Kakeji Y, Takahashi A, Hasegawa H, Ueno H, Eguchi S, Endo I, et al. Surgical outcomes in gastroenterological surgery in Japan: report of the National Clinical Database 2011–2018. Ann Gastroenterol Surg. 2020;4:250–74.

Article  PubMed  PubMed Central  Google Scholar 

Soerjomataram I, Bray F. Planning for tomorrow: global cancer incidence and the role of prevention 2020–2070. Nat Rev Clin Oncol. 2021;18:663–72.

Article  PubMed  Google Scholar 

Sung H, Ferlay J, Siegel RL, Laversanne M, Soerjomataram I, Jemal A, et al. Global cancer statistics 2020: GLOBOCAN estimates of incidence and mortality worldwide for 36 cancers in 185 countries. CA Cancer J Clin. 2021;71:209–49.

Article  PubMed  Google Scholar 

Rockwood K, Mitnitski A. Frailty in relation to the accumulation of deficits. J Gerontol A Biol Sci Med Sci. 2007;62:722–7.

Article  PubMed  Google Scholar 

Bunt S, Steverink N, Olthof J, van der Schans CP, Hobbelen JSM. Social frailty in older adults: a scoping review. Eur J Ageing. 2017;14:323–34.

Article  CAS  PubMed  PubMed Central  Google Scholar 

Sugimoto T, Arai H, Sakurai T. An update on cognitive frailty: its definition, impact, associated factors and underlying mechanisms, and interventions. Geriatr Gerontol Int. 2022;22:99–109.

Article  PubMed  Google Scholar 

Lee DU, Kwon J, Han J, Fan GH, Hastie DJ, Lee KJ, et al. The clinical impact of frailty on the postoperative outcomes of patients undergoing gastrectomy for gastric cancer: a propensity-score matched database study. Gastric Cancer. 2022;25:450–8.

Article  PubMed  Google Scholar 

Sakurai K, Kubo N, Hasegawa T, Tamamori Y, Kuroda K, Iseki Y, et al. Risk factors of “loss of independence” in elderly patients who received gastrectomy for gastric cancer. Gastric Cancer. 2023;26:638–47.

Article  PubMed  Google Scholar 

Tan ZK, Tang WZ, Jia K, Li DN, Qiu LY, Chen X, et al. Relation between frailty and adverse outcomes in elderly patients with gastric cancer: a scoping review. Ann Med Surg (Lond). 2024;86:1590–600.

PubMed  Google Scholar 

Osaki T, Saito H, Miyauchi W, Shishido Y, Miyatani K, Matsunaga T, et al. The type of gastrectomy and modified frailty index as useful predictive indicators for 1-year readmission due to nutritional difficulty in patients who undergo gastrectomy for gastric cancer. BMC Surg. 2021;21:445.

Article  PubMed  PubMed Central  Google Scholar 

Japanese Gastric Cancer A. Japanese gastric cancer treatment guidelines 2018 (5th edition). Gastric Cancer. 2018;2021(24):1–21.

Google Scholar 

Joseph B, Pandit V, Zangbar B, Kulvatunyou N, Hashmi A, Green DJ, et al. Superiority of frailty over age in predicting outcomes among geriatric trauma patients: a prospective analysis. JAMA Surg. 2014;149:766–72.

Article  PubMed  Google Scholar 

Clavien PA, Barkun J, de Oliveira ML, Vauthey JN, Dindo D, Schulick RD, et al. The Clavien-Dindo classification of surgical complications: five-year experience. Ann Surg. 2009;250:187–96.

Article  PubMed  Google Scholar 

Pallis AG, Wedding U, Lacombe D, Soubeyran P, Wildiers H. Questionnaires and instruments for a multidimensional assessment of the older cancer patient: what clinicians need to know? Eur J Cancer. 2010;46:1019–25.

Article  CAS  PubMed  Google Scholar 

Dasgupta M, Rolfson DB, Stolee P, Borrie MJ, Speechley M. Frailty is associated with postoperative complications in older adults with medical problems. Arch Gerontol Geriatr. 2009;48:78–83.

Article  PubMed  Google Scholar 

Robinson TN, Eiseman B, Wallace JI, Church SD, McFann KK, Pfister SM, et al. Redefining geriatric preoperative assessment using frailty, disability and co-morbidity. Ann Surg. 2009;250:449–55.

Article  PubMed  Google Scholar 

Revenig LM, Canter DJ, Kim S, Liu Y, Sweeney JF, Sarmiento JM, et al. Report of a simplified frailty score predictive of short-term postoperative morbidity and mortality. J Am Coll Surg. 2015;220:904-11.e1.

Article  PubMed  Google Scholar 

Choe YR, Joh JY, Kim YP. Association between frailty and readmission within one year after gastrectomy in older patients with gastric cancer. J Geriatr Oncol. 2017;8:185–9.

Article  PubMed  Google Scholar 

Osaki T, Saito H, Shimizu S, Murakami Y, Miyatani K, Matsunaga T, et al. Modified frailty index is useful in predicting non-home discharge in elderly patients with gastric cancer who undergo gastrectomy. World J Surg. 2020;44:3837–44.

Article  PubMed  Google Scholar 

Ogawa M, Satomi-Kobayashi S, Yoshida N, Komaki K, Izawa KP, Hamaguchi M, et al. Impact of frailty on postoperative dysphagia in patients undergoing elective cardiovascular surgery. JACC Asia. 2022;2:104–13.

Article  PubMed  PubMed Central  Google Scholar 

Sakurai K, Kubo N, Hasegawa T, Nishimura J, Iseki Y, Nishii T, et al. The development of a risk assessment tool for patients with postoperative pneumonia after gastrectomy for gastric cancer. J Gastrointest Surg. 2024;28:359–64.

Article  PubMed  Google Scholar 

Cho H, Tsuchida K, Iwasaki K, Maezawa Y. Risk factors of post-operative pneumonia in elderly patients with gastric cancer: a retrospective cohort study. Jpn J Clin Oncol. 2021;51:1044–50.

Article  PubMed  Google Scholar 

Yoshida K, Honda M, Kumamaru H, Kodera Y, Kakeji Y, Hiki N, et al. Surgical outcomes of laparoscopic distal gastrectomy compared to open distal gastrectomy: a retrospective cohort study based on a nationwide registry database in Japan. Ann Gastroenterol Surg. 2018;2:55–64.

Article  PubMed  Google Scholar 

Kodera Y, Yoshida K, Kumamaru H, Kakeji Y, Hiki N, Etoh T, et al. Introducing laparoscopic total gastrectomy for gastric cancer in general practice: a retrospective cohort study based on a nationwide registry database in Japan. Gastric Cancer. 2019;22:202–13.

Article  PubMed  Google Scholar 

Arakawa H, Komatsu S, Kamiya H, Nishibeppu K, Ohashi T, Konishi H, et al. Differences of clinical features and outcomes between male and female elderly patients in gastric cancer. Sci Rep. 2023;13:17192.

Article  CAS  PubMed  PubMed Central  Google Scholar 

Baimas-George M, Watson M, Elhage S, Parala-Metz A, Vrochides D, Davis BR. Prehabilitation in frail surgical patients: a systematic review. World J Surg. 2020;44:3668–78.

Article  PubMed  Google Scholar 

Barberan-Garcia A, Ubré M, Roca J, Lacy AM, Burgos F, Risco R, et al. Personalised prehabilitation in high-risk patients undergoing elective major abdominal surgery: a randomized blinded controlled trial. Ann Surg. 2018;267:50–6.

Article  PubMed  Google Scholar 

Berkel AEM, Bongers BC, Kotte H, Weltevreden P, de Jongh FHC, Eijsvogel MMM, et al. Effects of community-based exercise prehabilitation for patients scheduled for colorectal surgery with high risk for postoperative complications: results of a randomized clinical trial. Ann Surg. 2022;275:e299–306.

Article  PubMed  Google Scholar 

Bausys A, Luksta M, Anglickiene G, Maneikiene VV, Kryzauskas M, Rybakovas A, et al. Effect of home-based prehabilitation on postoperative complications after surgery for gastric cancer: randomized clinical trial. Br J Surg. 2023;110:1800–7.

Article  PubMed  Google Scholar 

Fried LP, Tangen CM, Walston J, Newman AB, Hirsch C, Gottdiener J, et al. Frailty in older adults: evidence for a phenotype. J Gerontol A Biol Sci Med Sci. 2001;56:M146–56.

Article  CAS  PubMed  Google Scholar 

Rockwood K, Song X, MacKnight C, Bergman H, Hogan DB, McDowell I, et al. A global clinical measure of fitness and frailty in elderly people. CMAJ. 2005;173:489–95.

Article  PubMed  PubMed Central  Google Scholar