Vaccarella S, Franceschi S, Bray F, Wild CP, Plummer M, Dal Maso L (2016) Worldwide thyroid-cancer epidemic? The increasing impact of overdiagnosis. N Engl J Med 375:614–617. https://doi.org/10.1056/NEJMp1604412

Article  PubMed  Google Scholar 

Sung H, Ferlay J, Siegel RL, Laversanne M, Soerjomataram I, Jemal A, Bray F (2021) Global cancer statistics 2020: GLOBOCAN estimates of incidence and mortality worldwide for 36 cancers in 185 countries. CA Cancer J Clin 71:209–249. https://doi.org/10.3322/caac.21660

Article  CAS  PubMed  Google Scholar 

Kitahara CM, Sosa JA (2016) The changing incidence of thyroid cancer. Nat Rev Endocrinol 12:646–653. https://doi.org/10.1038/nrendo.2016.110

Article  PubMed  PubMed Central  Google Scholar 

Cabanillas ME, McFadden DG, Durante C (2016) Thyroid cancer. Lancet 388:2783–2795. https://doi.org/10.1016/S0140-6736(16)30172-6

Article  CAS  PubMed  Google Scholar 

Makazlieva T, Vaskova O, Majstorov V (2016) Etiopathogenesis of differentiated thyroid carcinomas. Open Access Maced J Med Sci 4:517–522. https://doi.org/10.3889/oamjms.2016.086

Article  PubMed  PubMed Central  Google Scholar 

Prete A, Borges de Souza P, Censi S, Muzza M, Nucci N, Sponziello M (2020) Update on fundamental mechanisms of thyroid cancer. Front Endocrinol (Lausanne) 11:102. https://doi.org/10.3389/fendo.2020.00102

Article  PubMed  Google Scholar 

Katoh H, Yamashita K, Enomoto T, Watanabe M (2015) Classification and general considerations of thyroid cancer. Ann Clin Pathol

Biscolla RP, Ugolini C, Sculli M, Bottici V, Castagna MG, Romei C, Cosci B, Molinaro E, Faviana P, Basolo F, Miccoli P, Pacini F, Pinchera A, Elisei R (2004) Medullary and papillary tumors are frequently associated in the same thyroid gland without evidence of reciprocal influence in their biologic behavior. Thyroid 14:946–952. https://doi.org/10.1089/thy.2004.14.946

Article  PubMed  Google Scholar 

Rossi S, Fugazzola L, De Pasquale L, Braidotti P, Cirello V, Beck-Peccoz P, Bosari S, Bastagli A (2005) Medullary and papillary carcinoma of the thyroid gland occurring as a collision tumour: report of three cases with molecular analysis and review of the literature. Endocr Relat Cancer 12:281–289. https://doi.org/10.1677/erc.1.00901

Article  CAS  PubMed  Google Scholar 

Younes N, Shomaf M, Al Hassan L (2005) Simultaneous medullary and papillary thyroid carcinoma with lymph node metastasis in the same patient: case report and review of the literature. Asian J Surg 28:223–226. https://doi.org/10.1016/s1015-9584(09)60348-1

Article  PubMed  Google Scholar 

Adnan Z, Arad E, Dana J, Shendler Y, Baron E (2013) Simultaneous occurrence of medullary and papillary thyroid microcarcinomas: a case series and review of the literature. J Med Case Rep 7:26. https://doi.org/10.1186/1752-1947-7-26

Article  PubMed  PubMed Central  Google Scholar 

De Lellis R (2004) Tumours of endocrine organs. World Health Organization Classification of Tumours; Pathology and Genetics

Nangue C, Bron L, Portmann L, Volante M, Ris H-B, Monnier P, Andrejevic-Blant S (2009) Mixed medullary-papillary carcinoma of the thyroid: report of a case and review of the literature. Head Neck 31:968–974. https://doi.org/10.1002/hed.20984

Article  PubMed  Google Scholar 

Fagin JA, Wells SA (2016) Biologic and clinical perspectives on thyroid cancer. N Engl J Med 375:1054–1067. https://doi.org/10.1056/NEJMra1501993

Article  CAS  PubMed  PubMed Central  Google Scholar 

Prades J-M, Dumollard J-M, Timoshenko A, Chelikh L, Michel F, Estour B, Martin C (2002) Multinodular goiter: surgical management and histopathological findings. Eur Arch Otorhinolaryngol 259:217–221. https://doi.org/10.1007/s00405-002-0455-0

Article  PubMed  Google Scholar 

Pelizzo MR, Bernante P, Toniato A, Fassina A (1997) Frequency of thyroid carcinoma in a recent series of 539 consecutive thyroidectomies for multinodular goiter. Tumori 83:653–655. https://doi.org/10.1177/030089169708300305

Article  CAS  PubMed  Google Scholar 

Kim WG, Gong G, Kim EY, Kim TY, Hong SJ, Kim WB, Shong YK (2010) Concurrent occurrence of medullary thyroid carcinoma and papillary thyroid carcinoma in the same thyroid should be considered as coincidental. Clin Endocrinol (Oxf) 72(2):256–263. https://doi.org/10.1111/j.1365-2265.2009.03622.x

Article  PubMed  Google Scholar 

Machens A, Dralle H (2012) Simultaneous medullary and papillary thyroid cancer: a novel entity? Ann Surg Oncol 19:37–44. https://doi.org/10.1245/s10434-011-1795-z

Article  PubMed  Google Scholar 

Wong RL, Kazaure HS, Roman SA, Sosa JA (2012) Simultaneous medullary and differentiated thyroid cancer: a population-level analysis of an increasingly common entity. Ann Surg Oncol 19:2635–2642. https://doi.org/10.1245/s10434-012-2357-8

Article  PubMed  Google Scholar 

Appetecchia M, Lauretta R, Barnabei A, Pieruzzi L, Terrenato I, Cavedon E, Mian C, Castagna MG, Elisei R, SIE (Italian Society of Endocrinology) Working Group (2019) Epidemiology of simultaneous medullary and papillary thyroid carcinomas (MTC/PTC): an Italian multicenter study. Cancers (Basel) 11:1516. https://doi.org/10.3390/cancers11101516

Article  CAS  PubMed  Google Scholar 

Fallahi P, Patrizio A, Stoppini G, Elia G, Ragusa F, Paparo SR, Balestri E, Mazzi V, Botrini C, Varricchi G, Ulisse S, Ghionzoli M, Antonelli A, Ferrari SM (2023) Simultaneous occurrence of medullary thyroid carcinoma and papillary thyroid carcinoma: a case series with literature review. Curr Oncol 30:10237–10248. https://doi.org/10.3390/curroncol30120745

Article  PubMed  PubMed Central  Google Scholar 

Akgun E, Sager S, Beytur F, Nazari A, Ozturk T, Teksoz S, Sonmezoglu K (2023) Synchronous occurrence of medullary and papillary thyroid cancer and survival rates. Indian J Cancer 60:556–561. https://doi.org/10.4103/ijc.IJC_9_21

Article  PubMed  Google Scholar 

Wells SA, Asa SL, Dralle H, Elisei R, Evans DB, Gagel RF, Lee N, Machens A, Moley JF, Pacini F, Raue F, Frank-Raue K, Robinson B, Rosenthal MS, Santoro M, Schlumberger M, Shah M, Waguespack SG, American Thyroid Association Guidelines Task Force on Medullary Thyroid Carcinoma (2015) Revised American Thyroid Association guidelines for the management of medullary thyroid carcinoma. Thyroid 25(6):567–610. https://doi.org/10.1089/thy.2014.0335

Article  PubMed  PubMed Central  Google Scholar 

Papotti M, Volante M, Komminoth P, Sobrinho-Simões M, Bussolati G (2000) Thyroid carcinomas with mixed follicular and C-cell differentiation patterns. Semin Diagn Pathol 17:109–119

CAS  PubMed  Google Scholar