diabetes 2022; 13(12): 1106–1121. doi: 10.4239/wjd.v13.i12.1106.

Jodheea-Jutton A, Hindocha S, Bhaw-Luximon A. Health economics of diabetic foot ulcer and recent trends to accelerate treatment. Foot (Edinb). 2022;52:101909.

Article  PubMed  Google Scholar 

Baltzis D, Eleftheriadou I, Veves A. Pathogenesis and treatment of impaired wound healing in diabetes mellitus: new insights. Adv Ther. 2014;31:817–36.

Article  CAS  PubMed  Google Scholar 

Boulton AJM, Armstrong DG, Löndahl M, Frykberg RG, Game FL, Edmonds ME. New Evidence-Based Therapies for Complex Diabetic Foot Wounds. Arlington (VA): American Diabetes Association; 2022.

Book  Google Scholar 

Al-Raeei M. Harnessing nanoscale innovations for enhanced healing of diabetic foot ulcers. Endocr Metab Sci. 2025;17:100210.

Article  CAS  Google Scholar 

Sharma R, Borah SJ, Bhawna, Kumar S, Gupta A, Kumari V, et al. Emerging trends in nano-based antidiabetic therapeutics: a path to effective diabetes management. Mater Adv. 2023;4:3091–113.

Article  CAS  Google Scholar 

Spampinato SF, Caruso GI, De Pasquale R, Sortino MA, Merlo S. The treatment of impaired wound healing in diabetes: looking among old drugs. Pharmaceuticals Basel. 2020. https://doi.org/10.3390/ph13040060.

Article  PubMed  PubMed Central  Google Scholar 

Alghamdi MA, Fallica AN, Virzì N, Kesharwani P, Pittalà V, Greish K. The promise of nanotechnology in personalized medicine. J Pers Med. 2022. https://doi.org/10.3390/jpm12050673.

Article  PubMed  PubMed Central  Google Scholar 

Karas RA, Alexeree S, Elsayed H, Attia YA. Assessment of wound healing activity in diabetic mice treated with a novel therapeutic combination of selenium nanoparticles and platelets rich plasma. Sci Rep. 2024;14:5346.

Article  CAS  PubMed  PubMed Central  Google Scholar 

Ahmed R, Augustine R, Chaudhry M, Akhtar UA, Zahid AA, Tariq M, et al. Nitric oxide-releasing biomaterials for promoting wound healing in impaired diabetic wounds: State of the art and recent trends. Biomed Pharmacother. 2022;149:112707.

Article  CAS  PubMed  Google Scholar 

Olteanu G, Neacșu SM, Joița FA, Musuc AM, Lupu EC, Ioniță-Mîndrican C-B, et al. Advancements in regenerative hydrogels in skin wound treatment: a comprehensive review. Int J Mol Sci. 2024. https://doi.org/10.3390/ijms25073849.

Article  PubMed  PubMed Central  Google Scholar 

Anuradha CT, Krishna Sharma R. Nanobiotechnology driven wound care solutions: A critical review of bio-synthesized nanoparticles’ applications. Results Surf Interfaces. 2025;18:100369.

Article  Google Scholar 

Patra JK, Das G, Fraceto LF, Campos EVR, Rodriguez-Torres MDP, Acosta-Torres LS, et al. Nano based drug delivery systems: recent developments and future prospects. J Nanobiotechnology. 2018;16:71.

Article  PubMed  PubMed Central  Google Scholar 

Gebeshuber IC, Khawas S, Sharma R, Sharma N. Bioprinted scaffolds for biomimetic applications: a state-of-the-art technology. Biomimetics Basel. 2025. https://doi.org/10.3390/biomimetics10090595.

Article  PubMed  PubMed Central  Google Scholar 

Dawi J, Tumanyan K, Tomas K, Misakyan Y, Gargaloyan A, Gonzalez E, et al. Diabetic foot ulcers: pathophysiology, immune dysregulation, and emerging therapeutic strategies. Biomedicines. 2025. https://doi.org/10.3390/biomedicines13051076.

Article  PubMed  PubMed Central  Google Scholar 

Raziyeva K, Kim Y, Zharkinbekov Z, Kassymbek K, Jimi S, Saparov A. Immunology of acute and chronic wound healing. Biomolecules. 2021. https://doi.org/10.3390/biom11050700.

Article  PubMed  PubMed Central  Google Scholar 

Vaibhav, Nishad SS, Dongare D, Tripathi ACP, Tripathi T, Tripathi P. Deciphering the intricacies of immune system dysfunction and its impact on diabetes mellitus: Revisiting the communication strategies to manage diabetes mellitus. Health Sci Rev (Oxf). 2024;13:100201.

Google Scholar 

Holzer-Geissler JCJ, Schwingenschuh S, Zacharias M, Einsiedler J, Kainz S, Reisenegger P, et al. The impact of prolonged inflammation on wound healing. Biomedicines. 2022. https://doi.org/10.3390/biomedicines10040856.

Article  PubMed  PubMed Central  Google Scholar 

Yang D-R, Wang M-Y, Zhang C-L, Wang Y. Endothelial dysfunction in vascular complications of diabetes: a comprehensive review of mechanisms and implications. Front Endocrinol (Lausanne). 2024;15:1359255.

Article  PubMed  PubMed Central  Google Scholar 

Peyter A-C, Armengaud J-B, Guillot E, Yzydorczyk C. Endothelial progenitor cells dysfunctions and cardiometabolic disorders: from mechanisms to therapeutic approaches. Int J Mol Sci. 2021. https://doi.org/10.3390/ijms22136667.

Article  PubMed  PubMed Central  Google Scholar 

Wang J, Song Y, Xie W, Zhao J, Wang Y, Yu W. Therapeutic angiogenesis based on injectable hydrogel for protein delivery in ischemic heart disease. iScience. 2023;26:106577.

Article  CAS  PubMed  PubMed Central  Google Scholar 

Zeng J, Pan Y, Chaker SC, Torres-Guzman R, Lineaweaver WC, Qi F. Neural and inflammatory interactions in wound healing. Ann Plast Surg. 2024;93:S91-7.

Article  CAS  PubMed  Google Scholar 

Theocharidis G, Veves A. Autonomic nerve dysfunction and impaired diabetic wound healing: the role of neuropeptides. Auton Neurosci. 2020;223:102610.

Article  CAS  PubMed  Google Scholar 

Zheng S-Y, Wan X-X, Kambey PA, Luo Y, Hu X-M, Liu Y-F, et al. Therapeutic role of growth factors in treating diabetic wound. World J Diabetes. 2023;14:364–95.

Article  PubMed  PubMed Central  Google Scholar 

Smith J, Rai V. Novel factors regulating proliferation, migration, and differentiation of fibroblasts, keratinocytes, and vascular smooth muscle cells during wound healing. Biomedicines. 2024. https://doi.org/10.3390/biomedicines12091939.

Article  PubMed  PubMed Central  Google Scholar 

Chuliá-Peris L, Carreres-Rey C, Gabasa M, Alcaraz J, Carretero J, Pereda J. Matrix metalloproteinases and their inhibitors in pulmonary fibrosis: EMMPRIN/CD147 comes into play. Int J Mol Sci. 2022. https://doi.org/10.3390/ijms23136894.

Article  PubMed  PubMed Central  Google Scholar 

Daryabor G, Atashzar MR, Kabelitz D, Meri S, Kalantar K. The effects of Type 2 Diabetes Mellitus on organ metabolism and the immune system. Front Immunol. 2020;11:1582.

Article  CAS  PubMed  PubMed Central  Google Scholar 

Li Y, Liu Y, Liu S, Gao M, Wang W, Chen K, et al. Diabetic vascular diseases: molecular mechanisms and therapeutic strategies. Signal Transduct Target Ther. 2023;8:152.

Article  CAS  PubMed