Research ArticleInflammationNephrology Open Access | 10.1172/jci.insight.189825

Min Zhang,1,2 Bin Wang,1,2 Ding Sun,1 Xizhao Chen,2 Yena Zhou,2 Jin Yao,2 Liwen Du,3 Zehao Zhang,1 Hao Li,1 Zeyu Qu,1 Lu Chen,2 Qing Luo,1 Jie Zhang,1 Xinye Jin,1 Xiaowei Cheng,1 Jingxue Niu,1 Qinrui Xing,4 Xuezeng Tan,5 Tao Wang,6 Jie Liu,5 Lei Li,7,8,9 Qing Song,5,9 Xiangmei Chen,2 and Yizhi Chen1,2,10,11,12

1Department of Nephrology, Hainan Hospital of Chinese PLA General Hospital, Hainan Province Chen Xiangmei Academician Team Innovation Center for Kidney Diseases Research, Sanya, China.

2Senior Department of Nephrology, Chinese PLA General Hospital, State Key Laboratory of Kidney Diseases, National Clinical Research Center for Kidney Diseases, Beijing, China.

3Department of Emergency, Ningbo No. 2 Hospital, Ningbo, China.

4Department of Cardiology, Hainan Hospital of Chinese PLA General Hospital, Sanya, China.

5Department of Critical Care Medicine, and

6Department of Emergency, Hainan Hospital of Chinese PLA General Hospital, Sanya, China.

7Department of Emergency, Changhai Hospital, Naval Medical University, Shanghai, China.

8Department of Emergency, The Second Naval Hospital of Southern Theater Command of PLA, Sanya, China.

9Heatstroke Treatment and Research Center of PLA, Sanya, China.

10The Second School of Clinical Medicine, Southern Medical University, Guangzhou, China.

11Hainan Medical University, Haikou, China.

12Sanya Nephrology Medical Quality Control Center, Sanya, China.

Address correspondence to: Yizhi Chen, Department of Nephrology, Hainan Hospital of Chinese PLA General Hospital, Sanya, China. Email: yizchen@126.com. Or to: Xiangmei Chen, Senior Department of Nephrology, Chinese PLA General Hospital, Beijing, China. Email: xmchen301@126.com. Or to: Qing Song, Department of Critical Care Medicine, Hainan Hospital of Chinese PLA General Hospital, Sanya, China. Email: songqing3010301@sina.com.

Authorship note: MZ, BW, and DS contributed equally to this work.

Find articles by Zhang, M. in: PubMed | Google Scholar |

1Department of Nephrology, Hainan Hospital of Chinese PLA General Hospital, Hainan Province Chen Xiangmei Academician Team Innovation Center for Kidney Diseases Research, Sanya, China.

2Senior Department of Nephrology, Chinese PLA General Hospital, State Key Laboratory of Kidney Diseases, National Clinical Research Center for Kidney Diseases, Beijing, China.

3Department of Emergency, Ningbo No. 2 Hospital, Ningbo, China.

4Department of Cardiology, Hainan Hospital of Chinese PLA General Hospital, Sanya, China.

5Department of Critical Care Medicine, and

6Department of Emergency, Hainan Hospital of Chinese PLA General Hospital, Sanya, China.

7Department of Emergency, Changhai Hospital, Naval Medical University, Shanghai, China.

8Department of Emergency, The Second Naval Hospital of Southern Theater Command of PLA, Sanya, China.

9Heatstroke Treatment and Research Center of PLA, Sanya, China.

10The Second School of Clinical Medicine, Southern Medical University, Guangzhou, China.

11Hainan Medical University, Haikou, China.

12Sanya Nephrology Medical Quality Control Center, Sanya, China.

Address correspondence to: Yizhi Chen, Department of Nephrology, Hainan Hospital of Chinese PLA General Hospital, Sanya, China. Email: yizchen@126.com. Or to: Xiangmei Chen, Senior Department of Nephrology, Chinese PLA General Hospital, Beijing, China. Email: xmchen301@126.com. Or to: Qing Song, Department of Critical Care Medicine, Hainan Hospital of Chinese PLA General Hospital, Sanya, China. Email: songqing3010301@sina.com.

Authorship note: MZ, BW, and DS contributed equally to this work.

Find articles by Wang, B. in: PubMed | Google Scholar

1Department of Nephrology, Hainan Hospital of Chinese PLA General Hospital, Hainan Province Chen Xiangmei Academician Team Innovation Center for Kidney Diseases Research, Sanya, China.

2Senior Department of Nephrology, Chinese PLA General Hospital, State Key Laboratory of Kidney Diseases, National Clinical Research Center for Kidney Diseases, Beijing, China.

3Department of Emergency, Ningbo No. 2 Hospital, Ningbo, China.

4Department of Cardiology, Hainan Hospital of Chinese PLA General Hospital, Sanya, China.

5Department of Critical Care Medicine, and

6Department of Emergency, Hainan Hospital of Chinese PLA General Hospital, Sanya, China.

7Department of Emergency, Changhai Hospital, Naval Medical University, Shanghai, China.

8Department of Emergency, The Second Naval Hospital of Southern Theater Command of PLA, Sanya, China.

9Heatstroke Treatment and Research Center of PLA, Sanya, China.

10The Second School of Clinical Medicine, Southern Medical University, Guangzhou, China.

11Hainan Medical University, Haikou, China.

12Sanya Nephrology Medical Quality Control Center, Sanya, China.

Address correspondence to: Yizhi Chen, Department of Nephrology, Hainan Hospital of Chinese PLA General Hospital, Sanya, China. Email: yizchen@126.com. Or to: Xiangmei Chen, Senior Department of Nephrology, Chinese PLA General Hospital, Beijing, China. Email: xmchen301@126.com. Or to: Qing Song, Department of Critical Care Medicine, Hainan Hospital of Chinese PLA General Hospital, Sanya, China. Email: songqing3010301@sina.com.

Authorship note: MZ, BW, and DS contributed equally to this work.

Find articles by Sun, D. in: PubMed | Google Scholar

1Department of Nephrology, Hainan Hospital of Chinese PLA General Hospital, Hainan Province Chen Xiangmei Academician Team Innovation Center for Kidney Diseases Research, Sanya, China.

2Senior Department of Nephrology, Chinese PLA General Hospital, State Key Laboratory of Kidney Diseases, National Clinical Research Center for Kidney Diseases, Beijing, China.

3Department of Emergency, Ningbo No. 2 Hospital, Ningbo, China.

4Department of Cardiology, Hainan Hospital of Chinese PLA General Hospital, Sanya, China.

5Department of Critical Care Medicine, and

6Department of Emergency, Hainan Hospital of Chinese PLA General Hospital, Sanya, China.

7Department of Emergency, Changhai Hospital, Naval Medical University, Shanghai, China.

8Department of Emergency, The Second Naval Hospital of Southern Theater Command of PLA, Sanya, China.

9Heatstroke Treatment and Research Center of PLA, Sanya, China.

10The Second School of Clinical Medicine, Southern Medical University, Guangzhou, China.

11Hainan Medical University, Haikou, China.

12Sanya Nephrology Medical Quality Control Center, Sanya, China.

Address correspondence to: Yizhi Chen, Department of Nephrology, Hainan Hospital of Chinese PLA General Hospital, Sanya, China. Email: yizchen@126.com. Or to: Xiangmei Chen, Senior Department of Nephrology, Chinese PLA General Hospital, Beijing, China. Email: xmchen301@126.com. Or to: Qing Song, Department of Critical Care Medicine, Hainan Hospital of Chinese PLA General Hospital, Sanya, China. Email: songqing3010301@sina.com.

Authorship note: MZ, BW, and DS contributed equally to this work.

Find articles by Chen, X. in: PubMed | Google Scholar

1Department of Nephrology, Hainan Hospital of Chinese PLA General Hospital, Hainan Province Chen Xiangmei Academician Team Innovation Center for Kidney Diseases Research, Sanya, China.

2Senior Department of Nephrology, Chinese PLA General Hospital, State Key Laboratory of Kidney Diseases, National Clinical Research Center for Kidney Diseases, Beijing, China.

3Department of Emergency, Ningbo No. 2 Hospital, Ningbo, China.

4Department of Cardiology, Hainan Hospital of Chinese PLA General Hospital, Sanya, China.

5Department of Critical Care Medicine, and

6Department of Emergency, Hainan Hospital of Chinese PLA General Hospital, Sanya, China.

7Department of Emergency, Changhai Hospital, Naval Medical University, Shanghai, China.

8Department of Emergency, The Second Naval Hospital of Southern Theater Command of PLA, Sanya, China.

9Heatstroke Treatment and Research Center of PLA, Sanya, China.

10The Second School of Clinical Medicine, Southern Medical University, Guangzhou, China.

11Hainan Medical University, Haikou, China.

12Sanya Nephrology Medical Quality Control Center, Sanya, China.

Address correspondence to: Yizhi Chen, Department of Nephrology, Hainan Hospital of Chinese PLA General Hospital, Sanya, China. Email: yizchen@126.com. Or to: Xiangmei Chen, Senior Department of Nephrology, Chinese PLA General Hospital, Beijing, China. Email: xmchen301@126.com. Or to: Qing Song, Department of Critical Care Medicine, Hainan Hospital of Chinese PLA General Hospital, Sanya, China. Email: songqing3010301@sina.com.

Authorship note: MZ, BW, and DS contributed equally to this work.

Find articles by Zhou, Y. in: PubMed | Google Scholar

1Department of Nephrology, Hainan Hospital of Chinese PLA General Hospital, Hainan Province Chen Xiangmei Academician Team Innovation Center for Kidney Diseases Research, Sanya, China.

2Senior Department of Nephrology, Chinese PLA General Hospital, State Key Laboratory of Kidney Diseases, National Clinical Research Center for Kidney Diseases, Beijing, China.

3Department of Emergency, Ningbo No. 2 Hospital, Ningbo, China.

4Department of Cardiology, Hainan Hospital of Chinese PLA General Hospital, Sanya, China.

5Department of Critical Care Medicine, and

6Department of Emergency, Hainan Hospital of Chinese PLA General Hospital, Sanya, China.

7Department of Emergency, Changhai Hospital, Naval Medical University, Shanghai, China.

8Department of Emergency, The Second Naval Hospital of Southern Theater Command of PLA, Sanya, China.

9Heatstroke Treatment and Research Center of PLA, Sanya, China.

10The Second School of Clinical Medicine, Southern Medical University, Guangzhou, China.

11Hainan Medical University, Haikou, China.

12Sanya Nephrology Medical Quality Control Center, Sanya, China.

Address correspondence to: Yizhi Chen, Department of Nephrology, Hainan Hospital of Chinese PLA General Hospital, Sanya, China. Email: yizchen@126.com. Or to: Xiangmei Chen, Senior Department of Nephrology, Chinese PLA General Hospital, Beijing, China. Email: xmchen301@126.com. Or to: Qing Song, Department of Critical Care Medicine, Hainan Hospital of Chinese PLA General Hospital, Sanya, China. Email: songqing3010301@sina.com.

Authorship note: MZ, BW, and DS contributed equally to this work.

Find articles by Yao, J. in: PubMed | Google Scholar

1Department of Nephrology, Hainan Hospital of Chinese PLA General Hospital, Hainan Province Chen Xiangmei Academician Team Innovation Center for Kidney Diseases Research, Sanya, China.

2Senior Department of Nephrology, Chinese PLA General Hospital, State Key Laboratory of Kidney Diseases, National Clinical Research Center for Kidney Diseases, Beijing, China.

3Department of Emergency, Ningbo No. 2 Hospital, Ningbo, China.

4Department of Cardiology, Hainan Hospital of Chinese PLA General Hospital, Sanya, China.

5Department of Critical Care Medicine, and

6Department of Emergency, Hainan Hospital of Chinese PLA General Hospital, Sanya, China.

7Department of Emergency, Changhai Hospital, Naval Medical University, Shanghai, China.

8Department of Emergency, The Second Naval Hospital of Southern Theater Command of PLA, Sanya, China.

9Heatstroke Treatment and Research Center of PLA, Sanya, China.

10The Second School of Clinical Medicine, Southern Medical University, Guangzhou, China.

11Hainan Medical University, Haikou, China.

12Sanya Nephrology Medical Quality Control Center, Sanya, China.

Address correspondence to: Yizhi Chen, Department of Nephrology, Hainan Hospital of Chinese PLA General Hospital, Sanya, China. Email: yizchen@126.com. Or to: Xiangmei Chen, Senior Department of Nephrology, Chinese PLA General Hospital, Beijing, China. Email: xmchen301@126.com. Or to: Qing Song, Department of Critical Care Medicine, Hainan Hospital of Chinese PLA General Hospital, Sanya, China. Email: songqing3010301@sina.com.

Authorship note: MZ, BW, and DS contributed equally to this work.

Find articles by Du, L. in: PubMed | Google Scholar

1Department of Nephrology, Hainan Hospital of Chinese PLA General Hospital, Hainan Province Chen Xiangmei Academician Team Innovation Center for Kidney Diseases Research, Sanya, China.

2Senior Department of Nephrology, Chinese PLA General Hospital, State Key Laboratory of Kidney Diseases, National Clinical Research Center for Kidney Diseases, Beijing, China.

3Department of Emergency, Ningbo No. 2 Hospital, Ningbo, China.

4Department of Cardiology, Hainan Hospital of Chinese PLA General Hospital, Sanya, China.

5Department of Critical Care Medicine, and

6Department of Emergency, Hainan Hospital of Chinese PLA General Hospital, Sanya, China.

7Department of Emergency, Changhai Hospital, Naval Medical University, Shanghai, China.

8Department of Emergency, The Second Naval Hospital of Southern Theater Command of PLA, Sanya, China.

9Heatstroke Treatment and Research Center of PLA, Sanya, China.

10The Second School of Clinical Medicine, Southern Medical University, Guangzhou, China.

11Hainan Medical University, Haikou, China.

12Sanya Nephrology Medical Quality Control Center, Sanya, China.

Address correspondence to: Yizhi Chen, Department of Nephrology, Hainan Hospital of Chinese PLA General Hospital, Sanya, China. Email: yizchen@126.com. Or to: Xiangmei Chen, Senior Department of Nephrology, Chinese PLA General Hospital, Beijing, China. Email: xmchen301@126.com. Or to: Qing Song, Department of Critical Care Medicine, Hainan Hospital of Chinese PLA General Hospital, Sanya, China. Email: songqing3010301@sina.com.

Authorship note: MZ, BW, and DS contributed equally to this work.

Find articles by Zhang, Z. in: PubMed | Google Scholar

1Department of Nephrology, Hainan Hospital of Chinese PLA General Hospital, Hainan Province Chen Xiangmei Academician Team Innovation Center for Kidney Diseases Research, Sanya, China.

2Senior Department of Nephrology, Chinese PLA General Hospital, State Key Laboratory of Kidney Diseases, National Clinical Research Center for Kidney Diseases, Beijing, China.

3Department of Emergency, Ningbo No. 2 Hospital, Ningbo, China.

4Department of Cardiology, Hainan Hospital of Chinese PLA General Hospital, Sanya, China.

5Department of Critical Care Medicine, and

6Department of Emergency, Hainan Hospital of Chinese PLA General Hospital, Sanya, China.

7Department of Emergency, Changhai Hospital, Naval Medical University, Shanghai, China.

8Department of Emergency, The Second Naval Hospital of Southern Theater Command of PLA, Sanya, China.

9Heatstroke Treatment and Research Center of PLA, Sanya, China.

10The Second School of Clinical Medicine, Southern Medical University, Guangzhou, China.

11Hainan Medical University, Haikou, China.

12Sanya Nephrology Medical Quality Control Center, Sanya, China.

Address correspondence to: Yizhi Chen, Department of Nephrology, Hainan Hospital of Chinese PLA General Hospital, Sanya, China. Email: yizchen@126.com. Or to: Xiangmei Chen, Senior Department of Nephrology, Chinese PLA General Hospital, Beijing, China. Email: xmchen301@126.com. Or to: Qing Song, Department of Critical Care Medicine, Hainan Hospital of Chinese PLA General Hospital, Sanya, China. Email: songqing3010301@sina.com.

Authorship note: MZ, BW, and DS contributed equally to this work.

Find articles by Li, H. in: PubMed | Google Scholar

1Department of Nephrology, Hainan Hospital of Chinese PLA General Hospital, Hainan Province Chen Xiangmei Academician Team Innovation Center for Kidney Diseases Research, Sanya, China.

2Senior Department of Nephrology, Chinese PLA General Hospital, State Key Laboratory of Kidney Diseases, National Clinical Research Center for Kidney Diseases, Beijing, China.

3Department of Emergency, Ningbo No. 2 Hospital, Ningbo, China.

4Department of Cardiology, Hainan Hospital of Chinese PLA General Hospital, Sanya, China.

5Department of Critical Care Medicine, and

6Department of Emergency, Hainan Hospital of Chinese PLA General Hospital, Sanya, China.

7Department of Emergency, Changhai Hospital, Naval Medical University, Shanghai, China.

8Department of Emergency, The Second Naval Hospital of Southern Theater Command of PLA, Sanya, China.

9Heatstroke Treatment and Research Center of PLA, Sanya, China.

10The Second School of Clinical Medicine, Southern Medical University, Guangzhou, China.

11Hainan Medical University, Haikou, China.

12Sanya Nephrology Medical Quality Control Center, Sanya, China.

Address correspondence to: Yizhi Chen, Department of Nephrology, Hainan Hospital of Chinese PLA General Hospital, Sanya, China. Email: yizchen@126.com. Or to: Xiangmei Chen, Senior Department of Nephrology, Chinese PLA General Hospital, Beijing, China. Email: xmchen301@126.com. Or to: Qing Song, Department of Critical Care Medicine, Hainan Hospital of Chinese PLA General Hospital, Sanya, China. Email: songqing3010301@sina.com.

Authorship note: MZ, BW, and DS contributed equally to this work.

Find articles by Qu, Z. in: PubMed | Google Scholar

1Department of Nephrology, Hainan Hospital of Chinese PLA General Hospital, Hainan Province Chen Xiangmei Academician Team Innovation Center for Kidney Diseases Research, Sanya, China.

2Senior Department of Nephrology, Chinese PLA General Hospital, State Key Laboratory of Kidney Diseases, National Clinical Research Center for Kidney Diseases, Beijing, China.

3Department of Emergency, Ningbo No. 2 Hospital, Ningbo, China.

4Department of Cardiology, Hainan Hospital of Chinese PLA General Hospital, Sanya, China.

5Department of Critical Care Medicine, and

6Department of Emergency, Hainan Hospital of Chinese PLA General Hospital, Sanya, China.

7Department of Emergency, Changhai Hospital, Naval Medical University, Shanghai, China.

8Department of Emergency, The Second Naval Hospital of Southern Theater Command of PLA, Sanya, China.

9Heatstroke Treatment and Research Center of PLA, Sanya, China.

10The Second School of Clinical Medicine, Southern Medical University, Guangzhou, China.

11Hainan Medical University, Haikou, China.

12Sanya Nephrology Medical Quality Control Center, Sanya, China.

Address correspondence to: Yizhi Chen, Department of Nephrology, Hainan Hospital of Chinese PLA General Hospital, Sanya, China. Email: yizchen@126.com. Or to: Xiangmei Chen, Senior Department of Nephrology, Chinese PLA General Hospital, Beijing, China. Email: xmchen301@126.com. Or to: Qing Song, Department of Critical Care Medicine, Hainan Hospital of Chinese PLA General Hospital, Sanya, China. Email: songqing3010301@sina.com.

Authorship note: MZ, BW, and DS contributed equally to this work.

Find articles by Chen, L. in: PubMed | Google Scholar

1Department of Nephrology, Hainan Hospital of Chinese PLA General Hospital, Hainan Province Chen Xiangmei Academician Team Innovation Center for Kidney Diseases Research, Sanya, China.

2Senior Department of Nephrology, Chinese PLA General Hospital, State Key Laboratory of Kidney Diseases, National Clinical Research Center for Kidney Diseases, Beijing, China.

3Department of Emergency, Ningbo No. 2 Hospital, Ningbo, China.

4Department of Cardiology, Hainan Hospital of Chinese PLA General Hospital, Sanya, China.

5Department of Critical Care Medicine, and

6Department of Emergency, Hainan Hospital of Chinese PLA General Hospital, Sanya, China.

7Department of Emergency, Changhai Hospital, Naval Medical University, Shanghai, China.

8Department of Emergency, The Second Naval Hospital of Southern Theater Command of PLA, Sanya, China.

9Heatstroke Treatment and Research Center of PLA, Sanya, China.

10The Second School of Clinical Medicine, Southern Medical University, Guangzhou, China.

11Hainan Medical University, Haikou, China.

12Sanya Nephrology Medical Quality Control Center, Sanya, China.

Address correspondence to: Yizhi Chen, Department of Nephrology, Hainan Hospital of Chinese PLA General Hospital, Sanya, China. Email: yizchen@126.com. Or to: Xiangmei Chen, Senior Department of Nephrology, Chinese PLA General Hospital, Beijing, China. Email: xmchen301@126.com. Or to: Qing Song, Department of Critical Care Medicine, Hainan Hospital of Chinese PLA General Hospital, Sanya, China. Email: songqing3010301@sina.com.

Authorship note: MZ, BW, and DS contributed equally to this work.

Find articles by Luo, Q. in: PubMed | Google Scholar

1Department of Nephrology, Hainan Hospital of Chinese PLA General Hospital, Hainan Province Chen Xiangmei Academician Team Innovation Center for Kidney Diseases Research, Sanya, China.

2Senior Department of Nephrology, Chinese PLA General Hospital, State Key Laboratory of Kidney Diseases, National Clinical Research Center for Kidney Diseases, Beijing, China.

3Department of Emergency, Ningbo No. 2 Hospital, Ningbo, China.

4Department of Cardiology, Hainan Hospital of Chinese PLA General Hospital, Sanya, China.

5Department of Critical Care Medicine, and

6Department of Emergency, Hainan Hospital of Chinese PLA General Hospital, Sanya, China.

7Department of Emergency, Changhai Hospital, Naval Medical University, Shanghai, China.

8Department of Emergency, The Second Naval Hospital of Southern Theater Command of PLA, Sanya, China.

9Heatstroke Treatment and Research Center of PLA, Sanya, China.

10The Second School of Clinical Medicine, Southern Medical University, Guangzhou, China.

11Hainan Medical University, Haikou, China.

12Sanya Nephrology Medical Quality Control Center, Sanya, China.

Address correspondence to: Yizhi Chen, Department of Nephrology, Hainan Hospital of Chinese PLA General Hospital, Sanya, China. Email: yizchen@126.com. Or to: Xiangmei Chen, Senior Department of Nephrology, Chinese PLA General Hospital, Beijing, China. Email: xmchen301@126.com. Or to: Qing Song, Department of Critical Care Medicine, Hainan Hospital of Chinese PLA General Hospital, Sanya, China. Email: songqing3010301@sina.com.

Authorship note: MZ, BW, and DS contributed equally to this work.

Find articles by Zhang, J. in: PubMed | Google Scholar

1Department of Nephrology, Hainan Hospital of Chinese PLA General Hospital, Hainan Province Chen Xiangmei Academician Team Innovation Center for Kidney Diseases Research, Sanya, China.

2Senior Department of Nephrology, Chinese PLA General Hospital, State Key Laboratory of Kidney Diseases, National Clinical Research Center for Kidney Diseases, Beijing, China.

3Department of Emergency, Ningbo No. 2 Hospital, Ningbo, China.

4Department of Cardiology, Hainan Hospital of Chinese PLA General Hospital, Sanya, China.

5Department of Critical Care Medicine, and

6Department of Emergency, Hainan Hospital of Chinese PLA General Hospital, Sanya, China.

7Department of Emergency, Changhai Hospital, Naval Medical University, Shanghai, China.

8Department of Emergency, The Second Naval Hospital of Southern Theater Command of PLA, Sanya, China.

9Heatstroke Treatment and Research Center of PLA, Sanya, China.

10The Second School of Clinical Medicine, Southern Medical University, Guangzhou, China.

11Hainan Medical University, Haikou, China.

12Sanya Nephrology Medical Quality Control Center, Sanya, China.

Address correspondence to: Yizhi Chen, Department of Nephrology, Hainan Hospital of Chinese PLA General Hospital, Sanya, China. Email: yizchen@126.com. Or to: Xiangmei Chen, Senior Department of Nephrology, Chinese PLA General Hospital, Beijing, China. Email: xmchen301@126.com. Or to: Qing Song, Department of Critical Care Medicine, Hainan Hospital of Chinese PLA General Hospital, Sanya, China. Email: songqing3010301@sina.com.

Authorship note: MZ, BW, and DS contributed equally to this work.

Find articles by Jin, X. in: PubMed | Google Scholar

1Department of Nephrology, Hainan Hospital of Chinese PLA General Hospital, Hainan Province Chen Xiangmei Academician Team Innovation Center for Kidney Diseases Research, Sanya, China.

2Senior Department of Nephrology, Chinese PLA General Hospital, State Key Laboratory of Kidney Diseases, National Clinical Research Center for Kidney Diseases, Beijing, China.

3Department of Emergency, Ningbo No. 2 Hospital, Ningbo, China.

4Department of Cardiology, Hainan Hospital of Chinese PLA General Hospital, Sanya, China.

5Department of Critical Care Medicine, and

6Department of Emergency, Hainan Hospital of Chinese PLA General Hospital, Sanya, China.

7Department of Emergency, Changhai Hospital, Naval Medical University, Shanghai, China.

8Department of Emergency, The Second Naval Hospital of Southern Theater Command of PLA, Sanya, China.

9Heatstroke Treatment and Research Center of PLA, Sanya, China.

10The Second School of Clinical Medicine, Southern Medical University, Guangzhou, China.

11Hainan Medical University, Haikou, China.

12Sanya Nephrology Medical Quality Control Center, Sanya, China.

Address correspondence to: Yizhi Chen, Department of Nephrology, Hainan Hospital of Chinese PLA General Hospital, Sanya, China. Email: yizchen@126.com. Or to: Xiangmei Chen, Senior Department of Nephrology, Chinese PLA General Hospital, Beijing, China. Email: xmchen301@126.com. Or to: Qing Song, Department of Critical Care Medicine, Hainan Hospital of Chinese PLA General Hospital, Sanya, China. Email: songqing3010301@sina.com.

Authorship note: MZ, BW, and DS contributed equally to this work.

Find articles by Cheng, X. in: PubMed | Google Scholar

1Department of Nephrology, Hainan Hospital of Chinese PLA General Hospital, Hainan Province Chen Xiangmei Academician Team Innovation Center for Kidney Diseases Research, Sanya, China.

2Senior Department of Nephrology, Chinese PLA General Hospital, State Key Laboratory of Kidney Diseases, National Clinical Research Center for Kidney Diseases, Beijing, China.

3Department of Emergency, Ningbo No. 2 Hospital, Ningbo, China.

4Department of Cardiology, Hainan Hospital of Chinese PLA General Hospital, Sanya, China.

5Department of Critical Care Medicine, and

6Department of Emergency, Hainan Hospital of Chinese PLA General Hospital, Sanya, China.

7Department of Emergency, Changhai Hospital, Naval Medical University, Shanghai, China.

8Department of Emergency, The Second Naval Hospital of Southern Theater Command of PLA, Sanya, China.

9Heatstroke Treatment and Research Center of PLA, Sanya, China.

10The Second School of Clinical Medicine, Southern Medical University, Guangzhou, China.

11Hainan Medical University, Haikou, China.

12Sanya Nephrology Medical Quality Control Center, Sanya, China.

Address correspondence to: Yizhi Chen, Department of Nephrology, Hainan Hospital of Chinese PLA General Hospital, Sanya, China. Email: yizchen@126.com. Or to: Xiangmei Chen, Senior Department of Nephrology, Chinese PLA General Hospital, Beijing, China. Email: xmchen301@126.com. Or to: Qing Song, Department of Critical Care Medicine, Hainan Hospital of Chinese PLA General Hospital, Sanya, China. Email: songqing3010301@sina.com.

Authorship note: MZ, BW, and DS contributed equally to this work.

Find articles by Niu, J. in: PubMed | Google Scholar

1Department of Nephrology, Hainan Hospital of Chinese PLA General Hospital, Hainan Province Chen Xiangmei Academician Team Innovation Center for Kidney Diseases Research, Sanya, China.

2Senior Department of Nephrology, Chinese PLA General Hospital, State Key Laboratory of Kidney Diseases, National Clinical Research Center for Kidney Diseases, Beijing, China.

3Department of Emergency, Ningbo No. 2 Hospital, Ningbo, China.

4Department of Cardiology, Hainan Hospital of Chinese PLA General Hospital, Sanya, China.

5Department of Critical Care Medicine, and

6Department of Emergency, Hainan Hospital of Chinese PLA General Hospital, Sanya, China.

7Department of Emergency, Changhai Hospital, Naval Medical University, Shanghai, China.

8Department of Emergency, The Second Naval Hospital of Southern Theater Command of PLA, Sanya, China.

9Heatstroke Treatment and Research Center of PLA, Sanya, China.

10The Second School of Clinical Medicine, Southern Medical University, Guangzhou, China.

11Hainan Medical University, Haikou, China.

12Sanya Nephrology Medical Quality Control Center, Sanya, China.

Address correspondence to: Yizhi Chen, Department of Nephrology, Hainan Hospital of Chinese PLA General Hospital, Sanya, China. Email: yizchen@126.com. Or to: Xiangmei Chen, Senior Department of Nephrology, Chinese PLA General Hospital, Beijing, China. Email: xmchen301@126.com. Or to: Qing Song, Department of Critical Care Medicine, Hainan Hospital of Chinese PLA General Hospital, Sanya, China. Email: songqing3010301@sina.com.

Authorship note: MZ, BW, and DS contributed equally to this work.

Find articles by Xing, Q. in: PubMed | Google Scholar

1Department of Nephrology, Hainan Hospital of Chinese PLA General Hospital, Hainan Province Chen Xiangmei Academician Team Innovation Center for Kidney Diseases Research, Sanya, China.

2Senior Department of Nephrology, Chinese PLA General Hospital, State Key Laboratory of Kidney Diseases, National Clinical Research Center for Kidney Diseases, Beijing, China.

3Department of Emergency, Ningbo No. 2 Hospital, Ningbo, China.

4Department of Cardiology, Hainan Hospital of Chinese PLA General Hospital, Sanya, China.

5Department of Critical Care Medicine, and

6Department of Emergency, Hainan Hospital of Chinese PLA General Hospital, Sanya, China.

7Department of Emergency, Changhai Hospital, Naval Medical University, Shanghai, China.

8Department of Emergency, The Second Naval Hospital of Southern Theater Command of PLA, Sanya, China.

9Heatstroke Treatment and Research Center of PLA, Sanya, China.

10The Second School of Clinical Medicine, Southern Medical University, Guangzhou, China.

11Hainan Medical University, Haikou, China.

12Sanya Nephrology Medical Quality Control Center, Sanya, China.

Address correspondence to: Yizhi Chen, Department of Nephrology, Hainan Hospital of Chinese PLA General Hospital, Sanya, China. Email: yizchen@126.com. Or to: Xiangmei Chen, Senior Department of Nephrology, Chinese PLA General Hospital, Beijing, China. Email: xmchen301@126.com. Or to: Qing Song, Department of Critical Care Medicine, Hainan Hospital of Chinese PLA General Hospital, Sanya, China. Email: songqing3010301@sina.com.

Authorship note: MZ, BW, and DS contributed equally to this work.

Find articles by Tan, X. in: PubMed | Google Scholar

1Department of Nephrology, Hainan Hospital of Chinese PLA General Hospital, Hainan Province Chen Xiangmei Academician Team Innovation Center for Kidney Diseases Research, Sanya, China.

2Senior Department of Nephrology, Chinese PLA General Hospital, State Key Laboratory of Kidney Diseases, National Clinical Research Center for Kidney Diseases, Beijing, China.

3Department of Emergency, Ningbo No. 2 Hospital, Ningbo, China.

4Department of Cardiology, Hainan Hospital of Chinese PLA General Hospital, Sanya, China.

5Department of Critical Care Medicine, and

6Department of Emergency, Hainan Hospital of Chinese PLA General Hospital, Sanya, China.

7Department of Emergency, Changhai Hospital, Naval Medical University, Shanghai, China.

8Department of Emergency, The Second Naval Hospital of Southern Theater Command of PLA, Sanya, China.

9Heatstroke Treatment and Research Center of PLA, Sanya, China.

10The Second School of Clinical Medicine, Southern Medical University, Guangzhou, China.

11Hainan Medical University, Haikou, China.

12Sanya Nephrology Medical Quality Control Center, Sanya, China.

Address correspondence to: Yizhi Chen, Department of Nephrology, Hainan Hospital of Chinese PLA General Hospital, Sanya, China. Email: yizchen@126.com. Or to: Xiangmei Chen, Senior Department of Nephrology, Chinese PLA General Hospital, Beijing, China. Email: xmchen301@126.com. Or to: Qing Song, Department of Critical Care Medicine, Hainan Hospital of Chinese PLA General Hospital, Sanya, China. Email: songqing3010301@sina.com.

Authorship note: MZ, BW, and DS contributed equally to this work.

Find articles by Wang, T. in: PubMed | Google Scholar

1Department of Nephrology, Hainan Hospital of Chinese PLA General Hospital, Hainan Province Chen Xiangmei Academician Team Innovation Center for Kidney Diseases Research, Sanya, China.

2Senior Department of Nephrology, Chinese PLA General Hospital, State Key Laboratory of Kidney Diseases, National Clinical Research Center for Kidney Diseases, Beijing, China.

3Department of Emergency, Ningbo No. 2 Hospital, Ningbo, China.

4Department of Cardiology, Hainan Hospital of Chinese PLA General Hospital, Sanya, China.

5Department of Critical Care Medicine, and

6Department of Emergency, Hainan Hospital of Chinese PLA General Hospital, Sanya, China.

7Department of Emergency, Changhai Hospital, Naval Medical University, Shanghai, China.

8Department of Emergency, The Second Naval Hospital of Southern Theater Command of PLA, Sanya, China.

9Heatstroke Treatment and Research Center of PLA, Sanya, China.

10The Second School of Clinical Medicine, Southern Medical University, Guangzhou, China.

11Hainan Medical University, Haikou, China.

12Sanya Nephrology Medical Quality Control Center, Sanya, China.

Address correspondence to: Yizhi Chen, Department of Nephrology, Hainan Hospital of Chinese PLA General Hospital, Sanya, China. Email: yizchen@126.com. Or to: Xiangmei Chen, Senior Department of Nephrology, Chinese PLA General Hospital, Beijing, China. Email: xmchen301@126.com. Or to: Qing Song, Department of Critical Care Medicine, Hainan Hospital of Chinese PLA General Hospital, Sanya, China. Email: songqing3010301@sina.com.

Authorship note: MZ, BW, and DS contributed equally to this work.

Find articles by Liu, J. in: PubMed | Google Scholar

1Department of Nephrology, Hainan Hospital of Chinese PLA General Hospital, Hainan Province Chen Xiangmei Academician Team Innovation Center for Kidney Diseases Research, Sanya, China.

2Senior Department of Nephrology, Chinese PLA General Hospital, State Key Laboratory of Kidney Diseases, National Clinical Research Center for Kidney Diseases, Beijing, China.

3Department of Emergency, Ningbo No. 2 Hospital, Ningbo, China.

4Department of Cardiology, Hainan Hospital of Chinese PLA General Hospital, Sanya, China.

5Department of Critical Care Medicine, and

6Department of Emergency, Hainan Hospital of Chinese PLA General Hospital, Sanya, China.

7Department of Emergency, Changhai Hospital, Naval Medical University, Shanghai, China.

8Department of Emergency, The Second Naval Hospital of Southern Theater Command of PLA, Sanya, China.

9Heatstroke Treatment and Research Center of PLA, Sanya, China.

10The Second School of Clinical Medicine, Southern Medical University, Guangzhou, China.

11Hainan Medical University, Haikou, China.

12Sanya Nephrology Medical Quality Control Center, Sanya, China.

Address correspondence to: Yizhi Chen, Department of Nephrology, Hainan Hospital of Chinese PLA General Hospital, Sanya, China. Email: yizchen@126.com. Or to: Xiangmei Chen, Senior Department of Nephrology, Chinese PLA General Hospital, Beijing, China. Email: xmchen301@126.com. Or to: Qing Song, Department of Critical Care Medicine, Hainan Hospital of Chinese PLA General Hospital, Sanya, China. Email: songqing3010301@sina.com.

Authorship note: MZ, BW, and DS contributed equally to this work.

Find articles by Li, L. in: PubMed | Google Scholar

1Department of Nephrology, Hainan Hospital of Chinese PLA General Hospital, Hainan Province Chen Xiangmei Academician Team Innovation Center for Kidney Diseases Research, Sanya, China.

2Senior Department of Nephrology, Chinese PLA General Hospital, State Key Laboratory of Kidney Diseases, National Clinical Research Center for Kidney Diseases, Beijing, China.

3Department of Emergency, Ningbo No. 2 Hospital, Ningbo, China.

4Department of Cardiology, Hainan Hospital of Chinese PLA General Hospital, Sanya, China.

5Department of Critical Care Medicine, and

6Department of Emergency, Hainan Hospital of Chinese PLA General Hospital, Sanya, China.

7Department of Emergency, Changhai Hospital, Naval Medical University, Shanghai, China.

8Department of Emergency, The Second Naval Hospital of Southern Theater Command of PLA, Sanya, China.

9Heatstroke Treatment and Research Center of PLA, Sanya, China.

10The Second School of Clinical Medicine, Southern Medical University, Guangzhou, China.

11Hainan Medical University, Haikou, China.

12Sanya Nephrology Medical Quality Control Center, Sanya, China.

Address correspondence to: Yizhi Chen, Department of Nephrology, Hainan Hospital of Chinese PLA General Hospital, Sanya, China. Email: yizchen@126.com. Or to: Xiangmei Chen, Senior Department of Nephrology, Chinese PLA General Hospital, Beijing, China. Email: xmchen301@126.com. Or to: Qing Song, Department of Critical Care Medicine, Hainan Hospital of Chinese PLA General Hospital, Sanya, China. Email: songqing3010301@sina.com.

Authorship note: MZ, BW, and DS contributed equally to this work.

Find articles by Song, Q. in: PubMed | Google Scholar

1Department of Nephrology, Hainan Hospital of Chinese PLA General Hospital, Hainan Province Chen Xiangmei Academician Team Innovation Center for Kidney Diseases Research, Sanya, China.

2Senior Department of Nephrology, Chinese PLA General Hospital, State Key Laboratory of Kidney Diseases, National Clinical Research Center for Kidney Diseases, Beijing, China.

3Department of Emergency, Ningbo No. 2 Hospital, Ningbo, China.

4Department of Cardiology, Hainan Hospital of Chinese PLA General Hospital, Sanya, China.

5Department of Critical Care Medicine, and

6Department of Emergency, Hainan Hospital of Chinese PLA General Hospital, Sanya, China.

7Department of Emergency, Changhai Hospital, Naval Medical University, Shanghai, China.

8Department of Emergency, The Second Naval Hospital of Southern Theater Command of PLA, Sanya, China.

9Heatstroke Treatment and Research Center of PLA, Sanya, China.

10The Second School of Clinical Medicine, Southern Medical University, Guangzhou, China.

11Hainan Medical University, Haikou, China.

12Sanya Nephrology Medical Quality Control Center, Sanya, China.

Address correspondence to: Yizhi Chen, Department of Nephrology, Hainan Hospital of Chinese PLA General Hospital, Sanya, China. Email: yizchen@126.com. Or to: Xiangmei Chen, Senior Department of Nephrology, Chinese PLA General Hospital, Beijing, China. Email: xmchen301@126.com. Or to: Qing Song, Department of Critical Care Medicine, Hainan Hospital of Chinese PLA General Hospital, Sanya, China. Email: songqing3010301@sina.com.

Authorship note: MZ, BW, and DS contributed equally to this work.

Find articles by Chen, X. in: PubMed |