Plastic and reconstructive surgery in spinal sarcoma resection: a review of indications, techniques, and outcomes

Martinez C, Abdulwadood I, Winocour S et al (2024) Spino-Plastic Surgery: Addressing Spinal Tumors with New Techniques. Cancers (Basel) 16(23):4088 Published 2024 Dec 6. https://doi.org/10.3390/cancers16234088

Article  CAS  PubMed  PubMed Central  Google Scholar 

Brigham and Women’s Hospital. Spinal tumor overview: spinal tumor symptoms, diagnosis & treatment. Accessed January 15 (2025) https://www.brighamandwomens.org/spinal-tumor-program/spinal-cord-and-column-tumors

Franck P, Bernstein JL, Cohen LE, Härtl R, Baaj AA, Spector JA (2018) Local muscle flaps minimize post-operative wound morbidity in patients with neoplastic disease of the spine. Clin Neurol Neurosurg 171:100–105. https://doi.org/10.1016/j.clineuro.2018.05.022

Article  PubMed  Google Scholar 

Mericli AF, Boukovalas S, Rhines LD, Adelman DM, Hanasono MM, Chang EI (2020) Free Fibula Flap for Restoration of Spinal Stability after Oncologic Vertebrectomy Is Predictive of Bony Union. Plast Reconstr Surg 145(1):219–229. https://doi.org/10.1097/PRS.0000000000006382

Article  CAS  PubMed  Google Scholar 

Schroeder C, de Lomba WC, Leary OP et al (2024) Multidisciplinary surgical considerations for en bloc resection of sacral chordoma: review of recent advances and a contemporary single-center series. Neurosurg Focus 56(5):E7. https://doi.org/10.3171/2024.2.FOCUS23926

Article  PubMed  Google Scholar 

Yang H, Hou K, Lu N, Xiao S, Wang Y (2016) En bloc spondylectomy combined with chest wall excision for spinal tumor via a modified posterior approach: a retrospective study on 21 patients. Clin Neurol Neurosurg 140:91–96. https://doi.org/10.1016/j.clineuro.2015.11.018

Article  PubMed  Google Scholar 

Dolan RT, Butler JS, Wilson-MacDonald J et al (2016) Quality of Life and Surgical Outcomes After Soft-Tissue Reconstruction of Complex Oncologic Defects of the Spine and Sacrum. J Bone Joint Surg Am 98(2):117–126. https://doi.org/10.2106/JBJS.N.01353

Article  PubMed  Google Scholar 

Dickey ID, Hugate RR Jr, Fuchs B, Yaszemski MJ, Sim FH (2005) Reconstruction after total sacrectomy: early experience with a new surgical technique. Clin Orthop Relat Res 438:42–50. https://doi.org/10.1097/01.blo.0000180054.76969.41

Article  PubMed  Google Scholar 

Coon D, Calotta NA, Broyles JM, Sacks JM (2016) Use of Biological Tissue Matrix in Postneurosurgical Posterior Trunk Reconstruction Is Associated with Higher Wound Complication Rates. Plast Reconstr Surg 138(1):104e–110e. https://doi.org/10.1097/PRS.0000000000002244

Article  CAS  PubMed  Google Scholar 

Chang DW, Friel MT, Youssef AA (2007) Reconstructive strategies in soft tissue reconstruction after resection of spinal neoplasms. Spine (Phila Pa 1976) 32(10):1101–1106. https://doi.org/10.1097/01.brs.0000261555.72265.3f

Article  PubMed  Google Scholar 

Leary OP, Liu DD, Boyajian MK et al (2020) Complex wound closure by plastic surgery following resection of spinal neoplasms minimizes postoperative wound complications in high-risk patients. J Neurosurg Spine 33(1):77–86 Published 2020 Feb 28. https://doi.org/10.3171/2019.12.SPINE191238

Article  PubMed  Google Scholar 

Falade IO, Knox JA, Piper ML, Hoffman WY, Hansen SL (2024) Soft Tissue Reconstruction After Sacral Neoplasm Resection: The University of California San Francisco Experience. Ann Plast Surg 92(5S Suppl 3):S320–S326. https://doi.org/10.1097/SAP.0000000000003803

Article  CAS  PubMed  Google Scholar 

Kim JE, Pang J, Christensen JM et al (2015) Soft-tissue reconstruction after total en bloc sacrectomy. J Neurosurg Spine 22(6):571–581. https://doi.org/10.3171/2014.10.SPINE14114

Article  PubMed  Google Scholar 

Garvey PB, Rhines LD, Dong W, Chang DW (2010) Immediate soft-tissue reconstruction for complex defects of the spine following surgery for spinal neoplasms. Plast Reconstr Surg 125(5):1460–1466. https://doi.org/10.1097/PRS.0b013e3181d5125e

Article  CAS  PubMed  Google Scholar 

Glennie RA, Rampersaud YR, Boriani S et al (2016) A Systematic Review With Consensus Expert Opinion of Best Reconstructive Techniques After Osseous En Bloc Spinal Column Tumor Resection. Spine (Phila Pa 1976) 41(Suppl 20):S205–S211. https://doi.org/10.1097/BRS.0000000000001835

Article  PubMed  Google Scholar 

Massaad E, Patel SS, Sten M et al (2024) Pedicled omental flaps for complex wound reconstruction following surgery for primary spine tumors of the mobile spine and sacrum. J Neurosurg Spine 41(2):283–291 Published 2024 May 24. https://doi.org/10.3171/2024.2.SPINE231134

Article  PubMed  Google Scholar 

Leary OP, Setty A, Gong JH, Ali R, Fridley JS, Fisher CG, Sahgal A, Rhines LD, Reynolds JJ, Lazáry Á, Laufer I, Gasbarrini A, Dea N, Verlaan JJ, Bettegowda C, Boriani S, Mesfin A, Luzzati A, Shin JH, Cecchinato R, Hornicek FJ, Goodwin ML, Gokaslan ZL (2025) Prevention and Management of Posterior Wound Complications Following Oncologic Spine Surgery: Narrative Review of Available Evidence and Proposed Clinical Decision-Making Algorithm. Global Spine J 15(1suppl):143S–156S. https://doi.org/10.1177/21925682241237486

Article  PubMed  PubMed Central  Google Scholar 

Carcione T, Callas B, Thiara J, Jungbauer WN, Jeger J, Reece E (2026) Precision-Oriented Reconstruction After Spinal Sarcoma Resection: Integrating Surgical Strategy, Biologic Risk, and Emerging Technologies. Cancers (Basel) 18(10):1555. https://doi.org/10.3390/cancers18101555

Article  CAS  PubMed  PubMed Central  Google Scholar 

Hersh AM, Pennington Z, Schilling AT et al (2021) Plastic surgery wound closure following resection of spinal metastases. Clin Neurol Neurosurg 207:106800. https://doi.org/10.1016/j.clineuro.2021.106800

Article  PubMed  Google Scholar 

Sambri A, Gasbarrini A, Cialdella S, De Iaco P, Boriani S (2017) Pedicled omental flaps in the treatment of complex spinal wounds after en bloc resection of spine tumors. J Plast Reconstr Aesthet Surg 70(9):1267–1271. https://doi.org/10.1016/j.bjps.2017.06.011

Article  PubMed  Google Scholar 

Diaz J, McDonald WS, Armstrong M, Eismont F, Hellinger M, Thaller S (2003) Reconstruction after extirpation of sacral malignancies. Ann Plast Surg 51(2):126–129. https://doi.org/10.1097/01.SAP.0000063754.39566.5C

Article  PubMed  Google Scholar 

Wuisman P, Lieshout O, Sugihara S, van Dijk M (2000) Total sacrectomy and reconstruction: oncologic and functional outcome. Clin Orthop Relat Res 381192–203. https://doi.org/10.1097/00003086-200012000-00023

Leary OP, Crozier J, Liu DD et al (2021) Three-Dimensional Printed Anatomic Modeling for Surgical Planning and Real-Time Operative Guidance in Complex Primary Spinal Column Tumors: Single-Center Experience and Case Series. World Neurosurg 145:e116–e126. https://doi.org/10.1016/j.wneu.2020.09.145

Article  PubMed  Google Scholar 

Mericli AF, Murariu D, Nemir S et al (2020) Soft-Tissue Reconstruction after Composite Vertebrectomy and Chest Wall Resection for Spinal Tumors. Plast Reconstr Surg 145(5):1275–1286. https://doi.org/10.1097/PRS.0000000000006792

Article  CAS  PubMed  Google Scholar 

Dalton T, Darner G, McCray E et al (2024) Prophylactic Muscle Flaps Decrease Wound Complication Rates in Patients with Oncologic Spine Disease. Plast Reconstr Surg 153(1):221–231. https://doi.org/10.1097/PRS.0000000000010568

Article  CAS  PubMed  Google Scholar 

Mericli AF, Rhines L, Bird J, Liu J, Selber JC (2019) Immediate Reconstruction of Oncologic Spinal Wounds Is Cost-Effective Compared with Conventional Primary Wound Closure. Plast Reconstr Surg 144(5):1182–1195. https://doi.org/10.1097/PRS.0000000000006170

Article  CAS  PubMed  Google Scholar 

Kim DK, Tang AJ, Chan AK, Rohde CH (2024) Racial and ethnic disparities in reception of muscle flap closure during oncologic spinal surgery. J Plast Reconstr Aesthet Surg 96:114–117. https://doi.org/10.1016/j.bjps.2024.07.036

Article  PubMed  Google Scholar 

Thalji SZ, Ethun CG, Tsai S et al (2023) Outcomes of plastic surgical reconstruction in extremity and truncal soft tissue sarcoma: Results from the US Sarcoma Collaborative. J Surg Oncol 127(4):550–559. https://doi.org/10.1002/jso.27169

Article  PubMed  Google Scholar 

Kaiser R, Gasbarrini A, Pasini S et al (2025) New options and techniques in reconstructing the sacrum. Eur Spine J Published online June 24. https://doi.org/10.1007/s00586-025-09058-7

Thomas B, Bigdeli AK, Nolte S et al (2022) The Therapeutic Role of Plastic and Reconstructive Surgery in the Interdisciplinary Treatment of Soft-Tissue Sarcomas in Germany-Cross-Sectional Results of a Prospective Nationwide Observational Study (PROSa). Cancers (Basel) 14(17):4312 Published 2022 Sep 2. https://doi.org/10.3390/cancers14174312

Article  PubMed  PubMed Central  Google Scholar 

Azzi AJ, Zhou S, Safran T, Xu L, Alnaif N, Zadeh T (2019) Vascularized Tissue Reconstruction in Previously Irradiated Sarcoma Defects. Ann Plast Surg 82(1):89–92.

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