Current evidence and strategies for preventing tumor recurrence following thermal ablation of papillary thyroid carcinoma

Chen DW, Lang B, McLeod D, Newbold K, Haymart MR. Thyroid cancer. Lancet. 2023;401(10387):1531–44.

PubMed  Google Scholar 

Kim MJ, Moon JH, Lee EK, Song YS, Jung KY, Lee JY, et al. Active surveillance for Low-Risk thyroid cancers: A review of current practice guidelines. Endocrinol Metab (Seoul). 2024;39(1):47–60.

PubMed  Google Scholar 

Pace-Asciak P, Russell JO, Tufano RP. Surgical treatment of thyroid cancer: established and novel approaches. Best Pract Res Clin Endocrinol Metab. 2023;37(1):101664.

PubMed  Google Scholar 

Mauri G, Hegedüs L, Bandula S, Cazzato RL, Czarniecka A, Dudeck O, et al. European thyroid association and cardiovascular and interventional radiological society of Europe 2021 clinical practice guideline for the use of minimally invasive treatments in malignant thyroid lesions. Eur Thyroid J. 2021;10(3):185–97.

PubMed  PubMed Central  Google Scholar 

China Association of Head and Neck Oncology, et al. Guidelines for the diagnosis and management of thyroid nodules and differentiated thyroid cancer (Second edition). Chin J Endocrinol Metab. 2023;39(3):181–226.

Google Scholar 

Orloff LA, Noel JE, Stack BC Jr, Russell MD, Angelos P, Baek JH, et al. Radiofrequency ablation and related ultrasound-guided ablation technologies for treatment of benign and malignant thyroid disease: an international multidisciplinary consensus statement of the American head and neck society endocrine surgery section with the Asia Pacific society of thyroid surgery, associazione Medici endocrinologi, British association of endocrine and thyroid surgeons, European thyroid association, Italian society of endocrine surgery units, Korean society of thyroid radiology, Latin American thyroid society, and thyroid nodules therapies association. Head Neck. 2022;44(3):633–60.

PubMed  Google Scholar 

Kuo CY, Tsai CH, Wu JK, Cheng SP. Sublethal thermal stress promotes migration and invasion of thyroid cancer cells. PLoS ONE. 2024;19(2):e0298903.

CAS  PubMed  PubMed Central  Google Scholar 

Han ZY, Dou JP, Zheng L, Che Y, Yu MA, Wang SR, et al. Safety and efficacy of microwave ablation for the treatment of low-risk papillary thyroid microcarcinoma: a prospective multicenter study. Eur Radiol. 2023;33(11):7942–51.

PubMed  Google Scholar 

Yan L, Zhang M, Song Q, Luo Y. Ultrasound-Guided radiofrequency ablation versus thyroid lobectomy for Low-Risk papillary thyroid microcarcinoma: A Propensity-Matched cohort study of 884 patients. Thyroid. 2021;31(11):1662–72.

CAS  PubMed  Google Scholar 

van Dijk S, Coerts HI, Gunput S, van Velsen E, Medici M, Moelker A, et al. Assessment of radiofrequency ablation for papillary microcarcinoma of the thyroid: A systematic review and Meta-analysis. JAMA Otolaryngol Head Neck Surg. 2022;148(4):317–25.

PubMed  PubMed Central  Google Scholar 

Jeong SY, Baek SM, Shin S, Son JM, Kim H, Baek JH. Radiofrequency ablation of Low-Risk papillary thyroid microcarcinoma: A retrospective cohort study including patients with more than 10 years of Follow-up. Thyroid. 2025;35(2):143–52.

PubMed  Google Scholar 

Li X, Yan L, Xiao J, Li Y, Yang Z, Zhang M, et al. Long-Term outcomes and risk factors of radiofrequency ablation for T1N0M0 papillary thyroid carcinoma. JAMA Surg. 2024;159(1):51–8.

PubMed  Google Scholar 

Yan L, Yang Z, Jing H, Xiao J, Li Y, Li X, et al. Comparative outcomes of ultrasound-guided radiofrequency ablation vs. microwave ablation for patients with T1N0M0 papillary thyroid carcinoma: a retrospective cohort study. Eur Radiol. 2025;35(7):3697–706.

CAS  PubMed  Google Scholar 

Yan L, Li Y, Li X, Xiao J, Jing H, Yang Z, et al. Thermal ablation for papillary thyroid carcinoma. JAMA Otolaryngol Head Neck Surg. 2024;151(1):9–17.

PubMed  Google Scholar 

Fei YL, Wei Y, Zhao ZL, Peng LL, Li Y, Cao SL, et al. Efficacy and safety of thermal ablation for solitary Low-Risk T2N0M0 papillary thyroid carcinoma. Korean J Radiol. 2024;25(8):756–66.

PubMed  PubMed Central  Google Scholar 

Li X, Li Y, Yan L, Xiao J, Yang Z, Jing H, et al. Sonographic evolution and pathologic findings of papillary thyroid Cancer after radiofrequency ablation: A Five-Year retrospective cohort study. Thyroid. 2024;34(1):54–63.

CAS  PubMed  Google Scholar 

Ma B, Wei W, Xu W, Wang Y, Guan H, Fan J, et al. Surgical confirmation of incomplete treatment for primary papillary thyroid carcinoma by percutaneous thermal ablation: A retrospective case review and literature review. Thyroid. 2018;28(9):1134–42.

PubMed  Google Scholar 

Ding M, Wu GS, Gu JH, Shen DJ, Zhou R, Liu Y, et al. Pathology confirmation of the efficacy and safety of microwave ablation in papillary thyroid carcinoma. Front Endocrinol (Lausanne). 2022;13:929651.

PubMed  PubMed Central  Google Scholar 

Miyauchi A, Ito Y, Fujishima M, Miya A, Onoda N, Kihara M, et al. Long-Term outcomes of active surveillance and immediate surgery for adult patients with Low-Risk papillary thyroid microcarcinoma: 30-Year experience. Thyroid. 2023;33(7):817–25.

PubMed  PubMed Central  Google Scholar 

Jin L, Zhu K, Xu C, Lu J, Huang L. Incidence and risk factors for occult lesions in low-risk papillary thyroid microcarcinoma patients with tumor characteristics appropriate for thermal ablation: A retrospective study. Med (Baltim). 2023;102(38):e34938.

CAS  Google Scholar 

Sun W, Zhang H, He L, Zhang T, Wang Z, Dong W, et al. Surgery after Ultrasound-Guided radiofrequency ablation for papillary thyroid carcinoma in 21 patients: A retrospective study from a single center in China. Med Sci Monit. 2020;26:e928391.

PubMed  PubMed Central  Google Scholar 

Qiu P, Guo Q, Pan K, Lin J. Development of a nomogram for prediction of central lymph node metastasis of papillary thyroid microcarcinoma. BMC Cancer. 2024;24(1):235.

PubMed  PubMed Central  Google Scholar 

Sun J, Jiang Q, Wang X, Liu W, Wang X. Nomogram for preoperative Estimation of cervical lymph node metastasis risk in papillary thyroid microcarcinoma. Front Endocrinol (Lausanne). 2021;12:613974.

PubMed  Google Scholar 

Liu LS, Liang J, Li JH, Liu X, Jiang L, Long JX, et al. The incidence and risk factors for central lymph node metastasis in cN0 papillary thyroid microcarcinoma: a meta-analysis. Eur Arch Otorhinolaryngol. 2017;274(3):1327–38.

PubMed  Google Scholar 

Liu C, Xiao C, Chen J, Li X, Feng Z, Gao Q, et al. Risk factor analysis for predicting cervical lymph node metastasis in papillary thyroid carcinoma: a study of 966 patients. BMC Cancer. 2019;19(1):622.

PubMed  PubMed Central  Google Scholar 

Suh CH, Baek JH, Choi YJ, Lee JH. Performance of CT in the preoperative diagnosis of cervical lymph node metastasis in patients with papillary thyroid cancer: A systematic review and Meta-Analysis. AJNR Am J Neuroradiol. 2017;38(1):154–61.

CAS  PubMed  PubMed Central  Google Scholar 

CSJ, SCH, BJH, CSR, CYJ, LJH. Diagnostic performance of MRI to detect metastatic cervical lymph nodes in patients with thyroid cancer: a systematic review and meta-analysis. Clin Radiol. 2020;75(7):e5621–56210.

Albuck AL, Issa PP, Hussein M, Aboueisha M, Attia AS, Omar M, et al. A combination of computed tomography scan and ultrasound provides optimal detection of cervical lymph node metastasis in papillary thyroid carcinomas: A systematic review and meta-analysis. Head Neck. 2023;45(9):2173–84.

PubMed  Google Scholar 

Ren Y, Lu C, Xu S. Ultrasound-guided thermal ablation for papillary thyroid microcarcinoma: the devil is in the details. Int J Hyperth. 2023;40(1):2278823.

Google Scholar 

Zhang Y, Lu YY, Li W, Zhao JH, Zhang Y, He HY, et al. Lymphatic Contrast-enhanced US to improve the diagnosis of cervical lymph node metastasis from thyroid Cancer. Radiology. 2023;307(4):e221265.

PubMed  Google Scholar 

Fu J, Liu J, Wang Z, Qian L. Predictive values of clinical features and multimodal ultrasound for central lymph node metastases in papillary thyroid carcinoma. Diagnostics (Basel). 2024;14(16):1770.

CAS  PubMed  PubMed Central  Google Scholar 

Wang B, Cao Q, Cui XW, Dietrich CF, Yi AJ. A model based on clinical data and multi-modal ultrasound for predicting cervical lymph node metastasis in patients with thyroid papillary carcinoma. Front Endocrinol (Lausanne). 2022;13:1063998.

PubMed  Google Scholar 

Fnais N, Soobiah C, Al-Qahtani K, Hamid JS, Perrier L, Straus SE, et al. Diagnostic value of fine needle aspiration BRAF(V600E) mutation analysis in papillary thyroid cancer: a systematic review and meta-analysis. Hum Pathol. 2015;46(10):1443–54.

CAS  PubMed  Google Scholar 

Song JY, Sun SR, Dong F, Huang T, Wu B, Zhou J. Predictive value of BRAF(V600E) mutation for lymph node metastasis in papillary thyroid cancer: A Meta-analysis. Curr Med Sci. 2018;38(5):785–97.

CAS  PubMed  Google Scholar 

Enumah S, Fingeret A, Parangi S, Dias-Santagata D, Sadow PM, Lubitz CC. BRAF(V600E) mutation is associated with an increased risk of papillary thyroid Cancer recurrence. World J Surg. 2020;44(8):2685–91.

PubMed  PubMed Central  Google Scholar 

Damiani L, Lupo S, Rossi R, Bruni S, Bartolomei M, Panareo S, et al. Evaluation of the role of BRAFV600E somatic mutation on papillary thyroid Cancer disease persistence: A prospective study. Eur Thyroid J. 2018;7(5):251–7.

CAS  PubMed  PubMed Central  Google Scholar 

Dong SY, Zeng RC, Jin LP, Yang F, Zhang XJ, Yao ZH, et al. BRAF(V600E) mutation is not associated with central lymph node metastasis in all patients with papillary thyroid cancer: different histological subtypes and preoperative lymph node status should be taken into account. Oncol Lett. 2017;14(4):4122–34.

PubMed  PubMed Central  Google Scholar 

Kakarmath S, Heller HT, Alexander CA, Cibas ES, Krane JF, Barletta JA, et al. Clinical, sonographic, and pathological characteristics of RAS-Positive versus BRAF-Positive thyroid carcinoma. J Clin Endocrinol Metab. 2016;101(12):4938–44.

CAS  PubMed  PubMed Central  Google Scholar 

Staubit

Comments (0)

No login
gif