Claahsen-van der Grinten, H. L. et al. Congenital adrenal hyperplasia-current insights in pathophysiology, diagnostics, and management. Endocr. Rev. 43, 91–159 (2022).

Article  PubMed  Google Scholar 

Auer, M. K., Nordenström, A., Lajic, S. & Reisch, N. Congenital adrenal hyperplasia. Lancet 401, 227–244 (2023).

Article  PubMed  CAS  Google Scholar 

Whitaker, M. J., Huatan, H. & Ross, R. J. Chronotherapy based on modified-release hydrocortisone to restore the physiological cortisol diurnal rhythm. Drug Deliv. Transl. Res. 13, 1–8 (2023).

Article  PubMed  CAS  Google Scholar 

Auchus, R. J. et al. Phase 3 trial of crinecerfont in adult congenital adrenal hyperplasia. N. Engl. J. Med. 391, 504–514 (2024).

Article  PubMed  PubMed Central  CAS  Google Scholar 

Sarafoglou, K. et al. Phase 3 trial of crinecerfont in pediatric congenital adrenal hyperplasia. N. Engl. J. Med. 391, 493–503 (2024).

Article  PubMed  CAS  Google Scholar 

Domin, H. & Śmiałowska, M. The diverse role of corticotropin-releasing factor (CRF) and its CRF1 and CRF2 receptors under pathophysiological conditions: Insights into stress/anxiety, depression, and brain injury processes. Neurosci. Biobehav. Rev. 163, 105748 (2024).

Article  PubMed  CAS  Google Scholar 

Lawrence, S. & Scofield, R. H. Post traumatic stress disorder associated hypothalamic-pituitary-adrenal axis dysregulation and physical illness. Brain Behav. Immun. Health 41, 100849 (2024).

Article  PubMed  PubMed Central  CAS  Google Scholar 

Pandey, G. N., Rizavi, H. S., Bhaumik, R. & Ren, X. Increased protein and mRNA expression of corticotropin-releasing factor (CRF), decreased CRF receptors and CRF binding protein in specific postmortem brain areas of teenage suicide subjects. Psychoneuroendocrinology 106, 233–243 (2019).

Article  PubMed  PubMed Central  CAS  Google Scholar 

Mantsch, J. R. Corticotropin releasing factor and drug seeking in substance use disorders: preclinical evidence and translational limitations. Addict. Neurosci. 4, 100038 (2022).

Article  PubMed  PubMed Central  Google Scholar 

Ibarguen-Vargas, Y., Leman, S., Palme, R., Belzung, C. & Surget, A. CRF-R1 antagonist treatment exacerbates circadian corticosterone secretion under chronic stress, but preserves HPA feedback sensitivity. Pharmaceutics 13, 2114 (2021).

Article  PubMed  PubMed Central  CAS  Google Scholar