Eichenfield DZ, Sprague J, Eichenfield LF. Management of acne vulgaris: a review. JAMA. 2021;326:2055–67.
Kwon HH, Yoon HS, Suh DH, et al. A nationwide study of acne treatment patterns in Korea: analysis of patient preconceived notions and dermatologist suggestion for treatment. Acta Derm Venereol. 2012;92:236–40.
Tan JK, Bhate K. A global perspective on the epidemiology of acne. Br J Dermatol. 2015;172(Suppl 1):3–12.
Dreno B, Layton A, Bettoli V, et al. Evaluation of the prevalence, risk factors, clinical characteristics, and burden of acne scars among active acne patients in Brazil, France, and the USA. J Am Acad Dermatol. 2017;76:ab132.
Tan J, Beissert S, Cook-Bolden F, et al. Evaluation of psychological well-being and social impact of atrophic acne scarring: a multinational, mixed-methods study. JAAD Int. 2022;6:43–50.
Tunca M, Balik ZB, Uncu HB, Botsali A. Stigmatization and psychosocial burden in acne patients. J Cosmet Dermatol. 2025;24:e16678.
Yoon JY, Kwon HH, Min SU, et al. Epigallocatechin-3-gallate improves acne in humans by modulating intracellular molecular targets and inhibiting P. acnes. J Invest Dermatol. 2013;133:429–40.
Article CAS PubMed Google Scholar
Jennings T, Duffy R, McLarney M, et al. Acne scarring-pathophysiology, diagnosis, prevention and education: Part I. J Am Acad Dermatol. 2024;90:1123–34.
Norris JF, Cunliffe WJ. A histological and immunocytochemical study of early acne lesions. Br J Dermatol. 1988;118:651–9.
Article CAS PubMed Google Scholar
Suh DH, Kwon HH. What’s new in the physiopathology of acne? Br J Dermatol. 2015;172(Suppl 1):13–9.
Article CAS PubMed Google Scholar
Carlavan I, Bertino B, Rivier M, et al. Atrophic scar formation in patients with acne involves long-acting immune responses with plasma cells and alteration of sebaceous glands. Br J Dermatol. 2018;179:906–17.
Article CAS PubMed Google Scholar
Connolly D, Vu HL, Mariwalla K, et al. Acne scarring-pathogenesis, evaluation, and treatment options. J Clin Aesthet Dermatol. 2017;10:12–23.
PubMed PubMed Central Google Scholar
Fabbrocini G, Annunziata MC, D’Arco V, et al. Acne scars: pathogenesis, classification and treatment. Dermatol Res Pract. 2010;2010:893080.
Article PubMed PubMed Central Google Scholar
Moon J, Yoon JY, Yang JH, et al. Atrophic acne scar: a process from altered metabolism of elastic fibres and collagen fibres based on transforming growth factor-beta1 signalling. Br J Dermatol. 2019;181:1226–37.
Article CAS PubMed Google Scholar
Hession MT, Graber EM. Atrophic acne scarring: a review of treatment options. J Clin Aesthet Dermatol. 2015;8:50–8.
PubMed PubMed Central Google Scholar
Lee JH, Yoon JY, Kim DH, et al. Potential of cannabidiol as acne and acne scar treatment: novel insights into molecular pathways of pathophysiological factors. Arch Dermatol Res. 2024. https://doi.org/10.1007/s00403-024-03131-9.
Article PubMed PubMed Central Google Scholar
Qoreishi SH, Gholizadeh N, Rokni GR, et al. Advancements in acne scar treatment: exploring novel therapies. J Cosmet Dermatol. 2025;24:e70183.
Article PubMed PubMed Central Google Scholar
Renzi M, Mclarney M, Jennings T, et al. Procedural and surgical treatment modalities for acne scarring: Part II. J Am Acad Dermatol. 2024;90:1137–50.
van Zuuren EJ, Arents BWM, Vermeulen S, et al. Harmonizing measurement of satisfaction with acne scar treatments: can we all sing the same tune? Dermatol Surg. 2021;47:1323–4.
Article PubMed PubMed Central Google Scholar
Kurokawa I, Oiso N, Kawada A. Adjuvant alternative treatment with chemical peeling and subsequent iontophoresis for postinflammatory hyperpigmentation, erosion with inflamed red papules and non-inflamed atrophic scars in acne vulgaris. J Dermatol. 2017;44:401–5.
Article CAS PubMed Google Scholar
Kurokawa I, Yoshioka M, Ito S. Split-face comparative clinical trial using glyceryl-octyl-ascorbic acid/ascorbyl 2-phosphate 6-palmitate/DL-α-tocopherol phosphate complex treatment for postinflammatory hyperpigmentation, postinflammatory erythema and atrophic scar in acne vulgaris. J Dermatol. 2019;46:e347–8.
Kurokawa I. Non-surgical treatment with basic fibroblast growth factor for atrophic scars in acne vulgaris. J Dermatol. 2018;45:e238–9.
Miao L, Ma Y, Liu Z, et al. Modern techniques in addressing facial acne scars: a thorough analysis. Skin Res Technol. 2024;30:e13573.
Article PubMed PubMed Central Google Scholar
Tam C, Khong J, Tam K, et al. A comprehensive review of non-energy-based treatments for atrophic acne scarring. Clin Cosmet Investig Dermatol. 2022;15:455–69.
Article CAS PubMed PubMed Central Google Scholar
Goncharov EN, Koval OA, Igorevich EI, et al. Analyzing the clinical potential of stromal vascular fraction: a comprehensive literature review. Medicina Kaunas. 2024;60:221.
Article PubMed PubMed Central Google Scholar
Bora P, Majumdar AS. Adipose tissue-derived stromal vascular fraction in regenerative medicine: a brief review on biology and translation. Stem Cell Res Ther. 2017;8:145.
Article PubMed PubMed Central Google Scholar
Bowles AC, Wise RM, Gerstein BY, et al. Immunomodulatory effects of adipose stromal vascular fraction cells promote alternative activation macrophages to repair tissue damage. Stem Cells. 2017;35:2198–207.
Article CAS PubMed Google Scholar
Gentile P, De Angelis B, Pasin M, et al. Adipose-derived stromal vascular fraction cells and platelet-rich plasma: basic and clinical evaluation for cell-based therapies in patients with scars on the face. J Craniofac Surg. 2014;25:267–72.
Mbiine R, Wayengera M, Kiwanuka N, et al. Autologous adipose-derived stromal vascular fraction (SVF) in scar treatment among patients with keloids and hypertrophic scars: a systematic review and meta-analysis of current practices and outcomes. Am J Stem Cells. 2023;12:98–111.
PubMed PubMed Central Google Scholar
Behrangi E, Moradi S, Ghassemi M, et al. The investigation of the efficacy and safety of stromal vascular fraction in the treatment of nanofat-treated acne scar: a randomized blinded controlled clinical trial. Stem Cell Res Ther. 2022;13:298.
Article CAS PubMed PubMed Central Google Scholar
Roohaninasab M, Khodadad F, Sadeghzadeh-Bazargan A, et al. Efficacy of fractional CO(2) laser in combination with stromal vascular fraction (SVF) compared with fractional CO(2) laser alone in the treatment of burn scars: a randomized controlled clinical trial. Stem Cell Res Ther. 2023;14:269.
Article CAS PubMed PubMed Central Google Scholar
Roohaninasab M, Seifadini A, Atefi N, et al. Evaluating the effectiveness of stromal-vascular fraction (SVF) cells along with subcision method in the treatment of acne scars: a double-blind randomized controlled clinical trial study. J Cosmet Dermatol. 2022;21:6928–38.
Dreno B, Khammari A, Orain N, et al. ECCA grading scale: an original validated acne scar grading scale for clinical practice in dermatology. Dermatology. 2007;214:46–51.
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