Bangalore Krishna K, Witchel SF (2024) Normal puberty. Endocrinol Metab Clin North Am 53:183–194. https://doi.org/10.1016/j.ecl.2024.01.001
Willemars MMA, Nabben M, Verdonschot JAJ, Hoes MF (2022) Evaluation of the interaction of sex hormones and cardiovascular function and health. Curr Heart Fail Rep 19:200–212. https://doi.org/10.1007/s11897-022-00555-0
Article CAS PubMed PubMed Central Google Scholar
Wang C, Xu Y (2019) Mechanisms for sex differences in energy homeostasis. J Mol Endocrinol 62:R129–R143. https://doi.org/10.1530/JME-18-0165
Article CAS PubMed PubMed Central Google Scholar
Mason KA, Schoelwer MJ, Rogol AD (2020) Androgens during Infancy, Childhood, and adolescence: physiology and use in clinical practice. Endocr Rev 41. https://doi.org/10.1210/endrev/bnaa003
Liu X, Lin L, Cai Q, Li C, Xu H, Zeng R, Zhang M, Qiu X, Chen S, Zhang X, Huang L, Liang W, He J (2023) Do testosterone and sex hormone-binding Globulin affect cancer risk? A Mendelian randomization and bioinformatics study. Aging Male 26:2261524. https://doi.org/10.1080/13685538.2023.2261524
Article CAS PubMed Google Scholar
Xu K, Fu Y, Cao B, Zhao M (2022) Association of sex hormones and sex Hormone-Binding Globulin levels with bone mineral density in adolescents aged 12–19 years. Front Endocrinol (Lausanne) 13:891217. https://doi.org/10.3389/fendo.2022.891217
Hess RA, Cooke PS (2018) Estrogen in the male: a historical perspective. Biol Reprod 99:27–44. https://doi.org/10.1093/biolre/ioy043
Article PubMed PubMed Central Google Scholar
Tariq H, Zahid N, Amir D, Ashraf M, Aftab MA, Yousaf S, Rehman R (2021) Estimation of folic acid/micro nutrients levels; does it reflect sperm parameters. Int J Clin Pract 75:e13790. https://doi.org/10.1111/ijcp.13790
Article CAS PubMed Google Scholar
Saylam B, Cayan S (2020) Do antioxidants improve serum sex hormones and total motile sperm count in idiopathic infertile men? Turk J Urol 46:442–448. https://doi.org/10.5152/tud.2020.20296
Article PubMed PubMed Central Google Scholar
Chen C, Zhai H, Cheng J, Weng P, Chen Y, Li Q, Wang C, Xia F, Wang N, Lu Y (2019) Causal link between vitamin D and total testosterone in men: A Mendelian randomization analysis. J Clin Endocrinol Metab 104:3148–3156. https://doi.org/10.1210/jc.2018-01874
Yu C, Liu K, Yao W, Tang D (2025) Associations between the intake of single and multiple dietary vitamins and depression risk among populations with chronic kidney disease. Front Nutr 12:1492829. https://doi.org/10.3389/fnut.2025.1492829
Article CAS PubMed PubMed Central Google Scholar
National Health and Nutrition Examination Survey Available from: www.cdc.gov/nchs/nhanes/?CDC_AAref_Val=www.cdc.gov/nchs/nhanes/index.htm
NHANES 2003–2004 (2004) Laboratory Methods. Available from: wwwn.cdc.gov/nchs/nhanes/continuousnhanes/labmethods.aspx?Cycle=2003-
Stevens GA, Bennett JE, Hennocq Q, Lu Y, De-Regil LM, Rogers L, Danaei G, Li G, White RA, Flaxman SR, Oehrle SP, Finucane MM, Guerrero R, Bhutta ZA, Then-Paulino A, Fawzi W, Black RE, Ezzati M (2015) Trends and mortality effects of vitamin A deficiency in children in 138 low-income and middle-income countries between 1991 and 2013: a pooled analysis of population-based surveys. Lancet Glob Health 3:e528–536. https://doi.org/10.1016/S2214-109X(15)00039-X
Szlagatys-Sidorkiewicz A, Brzezinski M, Jankowska A, Metelska P, Slominska-Fraczek M, Socha P (2017) Long-term effects of vitamin D supplementation in vitamin D deficient obese children participating in an integrated weight-loss programme (a double-blind placebo-controlled study) - rationale for the study design. BMC Pediatr 17:97. https://doi.org/10.1186/s12887-017-0851-7
Article CAS PubMed PubMed Central Google Scholar
Cashman KD, Dowling KG, Skrabakova Z, Gonzalez-Gross M, Valtuena J, De Henauw S, Moreno L, Damsgaard CT, Michaelsen KF, Molgaard C, Jorde R, Grimnes G, Moschonis G, Mavrogianni C, Manios Y, Thamm M, Mensink GB, Rabenberg M, Busch MA, Cox L, Meadows S, Goldberg G, Prentice A, Dekker JM, Nijpels G, Pilz S, Swart KM, van Schoor NM, Lips P, Eiriksdottir G, Gudnason V, Cotch MF, Koskinen S, Lamberg-Allardt C, Durazo-Arvizu RA, Sempos CT, Kiely M (2016) Vitamin D deficiency in europe: pandemic? Am J Clin Nutr 103:1033–1044. https://doi.org/10.3945/ajcn.115.120873
Article CAS PubMed PubMed Central Google Scholar
Traber MG (2014) Vitamin E inadequacy in humans: causes and consequences. Adv Nutr 5:503–514. https://doi.org/10.3945/an.114.006254
Article CAS PubMed PubMed Central Google Scholar
Pravst I, Lavrisa Z, Hribar M, Hristov H, Kvarantan N, Seljak BK, Gregoric M, Blaznik U, Gregoric N, Zaletel K, Oblak A, Osredkar J, Zmitek K, Kusar A (2021) Dietary intake of folate and assessment of the folate deficiency prevalence in Slovenia using serum biomarkers. Nutrients 13. https://doi.org/10.3390/nu13113860
Cuffe K, Stauffer W, Painter J, Shetty S, Montour J, Zhou W, Centers for Disease C, Prevention (2014) Update: vitamin B12 deficiency among Bhutanese refugees resettling in the united States, 2012. MMWR Morb Mortal Wkly Rep 63:607
PubMed PubMed Central Google Scholar
Mokhtari E, Mirzaei S, Asadi A, Akhlaghi M, Saneei P (2022) Association between plant-based diets and metabolic health status in adolescents with overweight and obesity. Sci Rep 12:13772. https://doi.org/10.1038/s41598-022-17969-4
Article CAS PubMed PubMed Central Google Scholar
Li X, Zhao Y, Zhang D, Kuang L, Huang H, Chen W, Fu X, Wu Y, Li T, Zhang J, Yuan L, Hu H, Liu Y, Zhang M, Hu F, Sun X, Hu D (2023) Development of an interpretable machine learning model associated with heavy metals’ exposure to identify coronary heart disease among US adults via SHAP: findings of the US NHANES from 2003 to 2018. Chemosphere 311:137039. https://doi.org/10.1016/j.chemosphere.2022.137039
Article CAS PubMed Google Scholar
Tao C, Fan Y, Niu R, Li Z, Qian H, Yu H, Xu Q, Xu Q, Lu C (2021) Urinary polycyclic aromatic hydrocarbons and sex hormones in children and adolescents: evidence from NHANES. Ecotoxicol Environ Saf 216:112215. https://doi.org/10.1016/j.ecoenv.2021.112215
Article CAS PubMed Google Scholar
Zhao H, Gui W, Liu S, Zhao F, Fan W, Jing F, Sun C (2024) Ultra-processed foods intake and sex hormone levels among children and adolescents aged 6–19 years: a cross-sectional study. Front Nutr 11:1451481. https://doi.org/10.3389/fnut.2024.1451481
Article CAS PubMed PubMed Central Google Scholar
Team TRC (2025) R: A Language and Environment for Statistical Computing. Available from: https://cran.r-project.org/doc/manuals/r-release/fullrefman.pdf
Package ‘tableone’ (2025). Available from: https://ccran.r-project.org/web/packages/tableone/tableone.pdf
Package ‘survey’ (2025). Available from: https://ccran.r-project.org/web/packages/survey/survey.pdf
Liu Q, Peng X, Gu Y, Shang X, Zhou Y, Zhang H, Zuo L, Mei G, Xiong C, Li H, Kong X (2021) Associations between smoking, sex hormone levels and late-onset hypogonadism in men differ depending on age. Aging 13:5226–5237. https://doi.org/10.18632/aging.202442
Article CAS PubMed PubMed Central Google Scholar
Package ‘bkmr’ (2025). Available from: https://ccran.r-project.org/web//packages/bkmr/bkmr.pdf
Zhang L, Xu Y, Li X, Yang F, Wang C, Yu C (2024) Multivitamin consumption and childhood asthma: a cross-sectional study of the NHANES database. BMC Pediatr 24:84. https://doi.org/10.1186/s12887-024-04540-5
Article CAS PubMed PubMed Central Google Scholar
Kihal A, Rodriguez-Prado M, Godoy C, Cristofol C, Calsamiglia S (2020) In vitro assessment of the capacity of certain Mycotoxin binders to adsorb some amino acids and water-soluble vitamins. J Dairy Sci 103:3125–3132. https://doi.org/10.3168/jds.2019-17561
Article CAS PubMed Google Scholar
Sobczynska-Malefora A, Harrington DJ (2018) Laboratory assessment of folate (vitamin B(9)) status. J Clin Pathol 71:949–956. https://doi.org/10.1136/jclinpath-2018-205048
Article CAS PubMed Google Scholar
Shulpekova Y, Nechaev V, Kardasheva S, Sedova A, Kurbatova A, Bueverova E, Kopylov A, Malsagova K, Dlamini JC, Ivashkin V (2021) The concept of folic acid in health and disease. Molecules 26. https://doi.org/10.3390/molecules26123731
Ly L, Chan D, Aarabi M, Landry M, Behan NA, MacFarlane AJ, Trasler J (2017) Intergenerational impact of paternal lifetime exposures to both folic acid deficiency and supplementation on reproductive outcomes and imprinted gene methylation. Mol Hum Reprod 23:461–477. https://doi.org/10.1093/molehr/gax029
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