Sundar JS, Srijayanth P, Karthikeyan PR, Hemapriya AS, Valarmathi S, Kalpana S, et al. Risk factors for cervical cancer among women reporting government tertiary care hospitals in Chennai, Tamil Nadu, Southern India: a cross-sectional study. Int J Res Med Sci. 2020;12(12):4611–6.
Arbyn M, Weiderpass E, Bruni L, De Sanjosé S, Saraiya M, Ferlay J, et al. Estimates of incidence and mortality of cervical cancer in 2018: a worldwide analysis. Lancet Glob Health. 2020;8(2):e191-203.
Tamilarasi R, Maheshwari L, Siddharth R. A study of awareness on cervical cancer and prevalence of pathological leucorrhoea among women in rural Chennai. Int J Community Med Public Health. 2018;5(5):2118.
Singh M, Jha RP, Shri N, Bhattacharyya K, Patel P, Dhamnetiya D. Secular trends in incidence and mortality of cervical cancer in India and its states, 1990–2019: data from the global burden of disease 2019 study. BMC Cancer. 2022;22(1):149.
Article PubMed PubMed Central Google Scholar
Wang LN, Wang F, Liu J, Jin YH, Fang C, Ren XQ. CYP1A1 Ile462Val polymorphism is associated with cervical cancer risk in caucasians not Asians: a meta-analysis. Front Physiol. 2017;18(8):1081.
Kiruthiga P, Kannan MR, Saraswathi C, Pandian SK, Pandima K. CYP1A1 gene polymorphisms: lack of association with breast cancer susceptibility in the southern region (Madurai) of India. Asian Pac J Cancer Prev. 2011;12:2133.
Ahangar N. Frequency evaluation of T6235C (m1) and A4889G (m2) polymorphisms of CYP1A1 gene in a healthy population from the west of mazandaran province. Iran Cell Mol Biol. 2016;62(7):90.
Bag A, Jyala N, Bag N. Cytochrome P450 1A1 genetic polymorphisms as cancer biomarkers. Indian J Cancer. 2015;52(4):479.
Article PubMed CAS Google Scholar
Joseph T, Chacko P, Wesley R, Jayaprakash PG, James FV, Pillai MR. Germline genetic polymorphisms of CYP1A1, GSTM1 and GSTT1 genes in Indian cervical cancer: associations with tumor progression, age and human papillomavirus infection. Gynecol Oncol. 2006;101(3):411–7.
Article PubMed CAS Google Scholar
Gutman G, Morad T, Peleg B, Peretz C, Bar-Am A, Safra T, et al. CYP1A1 and CYP2D6 Gene Polymorphisms in Israeli Jewish Women With Cervical Cancer. Int J Gynecol Cancer. 2009;19(8):1300–2.
Taskiran C, Aktas D, Yigit-Celik N, Alikasifoglu M, Yuce K, Tunçbilek E, et al. CYP1A1 gene polymorphism as a risk factor for cervical intraepithelial neoplasia and invasive cervical cancer. Gynecol Oncol. 2006;101(3):503–6.
Article PubMed CAS Google Scholar
Abbas M, Srivastava K, Imran M, Banerjee M. Association of CYP1A1 gene variants rs4646903 (T>C) and rs1048943 (A>G) with cervical cancer in a North Indian population. Eur J Obstet Gynecol Reprod Biol. 2014;176:68–74.
Article PubMed CAS Google Scholar
Barek MdA, Basher MA, Aziz MdA, Hossen MdS, Jahan N, Afroz N, et al. Assessment of the association of CYP1A1 gene polymorphisms with the susceptibility of cervical cancer: A case-control study and meta-analysis. Heliyon. 2023;9(7):e17712.
Article PubMed PubMed Central CAS Google Scholar
Hirata H, Hinoda Y, Okayama N, Suehiro Y, Kawamoto K, Kikuno N, et al. CYP1A1, SULT1A1, and SULT1E1 polymorphisms are risk factors for endometrial cancer susceptibility. Cancer. 2008;112(9):1964–73.
Article PubMed CAS Google Scholar
Autrup H. Genetic polymorphisms in human xenobiotica metabolizing enzymes as susceptibility factors in toxic response. Mutat Res Toxicol Environ Mutagen. 2000;464(1):65–76.
Jain V, Ratre YK, Amle D, Mishra PK, Patra PK. Polymorphism of CYP1A1 gene variants rs4646903 and rs1048943 relation to the incidence of cervical cancer in Chhattisgarh. Environ Toxicol Pharmacol. 2017;52:188–92.
Article PubMed CAS Google Scholar
Datkhile KD, Patil SR, Patil MN, Durgawale PP, Jagdale NJ, Deshmukh VN, et al. Genetic polymorphisms of CYP1A, CYP1B, CYP2C and risk of cervical cancer among rural population of Maharashtra: findings from a hospital-based case-control study. J Cancer Res Ther. 2023;19(7):1925–30.
Article PubMed CAS Google Scholar
Helaoui A, Sfar S, Boudhiba N, Dehghanian F, Dehbashi M, Bouchahda H, et al. Association of xenobiotic-metabolizing genes polymorphisms with cervical cancer risk in the Tunisian population. Mol Biol Rep. 2023;50(2):949–59.
Article PubMed CAS Google Scholar
Satinder K, Sobti RC, Pushpinder K. Impact 0f single nucleotide polymorphism in chemical metabolizing genes and exposure to wood smoke on risk of cervical cancer in North-Indian women. Exp Oncol. 2017;39(1):69–74.
Article PubMed CAS Google Scholar
Nath N, Mishra P, Panda AK, Mishra R. Polymorphisms and haplotypes of TLR4, TLR9 and CYP1A1 genes possibly interfere with high-risk human papillomavirus infection and cervical cancer susceptibility in Jharkhand, India. Int Immunopharmacol. 2020;88:106925.
Article PubMed CAS Google Scholar
Sudenga SL, Shrestha S, Macaluso M, Partridge EE, Johanning GL, Piyathilake CJ. Functional variants in CYP1A1 and GSTM1 are associated with clearance of cervical HPV infection. Gynecol Oncol. 2014;135(3):560–4.
Article PubMed PubMed Central CAS Google Scholar
Xia L, Gao J, Liu Y, Wu K. Significant association between CYP1A1 T3801C polymorphism and cervical neoplasia risk: a systematic review and meta-analysis. Tumour Biol. 2013;34(1):223–30.
Article PubMed CAS Google Scholar
Matos A, Castelão C, Pereira Da Silva A, Alho I, Bicho M, Medeiros R, et al. Epistatic Interaction of CYP1A1 and COMT Polymorphisms in Cervical Cancer. Pallottini V, editor. Oxid Med Cell Longev. 2016; 2016(1):2769804.
Von Keyserling H, Bergmann T, Schuetz M, Schiller U, Stanke J, Hoffmann C, et al. Analysis of4 single-nucleotide polymorphisms in relation to cervical dysplasia and cancer development using a high-through put ligation-detection reaction procedure. Int J Gynecol Cancer. 2011;21(9):1664–71.
Juárez-Cedillo T, Vallejo M, Fragoso JM, Hernández-Hernández DM, Rodríguez-Pérez JM, Sánchez-García S, et al. The risk of developing cervical cancer in Mexican women is associated to CYP1A1 MspI polymorphism. Eur J Cancer. 2007;43(10):1590–5.
Sugawara T, Nomura E, Sagawa T, Sakuragi N, Fujimoto S. CYP1A1 polymorphism and risk of gynecological malignancy in Japan. Int J Gynecol Cancer. 2003;13(6):785–90.
Article PubMed CAS Google Scholar
Li S, Li G, Kong F, Liu Z, Li N, Li Y, et al. The association of CYP 1A1 gene with cervical cancer and additional SNP – SNP interaction in Chinese women. J Clin Lab Anal. 2016;30(6):1220–5.
Article PubMed PubMed Central CAS Google Scholar
Das AP, Saini S, Agarwal SM. A comprehensive meta-analysis of non-coding polymorphisms associated with precancerous lesions and cervical cancer. Genomics. 2022;114(3):110323.
Article PubMed CAS Google Scholar
Sengupta D, Guha U, Mitra S, Ghosh S, Bhattacharjee S, Sengupta M. Meta-Analysis of polymorphic variants conferring genetic risk to cervical cancer in Indian women supports CYP1A1 as an important associated locus. Asian Pac J Cancer Prev. 2018 [cited 2025 Jun 26];19(8). Available from: https://doi.org/10.22034/APJCP.2018.19.8.2071
Yang S, Jia C, Zhu H, Han S. CYP1A1 Ile462Val polymorphism and cervical cancer: evidence from a meta-analysis. Tumor Biol. 2012;33(6):2265–72.
Wang S, Sun H, Jia Y, Tang F, Zhou H, Li X, et al. Association of 42 SNPs with genetic risk for cervical cancer: an extensive meta-analysis. BMC Med Genet. 2015;16(1):25.
Article PubMed PubMed Central Google Scholar
Ding B, Sun W, Han S, Cai Y, Ren M, Shen Y. Cytochrome P450 1A1 gene polymorphisms and cervical cancer risk: a systematic review and meta-analysis. Medicine (Baltimore). 2018;97(13):e0210.
Article PubMed PubMed Central CAS Google Scholar
He XF, Wei W, Liu ZZ, Shen XL, Yang XB, Wang SL, et al. Association between the CYP1A1 T3801C polymorphism and risk of cancer: evidence from 268 case–control studies. Gene. 2014;534(2):324–44.
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