A. Periferakis, G. Tsigas, A.T. Periferakis, C.M. Tone, D.A. Hemes, K. Periferakis et al. Agonists, antagonists and receptors of somatostatin: pathophysiological and therapeutical implications in neoplasias. Curr. Issues Mol. Biol. 46(9), 9721–9759 (2024)
Article CAS PubMed PubMed Central Google Scholar
U. Rai, T.R. Thrimawithana, C. Valery, S.A. Young, Therapeutic uses of somatostatin and its analogues: current view and potential applications. Pharmacol. Ther. 152, 98–110 (2015)
Article CAS PubMed Google Scholar
A. Angelousi, A. Koumarianou, E. Chatzellis, G. Kaltsas, Resistance of neuroendocrine tumours to somatostatin analogs. Expert Rev. Endocrinol. Metab. 18(1), 33–52 (2023)
Article CAS PubMed Google Scholar
A. Colao, R.S. Auriemma, R. Pivonello, L. Kasuki, M.R. Gadelha, Interpreting biochemical control response rates with first-generation somatostatin analogues in acromegaly. Pituitary 19(3), 235–247 (2016)
Article CAS PubMed Google Scholar
B. Kiesewetter, F.F. Pflüger, P. Melhorn, P. Mazal, M. Raderer, Long-term experience with octreotide and lanreotide for the treatment of gastroenteropancreatic neuroendocrine tumors. Clin. Transl. Oncol. 27(4), 1642–1652 (2025)
Article CAS PubMed Google Scholar
L.B. Anthony, T.M. O’Dorisio, Opportunities to improve symptom control with somatostatin congeners in GEP-NETs: a review of key issues. Oncologist 26(7), e1171–e1178 (2021)
Article PubMed PubMed Central Google Scholar
N. Brighi, F. Panzuto, R. Modica, F. Gelsomino, M. Albertelli, S. Pusceddu et al. Biliary stone disease in patients with neuroendocrine tumors treated with somatostatin analogs: a multicenter study. Oncologist 25(3), 259–265 (2020)
Article CAS PubMed Google Scholar
A.T. Scott, J.R. Howe, Evaluation and management of neuroendocrine tumors of the pancreas. Surg. Clin. North. Am. 99(4), 793–814 (2019)
Article PubMed PubMed Central Google Scholar
E. Liu, K.D. Hoffman, G. Murfin, H. Eccard, Breakthrough symptoms remain an unmet need in symptomatic patients with neuroendocrine tumors and carcinoid syndrome. Pancreas 52(1), e70–e74 (2023)
Article CAS PubMed Google Scholar
P. Ryan, A. McBride, D. Ray, S. Pulgar, R.A. Ramirez, E. Elquza et al. Lanreotide vs octreotide LAR for patients with advanced gastroenteropancreatic neuroendocrine tumors: an observational time and motion analysis. J. Oncol. Pharm. Pract. 25(6), 1425–1433 (2019)
Article CAS PubMed PubMed Central Google Scholar
C. Chen, B. Wu, C. Zhang, T. Xu, Immune-related adverse events associated with immune checkpoint inhibitors: an updated comprehensive disproportionality analysis of the FDA adverse event reporting system. Int. Immunopharmacol. 95, 107498 (2021)
Article CAS PubMed Google Scholar
Y. Wang, B. Zhao, H. Yang, Z. Wan, A real-world pharmacovigilance study of FDA adverse event reporting system events for sildenafil. Andrology 12(4), 785–792 (2024)
Article CAS PubMed Google Scholar
L. Wang, G. Jiang, D. Li, H. Liu, Standardizing adverse drug event reporting data. J. Biomed. Semantics. 5, 36 (2014)
Article PubMed PubMed Central Google Scholar
E.P. van Puijenbroek, A. Bate, H.G. Leufkens, M. Lindquist, R. Orre, A.C. Egberts, A comparison of measures of disproportionality for signal detection in spontaneous reporting systems for adverse drug reactions. Pharmacoepidemiol. Drug. Saf. 11(1), 3–10 (2002)
K. Kubota, D. Koide, T. Hirai, Comparison of data mining methodologies using Japanese spontaneous reports. Pharmacoepidemiol. Drug. Saf. 13(6), 387–394 (2004)
S.T. de Vries, P. Denig, C. Ekhart, P.G.M. Mol, E.P. van Puijenbroek, Sex differences in adverse drug reactions of metformin: a longitudinal survey study. Drug. Saf. 43(5), 489–495 (2020)
Article PubMed PubMed Central Google Scholar
C. Álvarez-Escolá, E.M. Venegas-Moreno, J.A. García-Arnés, C. Blanco-Carrera, M. Marazuela-Azpiroz, M. Gálvez-Moreno et al. ACROSTART: a retrospective study of the time to achieve hormonal control with lanreotide Autogel treatment in Spanish patients with acromegaly. Endocrinol. Diabetes Nutr. 66(5), 320–329 (2019)
P. Caron, [Somatuline(R) Autogel(R), a new formulation of lanreotide for the treatment of acromegalic patients]. Ann. Endocrinol. 63(2 Pt 3), 2s19–24s19 (2002)
A. Dasari, C. Shen, D. Halperin, B. Zhao, S. Zhou, Y. Xu et al. Trends in the incidence, prevalence, and survival outcomes in patients with neuroendocrine tumors in the United States. JAMA Oncol. 3(10), 1335–1342 (2017)
Article PubMed PubMed Central Google Scholar
D.L. Chan, D. Ferone, M. Albertelli, N. Pavlakis, E. Segelov, S. Singh, Escalated-dose somatostatin analogues for antiproliferative effect in GEPNETS: a systematic review. Endocrine 57(3), 366–375 (2017)
Article CAS PubMed Google Scholar
M. Pavel, D. O’Toole, F. Costa, J. Capdevila, D. Gross, R. Kianmanesh et al. ENETS consensus guidelines update for the management of distant metastatic disease of intestinal, pancreatic, bronchial neuroendocrine neoplasms (NEN) and NEN of unknown primary site. Neuroendocrinology 103(2), 172–185 (2016)
Article CAS PubMed Google Scholar
S. Singh, D. Granberg, E. Wolin, R. Warner, M. Sissons, T. Kolarova et al. Patient-reported burden of a neuroendocrine tumor (NET) diagnosis: results from the first global survey of patients with NETs. J. Glob. Oncol. 3(1), 43–53 (2017)
S. Das, T. Al-Toubah, G. El-Haddad, J. Strosberg, (177)Lu-DOTATATE for the treatment of gastroenteropancreatic neuroendocrine tumors. Expert. Rev. Gastroenterol. Hepatol. 13(11), 1023–1031 (2019)
Article CAS PubMed PubMed Central Google Scholar
E.S. Mittra, Neuroendocrine Tumor Therapy: (177)Lu-DOTATATE. AJR Am. J. Roentgenol. 211(2), 278–285 (2018)
A. Godara, N.S. Siddiqui, M.M. Byrne, M.W. Saif, The safety of lanreotide for neuroendocrine tumor. Expert. Opin. Drug. Saf. 18(1), 1–10 (2019)
Article CAS PubMed Google Scholar
E.B. Geer, J. Sisco, D.T. Adelman, W.H. Ludlam, A. Haviv, S. Liu et al. Patient reported outcome data from acromegaly patients treated with injectable somatostatin receptor ligands (SRLs) in routine clinical practice. BMC Endocr. Disord. 20(1), 117 (2020)
Article CAS PubMed PubMed Central Google Scholar
T. Ito, Y. Honma, S. Hijioka, A. Kudo, A. Fukutomi, A. Nozaki et al. Phase II study of lanreotide autogel in Japanese patients with unresectable or metastatic well-differentiated neuroendocrine tumors. Invest. N. Drugs 35(4), 499–508 (2017)
P. Burman, J. Besjakov, T. Svensjö, Large fat and skin necroses after deep subcutaneous injections of a slow-release somatostatin analogue in a woman with acromegaly. Growth Horm. IGF Res. 20(6), 438–440 (2010)
Article CAS PubMed Google Scholar
D. O’Toole, P.L. Kunz, S.M. Webb, G. Goldstein, S. Khawaja, M. McDonnell et al. PRESTO 2: an international survey to evaluate patients’ injection experiences with the latest devices/formulations of long-acting somatostatin analog therapies for neuroendocrine tumors or acromegaly. Adv. Ther. 40(2), 671–690 (2023)
D.T. Adelman, D. Van Genechten, C.M. Megret, X.T. Truong Thanh, P. Hand, W.A. Martin, Co-creation of a lanreotide autogel/depot syringe for the treatment of acromegaly and neuroendocrine tumours through collaborative human factor studies. Adv. Ther. 36(12), 3409–3423 (2019)
Article PubMed PubMed Central Google Scholar
S.E. Aapkes, R.J. de Haas, L.H.P. Bernts, C.J. Blijdorp, S.E.I. Dekker, M.D.A. van Gastel et al. Incident gallstones during somatostatin analog treatment are associated with acute biliary complications especially after discontinuation. Drugs R. D. 21(2), 179–188 (2021)
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