Garg S, Serruys PW. Coronary stents: current status. J Am Coll Cardiol. 2010;56:S1-42.

Article  CAS  PubMed  Google Scholar 

Moses JW, Leon MB, Popma JJ, Fitzgerald PJ, Holmes DR, O’Shaughnessy C, et al. Sirolimus-eluting stents versus standard stents in patients with stenosis in a native coronary artery. N Engl J Med. 2003;349:1315–23.

Article  CAS  PubMed  Google Scholar 

Marx SO, Jayaraman T, Go LO, Marks AR. Rapamycin-FKBP inhibits cell cycle regulators of proliferation in vascular smooth muscle cells. Circ Res. 1995;76:412–7.

Article  CAS  PubMed  Google Scholar 

Poon M, Marx SO, Gallo R, D’Agati V, Leya F, Sclar G, et al. Rapamycin inhibits vascular smooth muscle cell migration. J Clin Invest. 1996;98:2277–83.

Article  CAS  PubMed  PubMed Central  Google Scholar 

Joner M, Finn AV, Farb A, Mont EK, Kolodgie FD, Ladich E, et al. Pathology of drug-eluting stents in humans: delayed healing and late thrombotic risk. J Am Coll Cardiol. 2006;48:193–202.

Article  PubMed  Google Scholar 

Finn AV, Joner M, Nakazawa G, Kolodgie F, Newell J, John MC, et al. Pathological correlates of late drug-eluting stent thrombosis: strut coverage as a marker of endothelialization. Circulation. 2007;115:2435–41.

Article  PubMed  Google Scholar 

Byrne RA, Joner M, Kastrati A. Stent thrombosis and restenosis: what have we learned and where are we going? Eur Heart J. 2015;36:3320–31.

Article  PubMed  PubMed Central  Google Scholar 

Wessely R, Kastrati A, Mehilli J, Schömig A, Dirschinger J, Pache J, et al. Sirolimus and paclitaxel on polymer-based drug-eluting stents: similar inhibition of neointimal hyperplasia but differential effects on fibrin deposition and inflammation. Atherosclerosis. 2006;188:287–95.

Google Scholar 

Yang Y, Zhao J, Jiang C, Shi Y, Wang L, Sun S, et al. WKYMVm works by targeting immune cells. J Inflamm Res. 2023;16:45–55.

Article  CAS  PubMed  PubMed Central  Google Scholar 

Heo SC, Kwon YW, Jang IH, Jeong GO, Lee HY, Kim HS, et al. WKYMVm-induced activation of formyl peptide receptor 2 stimulates ischemic neovasculogenesis by promoting homing of endothelial colony-forming cells. Stem Cells. 2014;32:779–90.

Article  CAS  PubMed  Google Scholar 

Kim YE, Park WS, Ahn SY, Choi SJ, Sung SI, Chang YS, et al. WKYMVm hexapeptide, a strong formyl peptide receptor 2 agonist, attenuates hyperoxia-induced lung injuries in newborn mice. Sci Rep. 2019;9:6815.

Article  PubMed  PubMed Central  Google Scholar 

Heo SK, Lee SY, Kim EK, Noh GW, Lee S, Bae YS, et al. Formyl peptide receptor 2 agonist WKYMVm promotes angiogenesis by enhancing endothelial progenitor cell chemotaxis, proliferation, and differentiation. Biochem Biophys Res Commun. 2014;447:512–8.

Google Scholar 

Kastrati A, Mehilli J, Dirschinger J, Dibra A, Pache J, Schühlen H, et al. Intracoronary stenting and angiographic results: strut thickness effect on restenosis outcome (ISAR-STEREO) trial. Circulation. 2001;103:2816–21.

Article  CAS  PubMed  Google Scholar 

Dash M, Chiellini F, Ottenbrite RM, Chiellini E. Chitosan—a versatile semi-synthetic polymer in biomedical applications. Prog Polym Sci. 2011;36:981–1014.

Article  CAS  Google Scholar 

Geng H, Song H, Qi J, Cui D. Sustained release of VEGF from PLGA nanoparticles embedded thermo-sensitive hydrogel in full-thickness porcine bladder acellular matrix. Nanoscale Res Lett. 2011;6:312.

Article  PubMed  PubMed Central  Google Scholar 

Al-Nemrawi NK, Alshraiedeh NH, Zayed GM, Altamimi MA. Low molecular weight chitosan-coated PLGA nanoparticles for pulmonary delivery of tobramycin. Pharmaceuticals (Basel). 2018;11:28.

Article  PubMed  PubMed Central  Google Scholar 

Choi YH, Heo SC, Kwon YW, Kim S, Kim CD, Bae YS, et al. Injectable PLGA microspheres encapsulating WKYMVm peptide for neovascularization. Acta Biomater. 2015;25:76–85.

Article  CAS  PubMed  Google Scholar 

Bae IH, Lim KS, Park DS, Lee SY, Jang EJ, Jeong MH, et al. Mechanical behavior and in vivo properties of newly designed bare metal stent for enhanced flexibility. J Ind Eng Chem. 2015;21:1295–300.

Article  CAS  Google Scholar 

Schwartz RS, Huber KC, Murphy JG, Edwards WD, Camrud AR, Vlietstra RE, et al. Restenosis and the proportional neointimal response to coronary artery injury: results in a porcine model. J Am Coll Cardiol. 1992;19:267–74.

Article  CAS  PubMed  Google Scholar 

Schwartz RS, Edelman ER, Carter A, Chronos N, Rogers C, Robinson KA, et al. Drug-eluting stents in preclinical studies: updated consensus recommendations for preclinical evaluation. Circ Cardiovasc Interv. 2008;1:143–53.

Article  PubMed  PubMed Central  Google Scholar 

Suzuki T, Kopia G, Hayashi S, Bailey LR, Llanos G, Wilensky R, et al. Stent-based delivery of sirolimus reduces neointimal formation in a porcine coronary model. Circulation. 2001;104:1188–93.

Article  CAS  PubMed  Google Scholar 

Basalus MW, Ankone MJ, van Houwelingen GK, de Man FH, von Birgelen C. Coating irregularities of durable polymer-based drug-eluting stents as assessed by scanning electron microscopy. EuroIntervention. 2009;5:157–65.

Article  PubMed  Google Scholar 

Jia Z, Ma C, Zhang H. PLGA coatings and PLGA drug-loading coatings for cardiac stent samples: degradation characteristics and blood compatibility. Coatings. 2021;11:1427.

Article  CAS  Google Scholar 

Xu W, Sasaki M, Niidome T. Sirolimus release from biodegradable polymers for coronary stent application: a review. Pharmaceutics. 2022;14:492.

Article  CAS  PubMed  PubMed Central  Google Scholar 

Costa MA, Simon DI. Molecular basis of restenosis and drug-eluting stents. Circulation. 2005;111:2257–73.

Article  PubMed  Google Scholar 

Jang EJ, Bae IH, Park DS, Lee SY, Lim KS, Jeong MH, et al. Effect of a novel peptide, WKYMVm- and sirolimus-coated stent on re-endothelialization and anti-restenosis. J Mater Sci Mater Med. 2015;26:251.

Article  PubMed  Google Scholar 

Choi YH, Jang IH, Heo SC, Kim JH, Hwang NS. Biomedical therapy using synthetic WKYMVm hexapeptide. Korean J Physiol Pharmacol. 2016;20:567–76.

Google Scholar 

Park DS, Oh S, Jin YJ, Na MH, Kim MK, Jeong MH, et al. Preliminary investigation on efficacy and safety of substance P-coated stent for promoting re-endothelialization: a porcine coronary artery restenosis model. Tissue Eng Regen Med. 2024;21:53–64.

Article  CAS  PubMed  Google Scholar 

Jang TS, Lee JH, Kim S, Park C, Song J, Jae HJ, et al. Ta ion–implanted nanoridge platform for enhanced vascular responses. Biomaterials. 2019;223:119461.

Article  CAS  PubMed  Google Scholar 

Cheon KH, Park C, Kang MH, Park S, Kim J, Jeong SH, et al. A combination strategy of functionalized polymer coating with Ta ion implantation for multifunctional and biodegradable vascular stents. J Magnes Alloys. 2021;9:2194–206.

Article  CAS  Google Scholar 

Park DS, Lim KS, Kim MK, Sim DS, Hong YJ, Jeong MH, et al. Anti-restenotic and anti-thrombotic effect of polymer-free N-TiO2 film-based tacrolimus-eluting stent in a porcine model. Mater Today Commun. 2019;22:100777.

Article  Google Scholar 

Park DS, Na MH, Jin YJ, Kim MK, Sim DS, Jeong MH, et al. Efficacy and safety evaluation of tacrolimus-eluting stent in a porcine coronary artery model. Tissue Eng Regen Med. 2024;21:723–35.

Article  CAS  PubMed  PubMed Central  Google Scholar 

Aoki J, Serruys PW, van Beusekom H, Ong AT, McFadden EP, Sianos G, et al. Endothelial progenitor cell capture by stents coated with antibody against CD34: the HEALING-FIM (Healthy Endothelial Accelerated Lining Inhibits Neointimal Growth-First In Man) Registry. J Am Coll Cardiol. 2005;45:1574–9.

Article  CAS  PubMed