King NY, Mesiano D, Ahmed I, et al. A common cause of hair loss? Clin Exp Dermatol. 2021;46(1):203–6.
Yin L, Svigos K, Gutierrez D, et al. Low-dose oral Minoxidil increases hair density and thickness in androgenetic alopecia: a retrospective analysis of 60 patients. J Eur Acad Dermatology Venereology: JEADV. 2022;36(3):e200–2.
Huang CH, Fu Y, Chi CC. Health-Related quality of life, depression, and Self-esteem in patients with androgenetic alopecia: A systematic review and Meta-analysis. JAMA Dermatology. 2021;157(8):963–70.
Prendke M, Kanti-Schmidt V, Wilborn D et al. Quality of life in children and adolescents with alopecia areata-A systematic review. Journal of the European Academy of Dermatology and Venereology: JEADV. 2023.
Minokawa Y, Sawada Y, Nakamura M. Lifestyle factors involved in the pathogenesis of alopecia areata. Int J Mol Sci. 2022;23(3):1038.
CAS PubMed PubMed Central Google Scholar
Chen L, Zhang J, Wang L, et al. The efficacy and safety of finasteride combined with topical Minoxidil for androgenetic alopecia: A systematic review and Meta-analysis. Aesthetic Plast Surg. 2020;44(3):962–70.
Varothai S, Bergfeld WF. Androgenetic alopecia: an evidence-based treatment update. Am J Clin Dermatolog. 2014;15(3):217–30.
Jimenez JJ, Wikramanayake TC, Bergfeld W, et al. Efficacy and safety of a low-level laser device in the treatment of male and female pattern hair loss: a multicenter, randomized, Sham device-controlled, double-blind study. Am J Clin Dermatol. 2014;15(2):115–27.
PubMed PubMed Central Google Scholar
Gubelin Harcha W, Barboza Martínez J, Tsai TF, et al. A randomized, active- and placebo-controlled study of the efficacy and safety of different doses of dutasteride versus placebo and finasteride in the treatment of male subjects with androgenetic alopecia. J Am Acad Dermatol. 2014;70(3):489–e4983.
Verma K, Tegta GR, Verma G, et al. A study to compare the efficacy of Platelet-rich plasma and Minoxidil therapy for the treatment of androgenetic alopecia. Int J Trichology. 2019;11(2):68–79.
CAS PubMed PubMed Central Google Scholar
Liu RH, Xu LJ, McCarty JC, et al. A scoping review on complications in modern hair transplantation: more than just splitting hairs. Aesthetic Plast Surg. 2025;49(3):585–95.
Vañó-Galván S, Pirmez R, Hermosa-Gelbard A, et al. Safety of low-dose oral Minoxidil for hair loss: A multicenter study of 1404 patients. J Am Acad Dermatol. 2021;84(6):1644–51.
Wang Y, Zhang H, Zheng Q, et al. Botulinum toxin as a double-edged sword in alopecia: A systematic review. J Cosmet Dermatol. 2020;19(10):2560–5.
Starace M, Alessandrini A, Brandi N, et al. Preliminary results of the use of scalp microneedling in different types of alopecia. J Cosmet Dermatol. 2020;19(3):646–50.
Hosking AM, Juhasz M, Atanaskova Mesinkovska N. Complementary and alternative treatments for alopecia: A comprehensive review. Skin Appendage Disorders. 2019;5(2):72–89.
Yassine S, Alaaeddine N. Mesenchymal stem cell exosomes and cancer: controversies and prospects. Adv Biology. 2022;6(2):e2101050.
Liu S, Wang W, Chen Z, et al. An osteoimmunomodulatory biopatch potentiates stem cell therapies for bone regeneration by simultaneously regulating IL-17/Ferroptosis signaling pathways. Volume 11. Baden-Wurttemberg, Germany: Advanced Science (Weinheim; 2024. p. e2401882. 35.
Zhao M, Kang M, Wang J, et al. Stem Cell-Derived nanovesicles embedded in Dual-Layered hydrogel for programmed ROS regulation and comprehensive tissue regeneration in burn wound healing. Adv Mater (Deerfield Beach Fla). 2024;36(32):e2401369.
Hofer HR, Tuan RS. Secreted trophic factors of mesenchymal stem cells support neurovascular and musculoskeletal therapies. Stem Cell Res Ther. 2016;7(1):131.
PubMed PubMed Central Google Scholar
Liu Q, Liu K, Cui G, et al. Lung regeneration by multipotent stem cells residing at the bronchioalveolar-duct junction. Nat Genet. 2019;51(4):728–38.
Fan H, Goodwin AJ, Chang E, et al. Endothelial progenitor cells and a stromal cell-derived factor-1α analogue synergistically improve survival in sepsis. Am J Respir Crit Care Med. 2014;189(12):1509–19.
CAS PubMed PubMed Central Google Scholar
Mao M, Wang SN, Lv XJ, et al. Intravenous delivery of bone marrow-derived endothelial progenitor cells improves survival and attenuates lipopolysaccharide-induced lung injury in rats. Shock (Augusta Ga). 2010;34(2):196–204.
Zhou Y, Li P, Goodwin AJ, et al. Exosomes from endothelial progenitor cells improve the outcome of a murine model of sepsis. Mol Ther. 2018;26(5):1375–84.
CAS PubMed PubMed Central Google Scholar
Zhou Y, Li P, Goodwin AJ, et al. Exosomes from endothelial progenitor cells improve outcomes of the lipopolysaccharide-induced acute lung injury. Crit Care (London England). 2019;23(1):44.
Yang SH, Park MJ, Yoon IH, et al. Soluble mediators from mesenchymal stem cells suppress T cell proliferation by inducing IL-10. Exp Mol Med. 2009;41(5):315–24.
CAS PubMed PubMed Central Google Scholar
Zaripova LN, Midgley A, Christmas SE, et al. Mesenchymal stem cells in the pathogenesis and therapy of autoimmune and autoinflammatory diseases. Int J Mol Sci. 2023;24(22):16040.
CAS PubMed PubMed Central Google Scholar
Chen H, Yamaguchi S, Wang Y, et al. Cytoprotective role of human dental pulp stem cell-conditioned medium in chemotherapy-induced alopecia. Stem Cell Res Ther. 2024;15(1):84.
CAS PubMed PubMed Central Google Scholar
Jeon SH, Kim H, Sung JH. Hypoxia enhances the hair growth-promoting effects of embryonic stem cell-derived mesenchymal stem cells via NADPH oxidase 4. Biomedicine & Pharmacotherapy = Biomedecine & Pharmacotherapie. 2023;159:114303.
Wu X, Huang X, Zhu Q, et al. Hybrid hair follicle stem cell extracellular vesicles co-delivering finasteride and gold nanoparticles for androgenetic alopecia treatment. J Controlled Release: Official J Controlled Release Soc. 2024;373:652–66.
Bellei B, Migliano E, Picardo M. Research update of adipose tissue-based therapies in regenerative dermatology. Stem Cell Reviews Rep. 2022;18(6):1956–73.
Watabe R, Yamaguchi T, Kabashima-Kubo R, et al. Leptin controls hair follicle cycling. Exp Dermatol. 2014;23(4):228–9.
Sung JH. Effective and economical cell therapy for hair regeneration. Biomedicine & Pharmacotherapy = Biomedecine & Pharmacotherapie; 2023;157:113988.
Won CH, Park GH, Wu X, et al. The basic mechanism of hair growth stimulation by Adipose-derived stem cells and their secretory factors. Curr Stem Cell Res Therapy. 2017;12(7):535–43.
Nilforoushzadeh MA, Aghdami N, Taghiabadi E. Effects of Adipose-Derived stem cells and Platelet-Rich plasma exosomes on the inductivity of hair dermal papilla cells. Cell J. 2021;23(5):576–83.
PubMed PubMed Central Google Scholar
González R, Moffatt G, Hagner A, et al. Platelet-derived growth factor signaling modulates adult hair follicle dermal stem cell maintenance and self-renewal. NPJ Regen Med. 2017;2:11.
PubMed PubMed Central Google Scholar
Lachgar S, Moukadiri H, Jonca F, et al. Vascular endothelial growth factor is an autocrine growth factor for hair dermal papilla cells. J Invest Dermatol. 1996;106(1):17–23.
Lin WH, Xiang LJ, Shi HX, et al. Fibroblast growth factors stimulate hair growth through β-catenin and Shh expression in C57BL/6 mice. Biomed Res Int. 2015;2015:730139.
PubMed PubMed Central Google Scholar
Lee SH, Yoon J, Shin SH, Zahoor M, Kim HJ, Park PJ, Park WS, Min do S, Kim HY, Choi KY. Valproic acid induces hair regeneration in murine model and activates alkaline phosphatase activity in human dermal papilla cells. PLoS ONE. 2012;7(4):e34152.
CAS PubMed PubMed Central Google Scholar
Tomita Y, Akiyama M, Shimizu H. PDGF isoforms induce and maintain anagen phase of murine hair follicles. J Dermatol Sci. 2006;43(2):105–15.
Nicu C, O’Sullivan JDB, Ramos R, et al. Dermal adipose tissue secretes HGF to promote human hair growth and pigmentation. J Invest Dermatol. 2021;141(7):1633–e164513.
Rajendran RL, Gangadaran P, Seo CH, et al. Macrophage-Derived Extracell Vesicle Promotes Hair Growth Cells. 2020;9(4):856.
Bak DH, Choi MJ, Kim SR, et al. Human umbilical cord blood mesenchymal stem cells engineered to overexpress growth factors accelerate outcomes in hair growth. Korean J Physiol Pharmacology: Official J Korean Physiological Soc Korean Soc Pharmacol. 2018;22(5):555–66.
Gentile P, Garcovich S. Advances in regenerative stem cell therapy in androgenic alopecia and hair loss: Wnt pathway, growth-Factor, and mesenchymal stem cell signaling impact analysis on cell growth and hair follicle development. Cells. 2019;8(5):466.
Comments (0)