Huang K, Huang X, Qian S, Cai Y, Wu F et al (2024) Temporal trends of thyroid cancer in China and globally from 1990 to 2021: an analysis of the global burden of disease study 2021. Sci Rep 14:25538. https://doi.org/10.1038/s41598-024-77663-5
Article CAS PubMed PubMed Central Google Scholar
Volpe F, Nappi C, Zampella E, Di Donna E, Maurea S et al (2024) Current advances in radioactive Iodine-Refractory differentiated thyroid Cancer. Curr Oncol 31:3870–3884. https://doi.org/10.3390/curroncol31070286
Article PubMed PubMed Central Google Scholar
Haugen BR, Sherman SI (2013) Evolving approaches to patients with advanced differentiated thyroid cancer. Endocr Rev 34:439–455. https://doi.org/10.1210/er.2012-1038
Article CAS PubMed PubMed Central Google Scholar
Schlumberger M, Lacroix L, Russo D, Filetti S, Bidart JM (2007) Defects in iodide metabolism in thyroid cancer and implications for the follow-up and treatment of patients. Nat Clin Pract Endocrinol Metab 3:260–269. https://doi.org/10.1038/ncpendmet0449
Article CAS PubMed Google Scholar
Chan WWL, Chan S, Kwong DLW (2022) Radioiodine refractory differentiated thyroid Cancer. Methods Mol Biol 2534:243–257. https://doi.org/10.1007/978-1-0716-2505-7_17
Article CAS PubMed Google Scholar
Oh JM, Ahn BC (2021) Molecular mechanisms of radioactive iodine refractoriness in differentiated thyroid cancer: impaired sodium iodide symporter (NIS) expression owing to altered signaling pathway activity and intracellular localization of NIS. Theranostics 11:6251–6277. https://doi.org/10.7150/thno.57689
Article CAS PubMed PubMed Central Google Scholar
Liu Y, Wang J, Hu X, Pan Z, Xu T et al (2023) Radioiodine therapy in advanced differentiated thyroid cancer: resistance and overcoming strategy. Drug Resist Updat 68:100939. https://doi.org/10.1016/j.drup.2023.100939
Article CAS PubMed Google Scholar
Dratwa M, Wysoczańska B, Łacina P, Kubik T, Bogunia-Kubik K (2020) TERT-Regulation and roles in Cancer formation. Front Immunol 11:589929. https://doi.org/10.3389/fimmu.2020.589929
Article CAS PubMed PubMed Central Google Scholar
Lassmann T, Maida Y, Tomaru Y, Yasukawa M, Ando Y et al (2015) Telomerase reverse transcriptase regulates MicroRNAs. Int J Mol Sci 16:1192–1208. https://doi.org/10.3390/ijms16011192
Article CAS PubMed PubMed Central Google Scholar
Yasukawa M, Ando Y, Yamashita T, Matsuda Y, Shoji S et al (2020) CDK1 dependent phosphorylation of hTERT contributes to cancer progression. Nat Commun 11:1557. https://doi.org/10.1038/s41467-020-15289-7
Article CAS PubMed PubMed Central Google Scholar
Maida Y, Yasukawa M, Furuuchi M, Lassmann T, Possemato R et al (2009) An RNA-dependent RNA polymerase formed by TERT and the RMRP RNA. Nature 461:230–235. https://doi.org/10.1038/nature08283
Article CAS PubMed PubMed Central Google Scholar
Maida Y, Yasukawa M, Masutomi K (2016) De Novo RNA synthesis by RNA-Dependent RNA polymerase activity of telomerase reverse transcriptase. Mol Cell Biol 36:1248–1259. https://doi.org/10.1128/MCB.01021-15
Article CAS PubMed PubMed Central Google Scholar
Maida Y, Yasukawa M, Okamoto N, Ohka S, Kinoshita K et al (2014) Involvement of telomerase reverse transcriptase in heterochromatin maintenance. Mol Cell Biol 34:1576–1593. https://doi.org/10.1128/MCB.00093-14
Article CAS PubMed PubMed Central Google Scholar
Hay ID, Bergstralh EJ, Goellner JR, Ebersold JR, Grant CS (1993) Predicting outcome in papillary thyroid carcinoma: development of a reliable prognostic scoring system in a cohort of 1779 patients surgically treated at one institution during 1940 through 1989. Surgery 114:1050–1057
Chen C, Ridzon DA, Broomer AJ, Zhou Z, Lee DH et al (2005) Real-time quantification of MicroRNAs by stem-loop RT-PCR. Nucleic Acids Res 33:e179. https://doi.org/10.1093/nar/gni178
Article CAS PubMed PubMed Central Google Scholar
Shen H, Zhu R, Liu Y, Hong Y, Ge J et al (2024) Radioiodine-refractory differentiated thyroid cancer: molecular mechanisms and therapeutic strategies for radioiodine resistance. Drug Resist Updat 72:101013. https://doi.org/10.1016/j.drup.2023.101013
Article CAS PubMed Google Scholar
De la Vieja A, Santisteban P (2018) Role of iodide metabolism in physiology and cancer. Endocr Relat Cancer 25:R225–r245. https://doi.org/10.1530/ERC-17-0515
Benvenga S, Guarneri F (2018) Homology of Pendrin, sodium-iodide symporter and apical iodide transporter. Front Biosci (Landmark Ed) 23:1864–1873. https://doi.org/10.2741/4677
Article CAS PubMed Google Scholar
Liu J, Liu Y, Lin Y, Liang J (2019) Radioactive Iodine-Refractory differentiated thyroid Cancer and redifferentiation therapy. Endocrinol Metab (Seoul) 34:215–225. https://doi.org/10.3803/EnM.2019.34.3.215
Article CAS PubMed Google Scholar
Zhang L, Xu S, Cheng X, Wu J, Wang Y et al (2023) Inflammatory tumor microenvironment of thyroid cancer promotes cellular dedifferentiation and Silencing of iodide-handling genes expression. Pathol Res Pract 246:154495. https://doi.org/10.1016/j.prp.2023.154495
Article CAS PubMed Google Scholar
Machitani M, Yasukawa M, Nakashima J, Furuichi Y, Masutomi K (2020) RNA-dependent RNA polymerase, RdRP, a promising therapeutic target for cancer and potentially COVID-19. Cancer Sci 111:3976–3984. https://doi.org/10.1111/cas.14618
Article CAS PubMed PubMed Central Google Scholar
Cancer Genome Atlas Research Network (2014) Integrated genomic characterization of papillary thyroid carcinoma. Cell 159:676–690. https://doi.org/10.1016/j.cell.2014.09.050
Bhattacharya S, Mahato RK, Singh S, Bhatti GK, Mastana SS et al (2023) Advances and challenges in thyroid cancer: the interplay of genetic modulators, targeted therapies, and AI-driven approaches. Life Sci 332:122110. https://doi.org/10.1016/j.lfs.2023.122110
Article CAS PubMed Google Scholar
Colombo C, Minna E, Gargiuli C, Muzza M, Dugo M et al (2020) The molecular and gene/mirna expression profiles of radioiodine resistant papillary thyroid cancer. J Exp Clin Cancer Res 39:245. https://doi.org/10.1186/s13046-020-01757-x
Article CAS PubMed PubMed Central Google Scholar
Wang D, Liu X, Li M, Ning J (2024) HIF-1α regulates the cell viability in radioiodine-resistant papillary thyroid carcinoma cells induced by hypoxia through PKM2/NF-κB signaling pathway. Mol Carcinog 63:238–252. https://doi.org/10.1002/mc.23648
Article CAS PubMed Google Scholar
Matsuse M, Mitsutake N (2023) TERT promoter mutations in thyroid cancer. Endocr J 70:1035–1049. https://doi.org/10.1507/endocrj.EJ23-0136
Article CAS PubMed Google Scholar
Liu X, Bishop J, Shan Y, Pai S, Liu D et al (2013) Highly prevalent TERT promoter mutations in aggressive thyroid cancers. Endocr Relat Cancer 20:603–610. https://doi.org/10.1530/ERC-13-0210
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