Friedman SL, Pinzani M (2022) Hepatic fibrosis 2022: unmet needs and a blueprint for the future. Hepatology 75:473–488
Arroyo V, Angeli P, Moreau R et al (2021) The systemic inflammation hypothesis: towards a new paradigm of acute decompensation and multiorgan failure in cirrhosis. J Hepatol 74:670–685
Wang Y, Wang J, Zhang J et al (2024) Stiffness sensing via Piezo1 enhances macrophage efferocytosis and promotes the resolution of liver fibrosis. Sci Adv 10:eadj3289
Kisseleva T, Brenner D (2021) Molecular and cellular mechanisms of liver fibrosis and its regression. Nat Rev Gastroenterol Hepatol 18:151–166
López Tórrez SM, Ayala CO, Ruggiro PB et al (2024) Accuracy of prognostic serological biomarkers in predicting liver fibrosis severity in people with metabolic dysfunction-associated steatotic liver disease: a meta-analysis of over 40,000 participants. Front Nutr 11:1284509
Im WH, Song JS, Jang W (2022) Noninvasive staging of liver fibrosis: review of current quantitative CT and MRI-based techniques. Abdom Radiol 47:3051–3067
Guglielmo FF, Barr RG, Yokoo T et al (2023) Liver fibrosis, fat, and iron evaluation with MRI and fibrosis and fat evaluation with US: a practical guide for radiologists. Radiographics 43:e220181
Li M, Yang H, Liu Y et al (2021) Comparison of the diagnostic performance of 2D and 3D MR elastography in staging liver fibrosis. Eur Radiol 31:9468–9478
Hu G, Zhang X, Liang W et al (2016) Assessment of liver fibrosis in rats by MRI with apparent diffusion coefficient and T1 relaxation time in the rotating frame. J Magn Reson Imaging 43:1082–1089
Huang H, Che-Nordin N, Wang LF et al (2019) High performance of intravoxel incoherent motion diffusion MRI in detecting viral hepatitis-b induced liver fibrosis. Ann Transl Med 7:39
Park JH, Seo N, Chung YE et al (2021) Noninvasive evaluation of liver fibrosis: comparison of the stretched exponential diffusion-weighted model to other diffusion-weighted MRI models and transient elastography. Eur Radiol 31:4813–4823
Venkatesh SK, Yin M, Takahashi N et al (2015) Non-invasive detection of liver fibrosis: MR imaging features vs. MR elastography. Abdom Imaging 40:766–775
Martin DR, Lauenstein T, Kalb B et al (2012) Liver MRI and histological correlates in chronic liver disease on multiphase gadolinium-enhanced 3D gradient echo imaging. J Magn Reson Imaging 36:422–429
Chundru S, Kalb B, Arif-Tiwari H et al (2014) MRI of diffuse liver disease: characteristics of acute and chronic diseases. Diagn Interv Radiol 20:200–208
Nakazawa Y, Okada M, Hyodo T et al (2024) Comparison between CT volumetry, technetium(99m) galactosyl-serum-albumin scintigraphy, and gadoxetic-acid-enhanced MRI to estimate the liver fibrosis stage in preoperative patients. Eur Radiol 34:2212–2222
Goshima S, Kanematsu M, Watanabe H et al (2012) Gd-EOB-DTPA-enhanced MR imaging: prediction of hepatic fibrosis stages using liver contrast enhancement index and liver-to-spleen volumetric ratio. J Magn Reson Imaging 36:1148–1153
Duan T, Jiang H, Xia C et al (2020) Assessing liver function in liver tumors patients: the performance of T1 mapping and residual liver volume on Gd-EOBDTPA-enhanced MRI. Front Med (Lausanne) 7:215
Zhou ZP, Long LL, Qiu WJ et al (2017) Comparison of 10- and 20-min hepatobiliary phase images on Gd-EOB-DTPA-enhanced MRI T1 mapping for liver function assessment in clinic. Abdom Radiol 42:2272–2278
Zou J, Jiang Y, Fan F et al (2024) The application of B1 inhomogeneity-corrected variable flip angle T1 mapping for assessing liver fibrosis. Magn Reson Imaging 113:110215
Yoon JH, Lee JM, Kim E, Okuaki T, Han JK (2017) Quantitative liver function analysis: volumetric T1 mapping with fast multisection B(1) inhomogeneity correction in hepatocyte-specific contrast-enhanced liver MR imaging. Radiology 282:408–417
Yamada A, Hara T, Li F et al (2011) Quantitative evaluation of liver function with use of gadoxetate disodium-enhanced MR imaging. Radiology 260:727–733
Dahlqvist Leinhard O, Dahlström N, Kihlberg J et al (2012) Quantifying differences in hepatic uptake of the liver specific contrast agents Gd-EOB-DTPA and Gd-BOPTA: a pilot study. Eur Radiol 22:642–653
Yoon JH, Lee JM, Kang HJ et al (2019) Quantitative assessment of liver function by using gadoxetic acid-enhanced MRI: hepatocyte uptake ratio. Radiology 290:125–133
Levitt DG (2003) The pharmacokinetics of the interstitial space in humans. BMC Clin Pharmacol 3:3
Desmet VJ, Gerber M, Hoofnagle JH, Manns M, Scheuer PJ (1994) Classification of chronic hepatitis: diagnosis, grading and staging. Hepatology 19:1513–1520
Zhang L, Long X, Chen L et al (2024) Detecting cellular microstructural changes of liver fibrosis with time-dependent diffusion MRI. Radiology 313:e240343
Parola M, Pinzani M (2019) Liver fibrosis: pathophysiology, pathogenetic targets and clinical issues. Mol Aspects Med 65:37–55
Ratziu V, Charlotte F, Heurtier A et al (2005) Sampling variability of liver biopsy in nonalcoholic fatty liver disease. Gastroenterology 128:1898–1906
Rosenberg WM, Voelker M, Thiel R et al (2004) Serum markers detect the presence of liver fibrosis: a cohort study. Gastroenterology 127:1704–1713
Boursier J, Vergniol J, Guillet A et al (2016) Diagnostic accuracy and prognostic significance of blood fibrosis tests and liver stiffness measurement by FibroScan in non-alcoholic fatty liver disease. J Hepatol 65:570–578
Hsu C, Caussy C, Imajo K et al (2019) Magnetic resonance vs transient elastography analysis of patients with nonalcoholic fatty liver disease: a systematic review and pooled analysis of individual participants. Clin Gastroenterol Hepatol 17:630–637.e8
Verloh N, Utpatel K, Haimerl M et al (2018) Detecting liver fibrosis with Gd-EOB-DTPA-enhanced MRI: a confirmatory study. Sci Rep 8:6207
Ueno A, Masugi Y, Yamazaki K et al (2014) OATP1B3 expression is strongly associated with Wnt/β-catenin signalling and represents the transporter of gadoxetic acid in hepatocellular carcinoma. J Hepatol 61:1080–1087
Ma Y, Zou C, Yang Y et al (2024) Arachidonic acid enhances hepatocyte bile acid uptake and alleviates cholestatic liver disease by upregulating OATP1 expression. Food Funct 15:9916–9927
Takayama Y, Nishie A, Ishimatsu K et al (2022) Diagnostic potential of T1ρ and T2 relaxations in assessing the severity of liver fibrosis and necro-inflammation. Magn Reson Imaging 87:104–112
Katsube T, Okada M, Kumano S et al (2011) Estimation of liver function using T1 mapping on Gd-EOB-DTPA-enhanced magnetic resonance imaging. Invest Radiol 46:277–283
Ding Y, Rao SX, Meng T et al (2014) Usefulness of T1 mapping on Gd-EOB-DTPA-enhanced MR imaging in assessment of non-alcoholic fatty liver disease. Eur Radiol 24:959–966
Feier D, Balassy C, Bastati N et al (2013) Liver fibrosis: histopathologic and biochemical influences on diagnostic efficacy of hepatobiliary contrast-enhanced MR imaging in staging. Radiology 269:460–468
Sheng RF, Wang HQ, Yang L et al (2017) Assessment of liver fibrosis using T1 mapping on Gd-EOB-DTPA-enhanced magnetic resonance. Dig Liver Dis 49:789–795
Bi XJ, Zhang XQ, Zhang T et al (2021) Quantitative assessment of liver function with hepatocyte fraction: comparison with T1 relaxation-based indices. Eur J Radiol 141:109779
Noda Y, Goshima S, Okuaki T et al (2020) Hepatocyte fraction: correlation with noninvasive liver functional biomarkers. Abdom Radiol 45:83–89
Comments (0)