Hofman MS, Lawrentschuk N, Francis RJ, Tang C, Vela I, Thomas P, et al. Prostate-specific membrane antigen PET-CT in patients with high-risk prostate cancer before curative-intent surgery or radiotherapy (proPSMA): a prospective, randomised, multicentre study. Lancet. 2020;395:1208–16. https://doi.org/10.1016/S0140-6736(20)30314-7.
Article CAS PubMed Google Scholar
Cornford P, Tilki D, Van Den Bergh RCN, Eberli D, De Meerleer G, De Santis M, et al. EAU - EANM - ESTRO - ESUR - ISUP - SIOG Guidelines on Prostate Cancer. 2026. https://uroweb.org/guidelines/prostate-cancer/related-content.
Maurer T, Gschwend JE, Rauscher I, Souvatzoglou M, Haller B, Weirich G, et al. Diagnostic Efficacy of (68)Gallium-PSMA Positron Emission Tomography Compared to Conventional Imaging for Lymph Node Staging of 130 Consecutive Patients with Intermediate to High Risk Prostate Cancer. J Urol. 2016;195:1436–43. https://doi.org/10.1016/j.juro.2015.12.025.
Corfield J, Perera M, Bolton D, Lawrentschuk N. 68Ga-prostate specific membrane antigen (PSMA) positron emission tomography (PET) for primary staging of high-risk prostate cancer: a systematic review. World J Urol. 2018;36:519–27. https://doi.org/10.1007/s00345-018-2182-1.
Koerber SA, Utzinger MT, Kratochwil C, Kesch C, Haefner MF, Katayama S, et al. 68Ga-PSMA-11 PET/CT in Newly Diagnosed Carcinoma of the Prostate: Correlation of Intraprostatic PSMA Uptake with Several Clinical Parameters. J Nucl Med. 2017;58:1943–8. https://doi.org/10.2967/jnumed.117.190314.
Article CAS PubMed Google Scholar
Scheltema MJ, Chang JI, Stricker PD, van Leeuwen PJ, Nguyen QA, Ho B, et al. Diagnostic accuracy of 68Ga-prostate-specific membrane antigen (PSMA) positron-emission tomography (PET) and multiparametric (mp)MRI to detect intermediate-grade intra-prostatic prostate cancer using whole-mount pathology: impact of the addition of 68Ga-PSMA PET to mpMRI. BJU Int. 2019;124:42–9. https://doi.org/10.1111/bju.14794.
Article CAS PubMed Google Scholar
Pepe P, Pepe L, Tamburo M, Marletta G, Savoca F, Pennisi M, et al. 68Ga-PSMA PET/CT and Prostate Cancer Diagnosis: Which SUVmax Value?. Vivo. 2023;37:1318–22. https://doi.org/10.21873/invivo.13211.
Yi N, Wang Y, Zang S, Yang L, Liu H, Sun H, et al. Ability of 68Ga-PSMA PET/CT SUVmax to differentiate ISUP GG2 from GG3 in intermediate-risk prostate cancer: A single-center retrospective study of 147 patients. Cancer Med. 2023;12:7140–8. https://doi.org/10.1002/cam4.5516.
Article CAS PubMed Google Scholar
Jiao J, Kang F, Zhang J, Quan Z, Wen W, Zhao X, et al. Establishment and prospective validation of an SUVmax cutoff value to discriminate clinically significant prostate cancer from benign prostate diseases in patients with suspected prostate cancer by 68Ga-PSMA PET/CT: a real-world study. Theranostics. 2021;11:8396–411. https://doi.org/10.7150/thno.58140.
Article CAS PubMed PubMed Central Google Scholar
Roberts MJ, Papa N, Veerman H, de Bie K, Morton A, Franklin A, et al. Prediction of biochemical recurrence after radical prostatectomy from primary tumour characteristics. BJU Int. 2024;134:47–55. https://doi.org/10.1111/bju.16482.
Article CAS PubMed PubMed Central Google Scholar
Raveenthiran S, Yaxley WJ, Franklin T, Coughlin G, Roberts M, Gianduzzo T, et al. Findings in 1,123 Men with Preoperative 68Ga-Prostate-Specific Membrane Antigen Positron Emission Tomography/Computerized Tomography and Multiparametric Magnetic Resonance Imaging Compared to Totally Embedded Radical Prostatectomy Histopathology: Implications for the Diagnosis and Management of Prostate Cancer. J Urol. 2022;207:573–80. https://doi.org/10.1097/JU.0000000000002293.
Article CAS PubMed Google Scholar
Roberts MJ, Morton A, Papa N, Franklin A, Raveenthiran S, Yaxley WJ, et al. Primary tumour PSMA intensity is an independent prognostic biomarker for biochemical recurrence-free survival following radical prostatectomy. Eur J Nucl Med Mol Imaging. 2022;49:3289–94. https://doi.org/10.1007/s00259-022-05756-2.
Article CAS PubMed PubMed Central Google Scholar
Roberts MJ, Maurer T, Perera M, Eiber M, Hope TA, Ost P, et al. Using PSMA imaging for prognostication in localized and advanced prostate cancer. Nat Rev Urol. 2023;20:23–47. https://doi.org/10.1038/s41585-022-00670-6.
Chen DC, Huang S, Papa N, Siva S, Bolton DM, Lawrentschuk N, et al. Impact of intraprostatic PSMA maximum standardised uptake value following prostatectomy: a systematic review and meta-analysis. BJU Int. 2025;135:720–32. https://doi.org/10.1111/bju.16608.
Article CAS PubMed Google Scholar
Budäus L, Isbarn H, Schlomm T, Heinzer H, Haese A, Steuber T, et al. Current Technique of Open Intrafascial Nerve-Sparing Retropubic Prostatectomy. Eur Urol. 2009;56:317–24. https://doi.org/10.1016/j.eururo.2009.05.044.
Michl U, Tennstedt P, Feldmeier L, Mandel P, Oh SJ, Ahyai S, et al. Nerve-sparing Surgery Technique, Not the Preservation of the Neurovascular Bundles, Leads to Improved Long-term Continence Rates After Radical Prostatectomy. Eur Urol. 2016;69:584–9. https://doi.org/10.1016/j.eururo.2015.07.037.
R: The R Project for Statistical Computing. 2024. https://www.r-project.org/.
Kuten J, Fahoum I, Savin Z, Shamni O, Gitstein G, Hershkovitz D, et al. Head-to-Head Comparison of 68Ga-PSMA-11 with 18F-PSMA-1007 PET/CT in Staging Prostate Cancer Using Histopathology and Immunohistochemical Analysis as a Reference Standard. J Nucl Med. 2020;61:527–32. https://doi.org/10.2967/jnumed.119.234187.
Article CAS PubMed Google Scholar
Demirci E, Kabasakal L, Şahin OE, Akgün E, Gültekin MH, Doğanca T, et al. Can SUVmax values of Ga-68-PSMA PET/CT scan predict the clinically significant prostate cancer? Nucl Med Commun. 2019;40:86–91. https://doi.org/10.1097/MNM.0000000000000942.
Article PubMed PubMed Central Google Scholar
De Bie KCC, Veerman H, Bodar YJL, Meijer D, Van Leeuwen PJ, Van Der Poel HG, et al. Higher Preoperative Maximum Standardised Uptake Values (SUVmax) Are Associated with Higher Biochemical Recurrence Rates after Robot-Assisted Radical Prostatectomy for [68Ga]Ga-PSMA-11 and [18F]DCFPyL Positron Emission Tomography/Computed Tomography. Diagnostics. 2023;13:2343. https://doi.org/10.3390/diagnostics13142343.
Article CAS PubMed PubMed Central Google Scholar
Qiu X, Chen M, Yin H, Zhang Q, Li H, Guo S, et al. Prediction of Biochemical Recurrence After Radical Prostatectomy Based on Preoperative 68Ga-PSMA-11 PET/CT. Front Oncol. 2021;11:745530. https://doi.org/10.3389/fonc.2021.745530.
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