Abdul-Aziz Ahmed K, Jabbar AAJ, Abdulla MA, Zuhair Alamri Z, Ain Salehen N, Abdel Aziz Ibrahim I, Almaimani G, Bamagous GA, Almaimani RA, Almasmoum HA, Ghaith MM, Farrash WF (2024) Mangiferin (mango) attenuates AOM-induced colorectal cancer in rat’s colon by augmentation of apoptotic proteins and antioxidant mechanisms. Sci Rep 14:813. https://doi.org/10.1038/s41598-023-50947-y
Article CAS PubMed PubMed Central Google Scholar
Abduljabbar AA, Abdoulrahman KK (2018) Allium Cepa) and garlic (Allium Sativa L,) oil effects on blood glucose levels and body weight of local quails in Erbil Province. Zanco J Pure Appl Sci 30:158–167. https://doi.org/10.21271/zjpas.30.5.14
Abood WN, Al-Henhena NA, Abood AN, Jamil Al-Obaidi MM, Ismail S, Abdulla MA, Al Batran R (2015) Wound-healing potential of the fruit extract of phaleria macrocarpa. Bosn J Basic Med Sci 15. https://doi.org/10.17305/bjbms.2015.39
Abood WN, Bradosty SW, Shaikh FK, Salehen NA, Farghadani R, Agha NFS, Al-Medhtiy MH, Kamil TDA, Agha AS, Abdulla MA (2020) Garcinia mangostana peel extracts exhibit hepatoprotective activity against thioacetamide-induced liver cirrhosis in rats. J Funct Foods 74. https://doi.org/10.1016/j.jff.2020.104200
Ahmed KA-A, Jabbar AAj, Raouf MMHM, Al-Qaaneh AM, Mothana RA, Alanzi AR, Abdullah FO, hassan RR, Abdulla MA, Saleh MI, Hasson S (2024a) A A bitter flavonoid gum from Dorema Aucheri accelerate wound healing in rats: involvement of Bax/HSP 70 and hydroxyprolin mechanisms. Ski Res Technol 30:e13896. https://doi.org/10.1111/srt.13896
Ahmed KA-A, Jabbar AAJ, Al-Qaaneh MRMMH, Mothana AM, Alanzi RA, Abdullah AR, Abdulla FO, Hasson MA, Zainel S (2024b) MA, c Wood calamint ameliorates ethanol-induced stomach injury in rats by augmentation of hsp/bax and inflammatory mechanisms. J. Mol. Histol. https://doi.org/10.1007/s10735-024-10211-7
Ahmed KA-A, Jabbar AAJ, Galali Y, Al-Qaaneh M, Akçakavak A, Salehen G, Hassan NA, Mothana RR, Abdulla RA, Fantoukh MA, Hasson OI, Hawwal S MF, 2024b cumin (Cuminum cyminum L.) seeds accelerates wound healing in rats: possible molecular mechanisms. Ski Res Technol 30:e13727. https://doi.org/10.1111/srt.13727
Aitcheson SM, Frentiu FD, Hurn SE, Edwards K, Murray RZ (2021) Skin wound healing: normal macrophage function and macrophage dysfunction in diabetic wounds. Molecules 26:4917
Article CAS PubMed PubMed Central Google Scholar
Al-Medhtiy MH, Mohammed MT, Raouf MMHM, Al-Qaaneh AM, Salih MI, Hassan RR, Hassan AO, Abdulla MA, Mamand SF, Ameen MM (2024) B Ephedra Intermedia alleviates ethanol-mediated gastric ulcer in rats by anti-inflammatory and antioxidant mechanisms. Baghdad Sci. J
Al-Medhtiy MH, Mohammed MT, Raouf M, Al-Qaaneh MMH, Jabbar AM, Abdullah AAj, Mothana FO, Alanzi RA, Hassan AR, Abdulla RR, Hasson MA S, 2024a A triterpenoid (corosolic acid) ameliorated AOM-mediated aberrant crypt foci in rats: modulation of Bax/PCNA, antioxidant and inflammatory mechanisms. J. Mol. Histol. https://doi.org/10.1007/s10735-024-10229-x
Al-Qaisi T, Al-Rawadeih S, Alsarayreh A, Qaisi Y, Al, Al-limoun M, Alqaraleh M, Khleifat K (2024) The effects of Anchusa azurea methanolic extract on burn wound healing: histological, antioxidant, and anti-inflammatory evaluation. https://doi.org/10.1016/j.burns.2024.05.001. Burns
Al-qaisi TS, Jabbar AAJ, Ubeid MH, Al-qaaneh AM, Mothana RA, Hawwal MF, Hassan RR, Abdulla MA, Saleh MI 2024 hepatotoxicity in animal model: role of PCNA / Bax, oxidative stress, and inflammatory cytokines open Access. Ital J Food Sci 36:208–228. https://doi.org/10.15586/ijfs.v36i4.2723
Alkreathy HM, Esmat A (2022) Ameliorates Thioacetamide-Induced hepatic fibrosis in rats: emphasis on Antioxidant, anti-inflammatory, and STAT3 inhibition effects. Pharmaceuticals 15. https://doi.org/10.3390/ph15030369
Almaimani G, Jabbar AAJ, Ibrahim IAA, Alzahrani AR, Bamagous GA, Almaimani RA, Almasmoum HA, Ghaith MM, Farrash WF, Azlina MFN (2024) Pimpinella anisum L.) attenuates azoxymethane-induced colorectal cancer by antioxidant, anti-inflammatory, and anti-apoptotic pathways in rats. Environ Sci Pollut Res 31:4439–4452. https://doi.org/10.1007/s11356-023-31349-z
Ashry OM, Hussein EM, Abd El-Azime ASH (2017) Restorative role of persimmon leaf (Diospyros kaki) to gamma irradiation-induced oxidative stress and tissue injury in rats. Int J Radiat Biol 93:324–329. https://doi.org/10.1080/09553002.2016.1254831
Article CAS PubMed Google Scholar
Bei W, Zang L, Guo J, Peng W, Xu A, Good DA, Hu Y, Wu W, Hu D, Zhu X (2009) Neuroprotective effects of a standardized flavonoid extract from Diospyros kaki leaves. J Ethnopharmacol 126:134–142
Article CAS PubMed Google Scholar
Budovsky A, Yarmolinsky L, Ben-Shabat S (2015) Effect of medicinal plants on wound healing. Wound Repair Regen 23:171–183. https://doi.org/10.1111/wrr.12274
Carvalheiro T, Malvar Fernández B, Ottria A, Giovannone B, Marut W, Reedquist KA, Garcia S, Radstake TR 2020 Extracellular SPARC cooperates with TGF-β signalling to induce pro-fibrotic activation of systemic sclerosis patient dermal fibroblasts. Rheumatology 59:2258–2263
Chang Y-L, Lin J-T, Lin H-L, Liao P-L, Wu P-J, Yang D-J 2019 phenolic compositions and antioxidant properties of leaves of eight persimmon varieties harvested in different periods. Food Chem 289:74–83
Chen G, Xue J, Xu S-X, Zhang R-Q (2007) Chemical constituents of the leaves of Diospyros kaki and their cytotoxic effects. J Asian Nat Prod Res 9:347–353
Article CAS PubMed Google Scholar
Cho C-W, Song Y-R, Hwang Y-H, Rhee YK, Lim W-C, Choi JW, Lee K-T, Hong H-D 2021 in vitro genotoxicity and in vivo single-dose oral toxicity of polysaccharide fraction from the leaves of Diospyros kaki Thunb. Pharmacogn Mag 17
Direito R, Rocha J, Serra A-T, Fernandes A, Freitas M, Fernandes E, Pinto R, Bronze R, Sepodes B, Figueira M-E (2020) Anti-inflammatory effects of persimmon (Diospyros kaki L.) in experimental rodent rheumatoid arthritis. J Diet Suppl 17:663–683
Article CAS PubMed Google Scholar
Direito R, Rocha J, Sepodes B, Eduardo-Figueira M (2021) From Diospyros kaki L. (Persimmon) Phytochemical Profile and Health Impact to New Product Perspectives and Waste Valorization. Nutrients 13. https://doi.org/10.3390/nu13093283
Dong Y, Yu X, Ye X, Gao Z, Wang S, Qu S 2022 current status and perspective of persimmon research in China. Technol Hortic 2:1–10
Fathi FM, Harita H, Mahmood AA, Suzy SM, Salmah I, Zahra AA, Kamal K (2014) Acceleration of wound healing activity by Polygonatum odoratum leaf extract in rats. J Med Plants Res 8:523–528
Gao X, Zhang Z, Wang X, Qian J, Hu L, Li Z, Li W (2023) Studies of value in use, chemical compositions, biological and pharmacological activities, and quality control of Rubus berries: a comprehensive review. J Food Compos Anal 124:105707. https://doi.org/10.1016/j.jfca.2023.105707
Guideline O 423:, 2001 Acute oral toxicity-acute toxic class method. OECD guidelines for the testing of Chemicals. OECD Publishing, Paris
Ham Y-M, Yoon S-A, Hyun HB, Go B, Jung Y-H, Oh D-J, Yoon W-J 2020 Genotoxicity Study of Immature Green Persimmon Extract. J Food Hyg Saf 35:567–573
Hwang Y-H, Ha H, Kim R, Cho C-W, Song Y-R, Hong H-D, Kim T (2018) Anti-osteoporotic effects of polysaccharides isolated from persimmon leaves via osteoclastogenesis inhibition. Nutrients 10:901
Article PubMed PubMed Central Google Scholar
Jabbar AAJ, Alamri ZZ (2024) Toxicity and Hepatoprotective Influence of Hypericum perforatum against Thioactamid-Induced Liver fibrosis in rats. Nat Prod Commun 19:1934578X241250243. https://doi.org/10.1177/1934578X241250243
Jabbar AA, Ibrahim IAA, Abdullah FO, Aziz KF, Alzahrani AR, Abdulla MA (2023a) Chemopreventive effects of Onosma Mutabilis against Azoxymethane-Induced Colon cancer in rats via amendment of Bax/Bcl-2 and NF-κB signaling pathways. Curr Issues Mol Biol 45:885–902
Article CAS PubMed PubMed Central Google Scholar
Jabbar AAj, Alamri ZZ, Abdulla MA, Salehen NA, Sinawi SAA, Alfaifi Z, SM (2023b) Hepatoprotective effects of Gynura procumbens against thioacetamide-induced cirrhosis in rats: targeting inflammatory and oxidative stress signalling pathways. Heliyon 9:e19418. https://doi.org/10.1016/j.heliyon.2023.e19418
Article CAS PubMed PubMed Central Google Scholar
Jabbar AAj, Ahmed A-A, Abdulla K, Abdullah MA, Salehen FO, Mothana NA, Houssaini RA, Hassan J, Hawwal RR, Fantoukh MF, Hasson OI, S (2024) Sinomenine accelerate wound healing in rats by augmentation of antioxidant, anti-inflammatory, immunuhistochemical pathways. Heliyon 10:e23581. https://doi.org/10.1016/j.heliyon.2023.e23581
Article CAS PubMed Google Scholar
Jeon IH, Kang HJ, Lee H-S, Shin JH, Park YG, Jeong S-I, Jang S, Il (2014) Antioxidant and anti-inflammatory activities of water-soluble extracts from different parts of Kojongsi Persimmon (Diospyros kaki L). Korean J Food Sci Technol 46:505–510
Jinpeng C, ZHANG K, Yi LIU, Song JIN, Xiaohong GAI, Tao REN, Chengwang T (2022) Efficacy of phospholipid complex of flavonoids from persimmon leaves on atherosclerosis, and possible mechanism. J Tradit Chin Med 42:417
Khlaywi SA, AL-Taweel AA, Alrubeai HF, Mezban AA, SEASONAL OCCURRENCE OF THE MEDITERRANEAN FRUIT FLY, CERATITIS CAPITATA IN SOME ORCHARDS OF CENTRAL AND SOUTHERN REGION OF IRAQ (2020) Plant Arch 20:3972–3976
Las Heras K, Igartua M, Santos-Vizcaino E, Hernandez RM (2020) Chronic wounds: current status, available strategies and emerging therapeutic solutions. J Control Release 328:532–550
Article CAS PubMed Google Scholar
Lee S-G, Jung J-Y, Shin J-S, Shin K-S, Cho C-W, Rhee Y-K, Hong H-D, Lee K-T 2015 Immunostimulatory polysaccharide isolated from the leaves of Diospyros kaki Thumb modulate macrophage via TLR2. Int J Biol Macromol 79:971–982
Lim W-C, Choi JW, Song N-E, Cho C-W, Rhee YK, Hong H-D (2020) Polysaccharide isolated from persimmon leaves (Diospyros kaki Thunb.) Suppresses TGF-β1-induced epithelial-to-mesenchymal transition in A549 cells. Int J Biol Macromol 164:3835–3845. https://doi.org/10.1016/j.ijbiomac.2020.08.155
Article CAS PubMed Google Scholar
Liu J, Zhang J, Lin X, Boyce BF, Zhang H, Xing L (2022) Age-associated callus senescent cells produce TGF-β1 that inhibits fracture healing in aged mice. J Clin Invest 132. https://doi.org/10.1172/JCI148073
Lv Y-W, Du Y, Ma S-S, Shi Y-C, Xu H-C, Deng L, Chen X-Y 2023 proanthocyanidins attenuates ferroptosis against influenza-induced acute lung injury in mice by reducing IFN-γ. Life Sci 314:121279. https://doi.org/10.1016/j.lfs.2022.121279
Mantle D, Gok MA, Lennard TW (2001) Adverse and beneficial effects of plant extracts on skin and skin disorders. Adverse Drug React Toxicol Rev 20:89–103
Nussbaum SR, Carter MJ, Fife CE, DaVanzo J, Haught R, Nusgart M, Cartwright D (2018) An economic evaluation of the impact, cost, and medicare policy implications of chronic nonhealing wounds. Value Heal 21:27–32
Percie du Sert N, Hurst V, Ahluwalia A, Alam S, Avey MT, Baker M, Browne WJ, Clark A, Cuthill IC, Dirnagl U, Emerson M, Garner P, Holgate ST, Howells DW, Karp NA, Lazic SE, Lidster K, MacCallum CJ, Macleod M, Pearl EJ, Petersen OH, Rawle F, Reynolds, Würbel H P, Rooney, K, Sena, ES, Silberberg, SD, Steckler, T, 2020 the ARRIVE guidelines 2.0: updated guidelines for reporting animal research. BMC Vet Res 16:242. https://doi.org/10.1186/s12917-020-02451-y
Petrova M, Dimitrova L, Dimitrova M, Denev P, Teneva D, Georgieva A, Petkova-Kirova P, Lazarova M, Tasheva K (2023) Antitumor and antioxidant activities of in Vitro cultivated and wild-growing Clinopodium vulgare L. Plants Plants. https://doi.org/10.3390/plants12081591
Polerà N, Badolato M, Perri F, Carullo G, Aiello F (2019) Quercetin and its natural sources in wound healing management. Curr Med Chem 26:5825–5848
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