Modulation of Pharyngoesophageal Motility Characteristics During Concurrent Oral Feeding in Infants: Novel Pilot Observations

Hasenstab KA, Jadcherla SR. Evidence-based approaches to successful oral feeding in infants with feeding difficulties. Clin Perinatol. 2022;49:503–20.

Article  PubMed  Google Scholar 

Lau C. Development of infant oral feeding skills: what do we know? Am J Clin Nutr. 2016;103:S616–21.

Article  Google Scholar 

Hawdon JM, Beauregard N, Slattery J, Kennedy G. Identification of neonates at risk of developing feeding problems in infancy. Dev Med Child Neurol. 2007;42:235–9.

Article  Google Scholar 

Sultana Z, Hasenstab KA, Jadcherla SR. Pharyngoesophageal motility reflex mechanisms in the human neonate: importance of integrative cross-systems physiology. Am J Physiology-Gastrointestinal Liver Physiol. 2021;321:G139–48.

Article  CAS  Google Scholar 

Jadcherla SR, Wang M, Vijayapal AS, Leuthner SR. Impact of prematurity and co-morbidities on feeding milestones in neonates: A retrospective study. J Perinatol. 2010;30:201–8.

Article  CAS  PubMed  Google Scholar 

Viswanathan S, Jadcherla S. Feeding and swallowing difficulties in neonates: developmental physiology and pathophysiology. Clin Perinatol. 2020;47:223–41.

Article  PubMed  Google Scholar 

Lefton-Greif MA, Arvedson JC. Pediatric feeding and swallowing disorders: state of health, population trends, and application of the international classification of functioning, disability, and health. Semin Speech Lang. 2007;28:161–5.

Article  PubMed  Google Scholar 

Durvasula VS, O’Neill AC, Richter GT. Oropharyngeal dysphagia in children: mechanism, source, and management. Otolaryngol Clin North Am. 2014;47:691–720.

Article  PubMed  Google Scholar 

Pados BF, Hill RR, Yamasaki JT, Litt JS, Lee CS. Prevalence of problematic feeding in young children born prematurely: A meta-analysis. BMC Pediatr. 2021;21:110.

Article  PubMed  PubMed Central  Google Scholar 

Jadcherla SR. Challenges to eating, swallowing, and aerodigestive functions in infants: A burning platform that needs attention! J Pediatr. 2019;211:7–9.

Article  PubMed  Google Scholar 

Burklow KA, Phelps AN, Schultz JR, McConnell K, Rudolph C. Classifying complex pediatric feeding disorders. J Pediatr Gastroenterol Nutr. 1998;27:143–7.

CAS  PubMed  Google Scholar 

McGrattan KE, McGhee HC, McKelvey KL, Clemmens CS, Hill EG, DeToma A, Hill JG, Simmons CE, Martin-Harris B. Capturing infant swallow impairment on videofluoroscopy: timing matters. Pediatr Radiol. 2020;50:199–206.

Article  PubMed  Google Scholar 

Hogan AH, Bellin E, Douglas L, Levin TL, Esteban-Cruciani N. Radiation exposure of premature infants beyond the perinatal period. Hosp Pediatr. 2018;8:672–8.

Article  PubMed  PubMed Central  Google Scholar 

Ko EJ, Sung IY, Choi KH, Kwon YG, Yoon J, Kim T. Radiation exposure during videofluoroscopic swallowing studies in young children. Int J Pediatr Otorhinolaryngol. 2019;121:1–5.

Article  PubMed  Google Scholar 

Icrp, Khong PL, Ringertz H, Donoghue V, Frush D, Rehani M, Appelgate K, Sanchez R. Icrp publication 121: radiological protection in paediatric diagnostic and interventional radiology. Ann ICRP. 2013;42:1–63.

Article  PubMed  Google Scholar 

Martin-Harris B, Brodsky MB, Michel Y, Castell DO, Schleicher M, Sandidge J, Maxwell R, Blair J. Mbs measurement tool for swallow impairment–mbsimp: Establishing a standard. Dysphagia. 2008;23:392–405.

Article  PubMed  PubMed Central  Google Scholar 

Thompson B, Lundine JP, Madhoun L, Hu H, Holliman-Wade D, Bates DG. Standardization of radiologic procedures for pediatric videofluoroscopic swallow studies: A service-based quality improvement initiative. Pediatr Qual Saf. 2018;3:e123.

Article  PubMed  PubMed Central  Google Scholar 

Martin-Harris B, Carson KA, Pinto JM, Lefton-Greif MA. Babyvfssimp(©) a novel measurement tool for videofluoroscopic assessment of swallowing impairment in bottle-fed babies: Establishing a standard. Dysphagia. 2020;35:90–8.

Article  PubMed  Google Scholar 

Reynolds J, Carroll S, Sturdivant C. Fiberoptic endoscopic evaluation of swallowing: A multidisciplinary alternative for assessment of infants with dysphagia in the neonatal intensive care unit. Adv Neonatal Care. 2016;16:37–43.

Article  PubMed  Google Scholar 

Jadcherla SR, Gupta A, Stoner E, Fernandez S, Shaker R. Pharyngeal swallowing: defining pharyngeal and upper esophageal sphincter relationships in human neonates. J Pediatr. 2007;151:597–603.

Article  PubMed  PubMed Central  Google Scholar 

Jadcherla SR, Shubert TR, Gulati IK, Jensen PS, Wei L, Shaker R. Upper and lower esophageal sphincter kinetics are modified during maturation: effect of pharyngeal stimulus in premature infants. Pediatr Res. 2015;77:99–106.

Article  PubMed  Google Scholar 

Jadcherla SR, Prabhakar V, Hasenstab KA, Nawaz S, Das J, Kern M, Balasubramanian G, Shaker R. Defining pharyngeal contractile integral during high-resolution manometry in neonates: A neuromotor marker of pharyngeal Vigor. Pediatr Res. 2018;84:341–7.

Article  PubMed  PubMed Central  Google Scholar 

Prabhakar V, Hasenstab KA, Osborn E, Wei L, Jadcherla SR. Pharyngeal contractile and regulatory characteristics are distinct during nutritive oral stimulus in preterm-born infants: implications for clinical and research applications. Neurogastroenterol Motil. 2019;31:e13650.

Article  PubMed  PubMed Central  Google Scholar 

Rommel N, van Wijk M, Boets B, Hebbard G, Haslam R, Davidson G, Omari T. Development of pharyngo-esophageal physiology during swallowing in the preterm infant. Neurogastroenterol Motil. 2011;23:e401–408.

Article  CAS  PubMed  Google Scholar 

Pados BF. Milk flow rates from bottle nipples: what we know and why it matters. Nurs Womens Health. 2021;25:229–35.

Article  PubMed  Google Scholar 

Mathew OP. Breathing patterns of preterm infants during bottle feeding: role of milk flow. J Pediatr. 1991;119:960–5.

Article  CAS  PubMed  Google Scholar 

Moroishi Y, Signes-Pastor AJ, Li Z, Cottingham KL, Jackson BP, Punshon T, Madan J, Nadeau K, Gui J, Karagas MR. Infant infections, respiratory symptoms, and allergy in relation to timing of rice cereal introduction in a united States cohort. Sci Rep. 2022;12:4450.

Article  CAS  PubMed  PubMed Central  Google Scholar 

Madhoun LL, Siler-Wurst KK, Sitaram S, Jadcherla SR. Feed-thickening practices in nicus in the current era: variability in prescription and implementation patterns. J Neonatal Nurs. 2015;21:255–62.

Article  PubMed  PubMed Central  Google Scholar 

Orenstein SR, Magill HL, Brooks P. Thickening of infant feedings for therapy of gastroesophageal reflux. J Pediatr. 1987;110:181–6.

Article  CAS  PubMed  Google Scholar 

Mascarenhas R, Landry L, Khoshoo V. Difficulty in defecation in infants with gastroesophageal reflux treated with smaller volume feeds thickened with rice cereal. Clin Pediatr (Phila). 2005;44:671–3.

Article  PubMed  Google Scholar 

Regan FM, Cutfield WS, Jefferies C, Robinson E, Hofman PL. The impact of early nutrition in premature infants on later childhood insulin sensitivity and growth. Pediatrics. 2006;118:1943–9.

Article  PubMed  Google Scholar 

Horvath A, Dziechciarz P, Szajewska H. The effect of thickened-feed interventions on gastroesophageal reflux in infants: systematic review and meta-analysis of randomized, controlled trials. Pediatrics. 2008;122:e1268–1277.

Article  PubMed  Google Scholar 

Lau C. To individualize the management care of high-risk infants with oral feeding challenges: what do we know? what can we do? Front Pediatr. 2020;8:296.

Article  PubMed  PubMed Central  Google Scholar 

McGrattan KE, Sivalingam M, Hasenstab KA, Wei L, Jadcherla SR. The physiologic coupling of sucking and swallowing coordination provides a unique process for neonatal survival

Comments (0)

No login
gif