analysis of variance

T cell receptor T3 zeta chain

central nervous system

differentially expressed genes

experimental autoimmune encephalomyelitis

fibronectin-related genes

Glyceraldehyde phosphate dehydrogenase

Gene Expression Omnibus

gene set enrichment analysis

genome-wide association study

Integrative Epidemiology Unit

immunoglobulin-like transcript

interferon regulatory factor-1

instrumental variables

inverse variance weighted

Kelch-like ECH-associated protein

Kyoto Encyclopedia of Genes and Genomes

leukocyte immunoglobulin-like receptor subfamily B

Mendelian randomization

natural cytotoxicity receptors

nuclear factor erythroid 2-related factor

natural killer group 2 member D

oligodendrocyte precursor cells

Principal component analysis

randomized controlled trials

ras homolog gene family member A

Rho associated coiled-coil containing protein kinase 1

reactive oxygen species

relapsing-remitting multiple sclerosis

reverse transcription-quantitative polymerase chain reaction

Single-cell RNA sequencing

systemic lupus erythematosus

single-nucleotide polymorphisms

signal transducer and activator of transcription 1

stromal interaction molecule

soluble TNF receptors

tumor necrosis factor-α

t-distributed stochastic neighbor embedding

vascular endothelial growth factor

zeta-chain-associated protein kinase