Author links open overlay panel, Section snippetsDear Editor,We read with great interest the study by Rhodes et al., which offers valuable preliminary evidence on bromocriptine as a dopaminergic adjunct for fever in acute neurologic injury [1]. The standardized dosing and exploratory subgroup analysis strengthen its clinical relevance, though several unaddressed design and translational issues warrant further consideration to clarify bromocriptine's role in practice.
The choice of Tmax over 24-h windows as the primary endpoint may obscure clinically
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Clinical trial registration details/numberNot applicable, as this study does not report a clinical trial.
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Human ethics and consent to participate declarationsNot applicable, as no patient data were collected or analyzed in this study.
Generative AI use statementPaperpal and ChatGPT 5, were utilized solely for language, grammar, and stylistic refinement. These tools had no role in the conceptualization, data analysis, interpretation of results, or substantive content development of this manuscript. All intellectual contributions, data analysis, and scientific interpretations remain the sole work of the authors. The final content was critically reviewed and edited to ensure accuracy and originality. The authors take full responsibility for the accuracy,
CRediT authorship contribution statementShyam Sundar Sah: Conceptualization, Methodology, Writing – original draft, Writing – review & editing. Abhishek Kumbhalwar: Project administration, Supervision, Validation, Writing – original draft, Writing – review & editing.
Declaration of competing interestNone.
References (5)M. Rhodes et al.Evaluation of bromocriptine for the reduction of fever in patients with acute neurologic injury: a retrospective cohort studyJ Crit Care
(2025)
M. Sund-Levander et al.Time for a change to assess and evaluate body temperature in clinical practiceInt J Nurs Pract
(2009)
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