Crucial Roles of Electricity in Virology

Goetzinger KR, Rao VB (2003) Defining the ATPase centre of bacteriophage T4 DNA packaging machine: Requirement for a catalytic glutamate residue in the large terminase protein gp17. J Mol Biol 331:139–154

Article  CAS  PubMed  Google Scholar 

Migliori AD, Keller N, Alam TI, Mahalingam M, Rao VB, Arya G, Smith DE (2014) Evidence for an electrostatic mechanism of force generation by the bacteriophage T4 DNA packaging motor. Nat Commun 5:4173

Article  CAS  PubMed  Google Scholar 

Ordyan M, Alam I, Mahalingam M, Rao VB, Smith DE (2018) Nucleotide-dependent DNA gripping and an end-clamp mechanism regulate the bacteriophage T4 viral packaging motor. Nat Commun 9:5434

Article  CAS  PubMed  PubMed Central  Google Scholar 

Pajak J, Atz R, Hilbert BJ, Morais MC, Kelch BA, Jardine PJ, Arya G (2021) Viral packaging ATPases utilize a glutamate switch to couple ATPase activity and DNA translocation. Proc Natl Acad Sci USA 118:e2024928118

Article  CAS  PubMed  PubMed Central  Google Scholar 

Sun S, Kondabagil K, Gentz PM, Rossmann MG, Rao VB (2007) The structure of the ATPase that powers DNA packaging into bacteriophage T4 procapsids. Mol Cell 25:943–949

Article  CAS  PubMed  Google Scholar 

Sun S, Kondabagil K, Draper B, Alam TI, Bowman VD, Zhang Z, Hegde S, Fokine A, Rossmann MG, Rao VB (2008) The structure of the phage T4 DNA packaging motor suggests a mechanism dependent on electrostatic forces. Cell 135:1251–1262

Article  CAS  PubMed  Google Scholar 

Williams RS, Williams GJ, Tainer JA (2008) A charged performance by gp17 in viral packaging. Cell 135:1169. (2008)

Article  CAS  PubMed  Google Scholar 

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