Ackerman D, Simon MC (2014) Hypoxia, lipids, and cancer: surviving the harsh tumor microenvironment. Trends Cell Biol 24:472–478
PubMed PubMed Central CAS Google Scholar
Agarwala PK, Nie S, Reid GE, Kapoor S (2023) Global lipid remodelling by hypoxia aggravates migratory potential in pancreatic cancer while maintaining plasma membrane homeostasis. Biochimica Et Biophysica Acta (BBA) 1868:159398
Bangasser BL, Shamsan GA, Chan CE, Opoku KN, Tuzel E, Schlichtmann BW, Kasim JA, Fuller BJ, McCullough BR, Rosenfeld SS, Odde DJ (2017) Shifting the optimal stiffness for cell migration. Nat Commun 8:15313
PubMed PubMed Central CAS Google Scholar
Batta G, Soltesz L, Kovacs T, Bozo T, Meszar Z, Kellermayer M, Szollosi J, Nagy P (2018) Alterations in the properties of the cell membrane due to glycosphingolipid accumulation in a model of Gaucher disease. Sci Rep 8:157
PubMed PubMed Central Google Scholar
Brandi J, Dando I, Pozza ED, Biondani G, Jenkins R, Elliott V, Park K, Fanelli G, Zolla L, Costello E, Scarpa A, Cecconi D, Palmieri M (2017) Proteomic analysis of pancreatic cancer stem cells: functional role of fatty acid synthesis and mevalonate pathways. J Proteomics 150:310–322
Broadfield LA, Pane AA, Talebi A, Swinnen JV, Fendt SM (2021) Lipid metabolism in cancer: new perspectives and emerging mechanisms. Dev Cell 56:1363–1393
Butler LM, Perone Y, Dehairs J, Lupien LE, de Laat V, Talebi A, Loda M, Kinlaw WB, Swinnen JV (2020) Lipids and cancer: emerging roles in pathogenesis, diagnosis and therapeutic intervention. Adv Drug Deliv Rev 159:245–293
PubMed PubMed Central CAS Google Scholar
Camarda R, Zhou AY, Kohnz RA, Balakrishnan S, Mahieu C, Anderton B, Eyob H, Kajimura S, Tward A, Krings G, Nomura DK, Goga A (2016) Inhibition of fatty acid oxidation as a therapy for MYC-overexpressing triple-negative breast cancer. Nat Med 22:427–432
PubMed PubMed Central CAS Google Scholar
Cohen AE, Shi Z (2020) Do cell membranes flow like honey or jiggle like jello? BioEssays 42:e1900142
Colom A, Derivery E, Soleimanpour S, Tomba C, Molin MD, Sakai N, Gonzalez-Gaitan M, Matile S, Roux A (2018) A fluorescent membrane tension probe. Nat Chem 10:1118–1125
PubMed Central CAS Google Scholar
Cotte AK, Aires V, Fredon M, Limagne E, Derangere V, Thibaudin M, Humblin E, Scagliarini A, de Barros JP, Hillon P, Ghiringhelli F, Delmas D (2018) Lysophosphatidylcholine acyltransferase 2-mediated lipid droplet production supports colorectal cancer chemoresistance. Nat Commun 9:322
PubMed PubMed Central Google Scholar
Cross SE, Jin YS, Rao J, Gimzewski JK (2007) Nanomechanical analysis of cells from cancer patients. Nat Nanotechnol 2:780–783
Dobrzyn A, Ntambi JM (2005) The role of stearoyl-CoA desaturase in the control of metabolism. Prostaglandins Leukot Essent Fatty Acids 73:35–41
Dutta A, Mukku RP, Kumar GA, Jafurulla M, Raghunand TR, Chattopadhyay A (2022) Integrity of the actin cytoskeleton of host macrophages is necessary for mycobacterial entry. J Membr Biol 255:623–632
PubMed PubMed Central CAS Google Scholar
Gavara N, Chadwick RS (2016) Relationship between cell stiffness and stress fiber amount, assessed by simultaneous atomic force microscopy and live-cell fluorescence imaging. Biomech Model Mechanobiol 15:511–523
Gensbittel V, Krater M, Harlepp S, Busnelli I, Guck J, Goetz JG (2021) Mechanical adaptability of tumor cells in metastasis. Dev Cell 56:164–179
Gunther G, Malacrida L, Jameson DM, Gratton E, Sanchez SA (2021) Laurdan since Weber: the quest for visualizing membrane heterogeneity. Acc Chem Res 54:976–987
PubMed PubMed Central CAS Google Scholar
Gupta A, Kallianpur M, Roy DS, Engberg O, Chakrabarty H, Huster D, Maiti S (2023) Different membrane order measurement techniques are not mutually consistent. Biophys J 122:964–972
Han YL, Pegoraro AF, Li H, Li K, Yuan Y, Xu G, Gu Z, Sun J, Hao Y, Gupta SK, Li Y, Tang W, Tang X, Teng L, Fredberg JJ, Guo M (2020) Cell swelling, softening and invasion in a three-dimensional breast cancer model. Nat Phys 16:101–108
Janmey PA, McCulloch CA (2007) Cell mechanics: integrating cell responses to mechanical stimuli. Annu Rev Biomed Eng 9:1–34
Kabarowski JH (2009) G2A and LPC: regulatory functions in immunity. Prostaglandins Other Lipid Mediat 89:73–81
PubMed PubMed Central CAS Google Scholar
Kaiser RD, London E (1998) Location of diphenylhexatriene (DPH) and its derivatives within membranes: comparison of different fluorescence quenching analyses of membrane depth. Biochemistry 37:8180–8190
Lee JS, Oh SJ, Choi HJ, Kang JH, Lee SH, Ha JS, Woo SM, Jang H, Lee H, Kim SY (2020) ATP production relies on fatty acid oxidation rather than glycolysis in pancreatic ductal adenocarcinoma. Cancers (Basel). https://doi.org/10.3390/cancers12092477
Article PubMed PubMed Central Google Scholar
Mashima T, Seimiya H, Tsuruo T (2009) De novo fatty-acid synthesis and related pathways as molecular targets for cancer therapy. Br J Cancer 100:1369–1372
PubMed PubMed Central CAS Google Scholar
Migita T, Ruiz S, Fornari A, Fiorentino M, Priolo C, Zadra G, Inazuka F, Grisanzio C, Palescandolo E, Shin E, Fiore C, Xie W, Kung AL, Febbo PG, Subramanian A, Mucci L, Ma J, Signoretti S, Stampfer M, Hahn WC, Finn S, Loda M (2009) Fatty acid synthase: a metabolic enzyme and candidate oncogene in prostate cancer. J Natl Cancer Inst 101:519–532
PubMed PubMed Central CAS Google Scholar
Nimmakayala, R. K., Leon, F., Rachagani, S., Rauth, S., Nallasamy, P., Marimuthu, S., Shailendra, G. K., Chhonker, Y. S., Chugh, S., Chirravuri, R., Gupta, R., Mallya, K., Prajapati, D. R., Lele, S. M., T, C. C., J, L. G., Grandgenett, P. M., Hollingsworth, M. A., Murry, D. J., Batra, S. K., and Ponnusamy, M. P. (2021) Metabolic programming of distinct cancer stem cells promotes metastasis of pancreatic ductal adenocarcinoma. Oncogene 40, 215–231
Nowak SA, Chou T (2010) Models of dynamic extraction of lipid tethers from cell membranes. Phys Biol 7:026002
Padanad MS, Konstantinidou G, Venkateswaran N, Melegari M, Rindhe S, Mitsche M, Yang C, Batten K, Huffman KE, Liu J, Tang X, Rodriguez-Canales J, Kalhor N, Shay JW, Minna JD, McDonald J, Wistuba II, DeBerardinis RJ, Scaglioni PP (2016) Fatty acid oxidation mediated by Acyl-CoA synthetase long chain 3 is required for mutant KRAS lung tumorigenesis. Cell Rep 16:1614–1628
PubMed PubMed Central CAS Google Scholar
Parasassi T, De Stasio G, Ravagnan G, Rusch RM, Gratton E (1991) Quantitation of lipid phases in phospholipid vesicles by the generalized polarization of Laurdan fluorescence. Biophys J 60:179–189
PubMed PubMed Central CAS Google Scholar
Pontes B, Monzo P, Gauthier NC (2017) Membrane tension: a challenging but universal physical parameter in cell biology. Semin Cell Dev Biol 71:30–41
Raucher D, Sheetz MP (1999) Characteristics of a membrane reservoir buffering membrane tension. Biophys J 77:1992–2002
PubMed PubMed Central CAS Google Scholar
Romero-Garcia S, Lopez-Gonzalez JS, Baez-Viveros JL, Aguilar-Cazares D, Prado-Garcia H (2011) Tumor cell metabolism: an integral view. Cancer Biol Ther 12:939–948
PubMed PubMed Central CAS Google Scholar
Roy S, Kumar GA, Jafurulla M, Mandal C, Chattopadhyay A (2014) Integrity of the actin cytoskeleton of host macrophages is essential for Leishmania donovani infection. Biochim Biophys Acta 1838:2011–2018
Sezgin E, Kaiser HJ, Baumgart T, Schwille P, Simons K, Levental I (2012) Elucidating membrane structure and protein behavior using giant plasma membrane vesicles. Nat Protoc 7:1042–1051
Shimano H, Sato R (2017) SREBP-regulated lipid metabolism: convergent physiology - divergent pathophysiology. Nat Rev Endocrinol 13:710–730
Siegel RL, Miller KD, Jemal A (2020) Cancer statistics, 2020. CA Cancer J Clin 70:7–30
Sitarska E, Diz-
Comments (0)