Available online 3 October 2025, 101080

Ectopic varices are dilated non-gastroesophageal mesoportal veins that occur due to hepatic portal hypertension, portomesenteric occlusion, or prior abdominal surgeries, with less common causes including congenital conditions. These varices can occur in various locations, including the duodenum, jejunum, large bowel, and biliary system, and can lead to clinically significant gastrointestinal hemorrhages warranting intervention. An understanding of ectopic variceal anatomy and the etiology of variceal bleeding is imperative to optimal treatment. Despite a lack of standardized treatment guidelines, endovascular management remains vital for controlling bleeding and improving patient outcomes.

© 2025 The Author(s). Published by Elsevier Inc.