Al-Toma A, Volta U, Auricchio R, Castillejo G, Sanders DS, Cellier C et al (2019) European society for the study of Coeliac disease (ESsCD) guideline for coeliac disease and other gluten-related disorders. United Eur Gastroenterol J 7(5):583–613
Alam MS, Thomas L, Brumpton B, Hveem K, Lundin KEA, Withoff S et al (2025) Population screening of adults identifies novel genetic variants associated with Celiac disease. Sci Rep 15(1):19764
Article PubMed PubMed Central Google Scholar
Åsvold BO, Langhammer A, Rehn TA, Kjelvik G, Grøntvedt TV, Sørgjerd EP et al (2023) Cohort profile update: the HUNT study, Norway. Int J Epidemiol 52(1):e80–91
Dubois PCA, Trynka G, Franke L, Hunt KA, Romanos J, Curtotti A et al (2010) Multiple common variants for celiac disease influencing immune gene expression. Nat Genet 42(4):295–302
Article PubMed PubMed Central Google Scholar
Gutierrez-Achury J, Zhernakova A, Pulit SL, Trynka G, Hunt KA, Romanos J et al (2015) Fine mapping in the MHC region accounts for 18% additional genetic risk for Celiac disease. Nat Genet 47(6):577–578
Article PubMed PubMed Central Google Scholar
Hjort R, Andersen IL, Lukina P, Hveem K, Lundin KEA, Sollid LM et al (2024) Mapping of HLA-DQ haplotypes in adults with coeliac disease in a large, screened population—results from the HUNT study. Gastroenterology 166(5):S–728
Kang JY, Kang AHY, Green A, Gwee KA, Ho KY (2013) Systematic review: worldwide variation in the frequency of coeliac disease and changes over time. Aliment Pharmacol Ther 38(3):226–245
Klaasen RA, Warren DJ, Iversen R, Bolstad N, Andersen IL, Mjønes P et al (2022) The development and validation of a high-capacity serological assay for Celiac disease. Clin Biochem 107:13–18
Ludvigsson JF, Leffler DA, Bai JC, Biagi F, Fasano A, Green PHR et al (2013) The Oslo definitions for coeliac disease and related terms. Gut. Available from: https://gut.bmj.com/content/62/1/43?62/1/43r62/1/43
Lukina P, Andersen IL, Eggen PT, Mjønes PG, Rønne E, Bolstad N et al (2024) Coeliac disease in the Trøndelag health study (HUNT), norway, a population-based cohort of Coeliac disease patients. BMJ Open 14(1):e077131
Article PubMed PubMed Central Google Scholar
Lukina P, Andersen IL, Klaasen RA, Warren DJ, Bolstad N, Mjønes P et al (2024) The prevalence and rate of undiagnosed celiac disease in an adult general population, the Trøndelag Health Study, Norway. Clin Gastroenterol Hepatol. Available from: https://doi.org/10.1016/j.cgh.2024.06.027
Makharia GK, Chauhan A, Singh P, Ahuja V (2022) Review article: epidemiology of coeliac disease. Aliment Pharmacol Ther 56(Suppl 1):S3–17
McCarthy S, Das S, Kretzschmar W, Delaneau O, Wood AR, Teumer A et al (2016) A reference panel of 64,976 haplotypes for genotype imputation. Nat Genet 48(10):1279–1283
Article PubMed PubMed Central Google Scholar
Oberhuber G (2000) Histopathology of celiac disease. Biomed Pharmacother 54(7):368–372
Olano C (2021) A deep dive into the submerged ‘coeliac iceberg’. Nat Rev Gastroenterol Hepatol 18(11):748–748
Privé F, Aschard H, Carmi S, Folkersen L, Hoggart C, O’Reilly PF et al (2022) Portability of 245 polygenic scores when derived from the UK biobank and applied to 9 ancestry groups from the same cohort. Am J Hum Genet 109(1):12–23
Article PubMed PubMed Central Google Scholar
Purcell S, Neale B, Todd-Brown K, Thomas L, Ferreira MAR, Bender D et al (2007) PLINK: a tool set for whole-genome association and population-based linkage analyses. Am J Hum Genet 81(3):559–575
Article PubMed PubMed Central Google Scholar
R Core Team (2021) R: A Language and environment for statistical computing. R Foundation for Statistical Computing, Vienna
Ricaño-Ponce I, Gutierrez-Achury J, Costa AF, Deelen P, Kurilshikov A, Zorro MM et al (2020) Immunochip meta-analysis in European and Argentinian populations identifies two novel genetic loci associated with celiac disease. Eur J Hum Genet 28(3):313–323
Romanos J, Rosén A, Kumar V, Trynka G, Franke L, Szperl A et al (2014) Improving coeliac disease risk prediction by testing non-HLA variants additional to HLA variants. Gut 63(3):415–422
RStudio Team (2020) RStudio: integrated development environment for R. RStudio, PBC., Boston
Rubinacci S, Delaneau O, Marchini J (2020) Genotype imputation using the positional burrows wheeler transform. PLoS Genet 16(11):e1009049
Article PubMed PubMed Central Google Scholar
Schoeler T, Speed D, Porcu E, Pirastu N, Pingault JB, Kutalik Z (2023) Participation bias in the UK biobank distorts genetic associations and downstream analyses. Nat Hum Behav 7(7):1216–1227
Article PubMed PubMed Central Google Scholar
Singh P, Arora A, Strand TA, Leffler DA, Catassi C, Green PH et al (2018) Global prevalence of Celiac disease: systematic review and meta-analysis. Clin Gastroenterol Hepatol 16(6):823–836e2
Sollid LM (2017) The roles of MHC class II genes and post-translational modification in celiac disease. Immunogenetics 69(8–9):605–616
Stelzer G, Plaschkes I, Oz-Levi D, Alkelai A, Olender T, Zimmerman S et al (2016) VarElect: the phenotype-based variation prioritizer of the genecards suite. BMC Genomics 17(2):444
Article PubMed PubMed Central Google Scholar
Trynka G, Hunt KA, Bockett NA, Romanos J, Mistry V, Szperl A et al (2011) Dense genotyping identifies and localizes multiple common and rare variant association signals in celiac disease. Nat Genet 43(12):1193–1201
Article PubMed PubMed Central Google Scholar
van Heel DA, Franke L, Hunt KA, Gwilliam R, Zhernakova A, Inouye M et al (2007) A genome-wide association study for Celiac disease identifies risk variants in the region harboring IL2 and IL21. Nat Genet 39(7):827–829
Article PubMed PubMed Central Google Scholar
Wang K, Li M, Hakonarson H (2010) ANNOVAR: functional annotation of genetic variants from high-throughput sequencing data. Nucleic Acids Res 38(16):e164
Article PubMed PubMed Central Google Scholar
Zhou W, Nielsen JB, Fritsche LG, Dey R, Gabrielsen ME, Wolford BN et al (2018) Efficiently controlling for case-control imbalance and sample relatedness in large-scale genetic association studies. Nat Genet 50(9):1335–1341
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