Hypoplastic Left Heart Syndrome in U.S. Children: A 20-Year Look at Lives Lost and Gaps That Remain

Grossfeld P, Nie S, Lin L, Wang L, Anderson RH (2019) Hypoplastic left heart syndrome: a new paradigm for an old disease? J Cardiovasc Dev Dis 6:10

PubMed  PubMed Central  CAS  Google Scholar 

Barron DJ, Kilby MD, Davies B, Wright JG, Jones TJ, Brawn WJ (2009) Hypoplastic left heart syndrome. Lancet 374:551–564

PubMed  Google Scholar 

Feinstein JA, Benson DW, Dubin AM et al (2012) Hypoplastic left heart syndrome. J Am Coll Cardiol 59:S1–S42

PubMed  PubMed Central  Google Scholar 

Goldberg CS, Mussatto K, Licht D, Wernovsky G (2011) Neurodevelopment and quality of life for children with hypoplastic left heart syndrome: current knowns and unknowns. Cardiol Young 21:88–92

PubMed  Google Scholar 

Best KE, Miller N, Draper E, Tucker D, Luyt K, Rankin J (2021) The improved prognosis of hypoplastic left heart: a population-based register study of 343 cases in England and Wales. Front Pediatr. https://doi.org/10.3389/fped.2021.635776

Article  PubMed  PubMed Central  Google Scholar 

Aggarwal R, Chiu N, Loccoh EC, Kazi DS, Yeh RW, Wadhera RK (2021) Rural-urban disparities: diabetes, hypertension, heart disease, and stroke mortality among black and white adults, 1999–2018. J Am Coll Cardiol 77:1480–1481

PubMed  PubMed Central  Google Scholar 

Ingram DD, Franco SJ (2013) NCHS urban-rural classification scheme for counties. Vital Health Stat 2(2014):1–73

Google Scholar 

Hehir DA, Rudd N, Slicker J et al (2012) Normal interstage growth after the Norwood operation associated with interstage home monitoring. Pediatr Cardiol 33:1315–1322

PubMed  PubMed Central  Google Scholar 

Stasik CN, Gelehrter S, Goldberg CS, Bove EL, Devaney EJ, Ohye RG. Current outcomes and risk factors for the Norwood procedure [published correction appears in J Thorac Cardiovasc Surg. 2007 Mar;133(3):602. Gelehrter, S [added]]. J Thorac Cardiovasc Surg. 2006;131(2):412-417. https://doi.org/10.1016/j.jtcvs.2005.09.030

Czosek RJ, Anderson JB, Heaton PC, Cassedy A, Schnell B, Cnota JF (2013) Staged palliation of hypoplastic left heart syndrome: trends in mortality, cost, and length of stay using a national database from 2000 through 2009. Am J Cardiol 111:1792–1799

PubMed  Google Scholar 

Urencio M, Greenleaf C, Salazar JD, Dodge-Khatami A (2016) Resource and cost considerations in treating hypoplastic left heart syndrome. Pediatr Health Med Ther 7:149–153. https://doi.org/10.2147/PHMT.S98327

Article  Google Scholar 

Bezuska L, O’Doherty JP, Ali B, Harvey C, Omeje I, Mimic B (2023) Extracorporeal membrane oxygenation in paediatric cardiac surgery: 5-year single centre experience. J Cardiothorac Surg 18(1):314. https://doi.org/10.1186/s13019-023-02440-w

Article  PubMed  PubMed Central  Google Scholar 

Bezerra RF, Pacheco JT, Volpatto VH et al (2022) Extracorporeal membrane oxygenation after Norwood surgery in patients with hypoplastic left heart syndrome: a retrospective single-center cohort study from Brazil. Front Pediatr 10:813528. https://doi.org/10.3389/fped.2022.813528

Article  PubMed  PubMed Central  Google Scholar 

Cho HJ, Choi I, Kwak Y, Kim DW, Habimana R, Jeong IS (2022) The outcome of post-cardiotomy extracorporeal membrane oxygenation in neonates and pediatric patients: a systematic review and meta-analysis. Front Pediatr 10:869283. https://doi.org/10.3389/fped.2022.869283

Article  PubMed  PubMed Central  Google Scholar 

Tworetzky W, McElhinney DB, Reddy VM, Brook MM, Hanley FL, Silverman NH (2001) Improved surgical outcome after fetal diagnosis of hypoplastic left heart syndrome. Circulation 103:1269–1273

PubMed  CAS  Google Scholar 

Anderson JB et al (2015) Improvement in interstage survival in a national pediatric cardiology learning network. Circ Cardiovasc Qual Outcomes 8(4):428–436. https://doi.org/10.1161/CIRCOUTCOMES.115.001956

Article  PubMed  Google Scholar 

Dean PN, McHugh KE, Conaway MR, Hillman DG, Gutgesell HP (2013) Effects of race, ethnicity, and gender on surgical mortality in Hypoplastic Left Heart Syndrome. Pediatr Cardiol 34:1829–1836

PubMed  PubMed Central  Google Scholar 

Pugnaloni F, Felici A, Corno AF, Marino B, Versacci P, Putotto C (2023) Gender differences in congenital heart defects: a narrative review. Transl Pediatr 12(9):1753–1764. https://doi.org/10.21037/tp-23-260

Article  PubMed  PubMed Central  Google Scholar 

Chang R-KR, Chen AY, Klitzner TS (2002) Female sex as a risk factor for in-hospital mortality among children undergoing cardiac surgery. Circulation 106:1514–1522

PubMed  Google Scholar 

Williamson CG, Tran Z, Rudasill S et al (2022) Race-based disparities in access to surgical palliation for hypoplastic left heart syndrome. Surgery 172:500–505

PubMed  Google Scholar 

Nembhard WN, Xu P, Ethen MK, Fixler DE, Salemi JL, Canfield MA (2013) Racial/ethnic disparities in timing of death during childhood among children with congenital heart defects. Birth Defects Res A Clin Mol Teratol 97:628–640

PubMed  CAS  Google Scholar 

Anderson JB, Beekman RH 3rd, Eghtesady P et al (2010) Predictors of poor weight gain in infants with a single ventricle. J Pediatr 157(3):407-413.e1. https://doi.org/10.1016/j.jpeds.2010.04.012

Article  PubMed  Google Scholar 

Anderson JB, Beekman RH 3rd, Border WL et al (2009) Lower weight-for-age z score adversely affects hospital length of stay after the bidirectional Glenn procedure in 100 infants with a single ventricle. J Thorac Cardiovasc Surg 138(2):397-404.e1. https://doi.org/10.1016/j.jtcvs.2009.02.033

Article  PubMed  Google Scholar 

Davtyan A, Ostler H, Golding IF, Sun HY (2024) Prenatal diagnosis rate of critical congenital heart disease remains inadequate with significant racial/ethnic and socioeconomic disparities and technical barriers. Pediatr Cardiol 45(8):1713–1723. https://doi.org/10.1007/s00246-023-03262-2

Article  PubMed  Google Scholar 

Frank LH, Glickstein J, Brown DW, Mink RB, Ross RD (2024) Child health needs and the pediatric cardiology workforce: 2020–2040. Pediatrics 153:e2023063678E

PubMed  Google Scholar 

Lyon SM, Douglas IS, Cooke CR (2014) Medicaid expansion under the Affordable Care Act. Implications for insurance-related disparities in pulmonary, critical care, and sleep. Ann Am Thorac Soc 11(4):661–667. https://doi.org/10.1513/AnnalsATS.201402-072PS

Article  PubMed  PubMed Central  Google Scholar 

Chowdhury D, Elliott PA, Asaki SY et al (2024) Addressing disparities in pediatric congenital heart disease: a call for equitable health care. J Am Heart Assoc 13(13):e032415. https://doi.org/10.1161/JAHA.123.032415

Article  PubMed  PubMed Central  Google Scholar 

Schillinger D (2021) Social determinants, health literacy, and disparities: intersections and controversies. HLRP Health Lit Res Pract 5(3):e234–e243. https://doi.org/10.3928/24748307-20210712-01

Article  PubMed  Google Scholar 

Basu S, Berkowitz SA, Phillips RL, Bitton A, Landon BE, Phillips RS (2019) Association of primary care physician supply with population mortality in the United States, 2005–2015. JAMA Intern Med 179:506

PubMed  PubMed Central  Google Scholar 

Rimsza ME, Ruch-Ross HS, Clemens CJ, Moskowitz WB, Mulvey HJ (2018) Workforce trends and analysis of selected pediatric subspecialties in the United States. Acad Pediatr 18:805–812

PubMed  Google Scholar 

Cushing AM, Bucholz EM, Chien AT, Rauch DA, Michelson KA (2021) Availability of pediatric inpatient services in the United States. Pediatrics 148(1):e2020041723. https://doi.org/10.1542/peds.2020-041723

Article  PubMed  Google Scholar 

McCarthy S, Moore D, Smedley WA et al (2021) Impact of rural hospital closures on health-care access. J Surg Res 258:170–178

PubMed  Google Scholar 

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