World Health Organization. Fact sheet. Ageing and health. https://www.who.int/news-room/fact-sheets/detail/ageing-and-health

Tzeravini E, Tentolouris A, Kokkinos A, Tentolouris N, Katsilambros N. Diet induced thermogenesis, older and newer data with emphasis on obesity and diabetes mellitus-a narrative review. Metabolism Open. 2024;22:100291. https://doi.org/10.1016/j.metop.2024.100291.

Article  CAS  PubMed  PubMed Central  Google Scholar 

Roberts SB, Rosenberg I. Nutrition and aging: changes in the regulation of energy metabolism with aging. Physiol Rev. 2006;86(2):651–67. https://doi.org/10.1152/physrev.00019.2005.

Article  CAS  PubMed  Google Scholar 

Kinabo J, Durnin JVGA. Thermic effect of food in man: effect of meal composition, and energy content. Br J Nutr. 1990;64:37–44. https://doi.org/10.1079/bjn19900007.

Article  CAS  PubMed  Google Scholar 

Ho KK. Diet-induced thermogenesis: fake friend or foe? J Endocrinol. 2018;238:R185–91. https://doi.org/10.1530/JOE-18-0240.

Article  CAS  PubMed  Google Scholar 

Acheson K, Ravussin E, Wahren J, Jequier E. Thermic effect of glucose in man. Obligatory and facultative thermogenesis. J Clin Invest. 1984;74:1572–80. https://doi.org/10.1172/JCI111573.

Article  CAS  PubMed  PubMed Central  Google Scholar 

Brand MD, Chien L-F, Ainscow EK, Rolfe DF, Porter RK. The causes and functions of mitochondrial proton leak. Biochim Biophys Acta Bioenerg. 1994;1187:132–9. https://doi.org/10.1016/0005-2728(94)90099-x.

Article  CAS  Google Scholar 

Liesa M, Shirihai OS. Mitochondrial dynamics in the regulation of nutrient utilization and energy expenditure. Cell Metab. 2013;17:491–506. https://doi.org/10.1016/j.cmet.2013.03.002.

Article  CAS  PubMed  PubMed Central  Google Scholar 

Lanza IR, Nair KS. Mitochondrial function as a determinant of life span. Pflugers Arch. 2010;459:277–89. https://doi.org/10.1007/s00424-009-0724-5.

Article  CAS  PubMed  Google Scholar 

Boirie Y, Gachon P, Beaufrere B. Splanchnic and whole-body leucine kinetics in young and elderly men. Am J Clin Nutr. 1997;65:489–95. https://doi.org/10.1093/ajcn/65.2.489.

Article  CAS  PubMed  Google Scholar 

Huang H-H, Wang T-Y, Yao S-F, Lin P-Y, Chang JC-Y, Peng L-N, et al. Gastric mobility and gastrointestinal hormones in older patients with sarcopenia. Nutrients. 2022;14(9):1897. https://doi.org/10.3390/nu14091897.

Article  CAS  PubMed  PubMed Central  Google Scholar 

Kalyani RR, Egan JM. Diabetes and altered glucose metabolism with aging. Endocrinol Metab Clin North Am. 2013;42:333. https://doi.org/10.1016/j.ecl.2013.02.010.

Article  CAS  PubMed  PubMed Central  Google Scholar 

Volpi E, Mittendorfer B, Wolf SE, Wolfe RR. Oral amino acids stimulate muscle protein anabolism in the elderly despite higher first-pass splanchnic extraction. Am J Physiol Endocrinol Metab. 1999;277:E513–20. https://doi.org/10.1152/ajpendo.1999.277.3.E513.

Article  CAS  Google Scholar 

Melanson KJ, Saltzman E, Vinken AG, Russell R, Roberts SB. The effects of age on postprandial thermogenesis at four graded energetic challenges: findings in young and older women. J Gerontol Biol Sci Med Sci. 1998;53:B409–14. https://doi.org/10.1093/gerona/53a.6.b409.

Article  CAS  Google Scholar 

Westerterp KR. Diet induced thermogenesis. Nutr Metab (Lond). 2004;1:5. https://doi.org/10.1186/1743-7075-1-5.

Article  CAS  PubMed  PubMed Central  Google Scholar 

Bloesch D, Schutz Y, Breitenstein E, Jequier E, Felber J. Thermogenic response to an oral glucose load in man: comparison between young and elderly subjects. J Am Coll Nutr. 1988;7:471–83. https://doi.org/10.1080/07315724.1988.10720263.

Article  CAS  PubMed  Google Scholar 

Das SK, Moriguti JC, McCrory MA, Saltzman E, Mosunic C, Greenberg AS, et al. An underfeeding study in healthy men and women provides further evidence of impaired regulation of energy expenditure in old age. J Nutr. 2001;131:1833–8. https://doi.org/10.1093/jn/131.6.1833.

Article  CAS  PubMed  Google Scholar 

Du S, Rajjo T, Santosa S, Jensen MD. The thermic effect of food is reduced in older adults. Horm Metab Res. 2014;46:365–9. https://doi.org/10.1055/s-0033-1357205.

Article  CAS  PubMed  Google Scholar 

Fukagawa NK, Bandini LG, Lim P, Roingeard F, Lee M, Young JB. Protein-induced changes in energy expenditure in young and old individuals. Am J Physiol Endocrinol Metab. 1991;260:E345–52. https://doi.org/10.1152/ajpendo.1991.260.3.E345.

Article  CAS  Google Scholar 

Golay A, Schutz Y, Broquet C, Moeri R, Felber J, Jequier E. Decreased thermogenic response to an oral glucose load in older subjects. J Am Geriatr Soc. 1983;31:144–8. https://doi.org/10.1111/j.1532-5415.1983.tb04853.x.

Article  CAS  PubMed  Google Scholar 

Jones PP, Van Pelt RE, Johnson DG, Seals DR. Role of sympathetic neural activation in age-and habitual exercise-related differences in the thermic effect of food. J Clin Endocrinol Metab. 2004;89:5138–44. https://doi.org/10.1210/jc.2004-0101.

Article  CAS  PubMed  Google Scholar 

Morgan JB, York DA. Thermic effect of feeding in relation to energy balance in elderly men. Ann Nutr Metab. 1983;27:71–7. https://doi.org/10.1159/000176625.

Article  CAS  PubMed  Google Scholar 

Poehlman ET, Melby CL, Badylak SF. Relation of age and physical exercise status on metabolic rate in younger and older healthy men. J Gerontol. 1991;46:B54–8. https://doi.org/10.1093/geronj/46.2.b54.

Article  CAS  PubMed  Google Scholar 

Schwartz RS, Jaeger LF, Veith RC. The thermic effect of feeding in older men: the importance of the sympathetic nervous system. Metabolism. 1990;39:733–7. https://doi.org/10.1016/0026-0495(90)90109-p.

Article  CAS  PubMed  Google Scholar 

Thörne A, Wahren J. Diminished meal-induced thermogenesis in elderly man. Clin Physiol. 1990;10:427–37. https://doi.org/10.1111/j.1475-097x.1990.tb00823.x.

Article  PubMed  Google Scholar 

Tuttle W, Horvath S, Presson L, Daum K. Specific dynamic action of protein in men past 60 years of age. J Appl Physiol. 1953;5(10):631–6. https://doi.org/10.1152/jappl.1953.5.10.631.

Article  CAS  PubMed  Google Scholar 

Vaughan L, Zurlo F, Ravussin E. Aging and energy expenditure. Am J Clin Nutr. 1991;53(4):821–5. https://doi.org/10.1093/ajcn/53.4.821.

Article  CAS  PubMed  Google Scholar 

Visser M, Deurenberg P, van Staveren WA, Hautvast JG. Resting metabolic rate and diet-induced thermogenesis in young and elderly subjects: relationship with body composition, fat distribution, and physical activity level. Am J Clin Nutr. 1995;61:772–8. https://doi.org/10.1093/ajcn/61.4.772.

Article  CAS  PubMed  Google Scholar 

Belko A, Barbieri T, Wong E. Effect of energy and protein intake and exercise intensity on the thermic effect of food. Am J Clin Nutr. 1986;43:863–9. https://doi.org/10.1093/ajcn/43.6.863.

Article  CAS  PubMed