Brain Abscess Treatment Followed by Sinonasal Mucormycosis—Report of Three Cases

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Background Brain abscess following sinonasal mucormycosis is a rare and life-threatening complication. Since our knowledge is mostly based on case reports, a well-documented way of treatment for such cases is yet to be found.

Case Description A retrospective case series study was conducted at a tertiary hospital. Patients whose brain abscesses were treated without opening the dura during surgery were selected for the study. The patients received radical debridement of necrotic tissues as well as the infected bones adjacent to the brain abscess. Then, they were treated medically. Three patients were included in the study. All patients had a history of diabetes and COVID-19 before developing symptoms of sinonasal infection. The average size of the abscesses was less than 2 cm.

Conclusion Removing infected tissues and bones surrounding the brain abscess without opening the dura can be a viable treatment option for mucormycosis-induced brain abscesses of less than 2 cm.

Keywords sinus - COVID-19 - mucormycosis - brain abscess Publication History

Received: 15 December 2025

Accepted after revision: 24 February 2026

Article published online:
11 June 2026

© 2026. The Author(s). This is an open access article published by Thieme under the terms of the Creative Commons Attribution-NonDerivative-NonCommercial-License, permitting copying and reproduction so long as the original work is given appropriate credit. Contents may not be used for commercial purposes, or adapted, remixed, transformed or built upon. (https://creativecommons.org/licenses/by-nc-nd/4.0/).

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