Abeshouse A, Adebamowo C, Adebamowo SN, Akbani R, Akeredolu T, Ally A, Anderson ML, Anur P, Appelbaum EL, Armenia J et al (2017) Comprehensive and integrated genomic characterization of adult soft tissue sarcomas. Cell 171:950–965e28. https://doi.org/10.1016/j.cell.2017.10.014
Article PubMed Central CAS Google Scholar
Ahlin C, Lundgren C, Embretsén-Varro E, Jirström K, Blomqvist C, Fjällskog M-L (2017) High expression of cyclin D1 is associated to high proliferation rate and increased risk of mortality in women with ER-positive but not in ER-negative breast cancers. Breast Cancer Res Treat 164:667–678. https://doi.org/10.1007/s10549-017-4294-5
Article PubMed PubMed Central CAS Google Scholar
Barrios C, Castresana JS, Kreicbergs A (1994) Clinicopathologic correlations and short-term prognosis in musculoskeletal sarcoma with c-Myc oncogene amplification. Am J Clin Oncol 17:273. https://doi.org/10.1097/00000421-199406000-00019
Article PubMed CAS Google Scholar
Binder M, Carr RM, Lasho TL, Finke CM, Mangaonkar AA, Pin CL, Berger KR, Mazzone A, Potluri S, Ordog T et al (2022) Oncogenic gene expression and epigenetic remodeling of cis-regulatory elements in ASXL1-mutant chronic myelomonocytic leukemia. Nat Commun 13:1434. https://doi.org/10.1038/s41467-022-29142-6
Article PubMed PubMed Central CAS Google Scholar
Brenca M, Maestro R (2015) Massive parallel sequencing in sarcoma pathobiology: state of the art and perspectives. Expert Rev Anticancer Ther 15:1473–1488. https://doi.org/10.1586/14737140.2015.1108192
Article PubMed CAS Google Scholar
Bui NQ, Przybyl J, Trabucco SE, Frampton G, Hastie T, van de Rijn M, Ganjoo KN (2019) A clinico-genomic analysis of soft tissue sarcoma patients reveals CDKN2A deletion as a biomarker for poor prognosis. Clin Sarcoma Res 9:12. https://doi.org/10.1186/s13569-019-0122-5
Article PubMed PubMed Central CAS Google Scholar
Chen S, Huang W, Luo P, Cai W, Yang L, Sun Z, Zheng B, Yan W, Wang C (2019) Undifferentiated pleomorphic sarcoma: long-term follow-up from a large institution. Cancer Manag Res 11:10001–10009. https://doi.org/10.2147/cmar.s226896
Article PubMed PubMed Central Google Scholar
Chudasama P, Renner M, Straub M, Mughal SS, Hutter B, Kosaloglu Z, Schweßinger R, Scheffler M, Alldinger I, Schimmack S et al (2017) Targeting fibroblast growth factor receptor 1 for treatment of soft-tissue sarcoma. Clin Cancer Res 23:962–973. https://doi.org/10.1158/1078-0432.ccr-16-0860
Article PubMed CAS Google Scholar
Doyle LA (2014) Sarcoma classification: an update based on the 2013 world health organization classification of tumors of soft tissue and bone. Cancer 120:1763–1774. https://doi.org/10.1002/cncr.28657
Fagundes R, Teixeira LK (2021) Cyclin E/CDK2: DNA replication, replication stress and genomic instability. Front Cell Dev Biol 9:774845. https://doi.org/10.3389/fcell.2021.774845
Article PubMed PubMed Central Google Scholar
Fiedorowicz M, Bartnik E, Sobczuk P, Teterycz P, Czarnecka AM (2019) Molecular biology of sarcoma. Oncol Clin Pract 14:307–330. https://doi.org/10.5603/ocp.2018.0045
Gaiser T, Hirsch D, Orouji A, Bach M, Kind P, Helbig D, Quaas A, Utikal J, Marx A, Gaiser MR (2018) MYC gene amplification is a rare event in atypical fibroxanthoma and pleomorphic dermal sarcoma. Oncotarget 9:21182–21189. https://doi.org/10.18632/oncotarget.24997
Article PubMed PubMed Central Google Scholar
Gounder MM, Agaram NP, Trabucco SE, Robinson V, Ferraro RA, Millis SZ, Krishnan A, Lee J, Attia S, Abida W et al (2022) Clinical genomic profiling in the management of patients with soft tissue and bone sarcoma. Nat Commun 13:3406. https://doi.org/10.1038/s41467-022-30496-0
Article PubMed PubMed Central CAS Google Scholar
Graaf WTA (2012) Pazopanib for metastatic Soft-Tissue sarcoma (PALETTE): A Randomised, Double-Blind, Placebo-Controlled phase 3 trial. Lancet 379:1879–1886. https://doi.org/10.1016/s0140-6736(12)60651-5. BlayJ.-Y.Chawla, S.P.; Kim, D.-W.; Bui-Nguyen, B.; Casali, P.G.; Schöffski, P.; Aglietta, M.; Staddon, A.P.; Beppu, Y.; et al
Gronchi A, Miah AB, Tos APD, Abecassis N, Bajpai J, Bauer S, Biagini R, Bielack S, Blay JY, Bolle S et al (2021) Soft tissue and visceral sarcomas: ESMO-EURACAN-GENTURIS clinical practice guidelines for diagnosis, treatment and follow-up☆. Ann Oncol 32:1348–1365. https://doi.org/10.1016/j.annonc.2021.07.006
Article PubMed CAS Google Scholar
Käcker C, Marx A, Mössinger K, Svehla F, Schneider U, Hogendoorn PCW, Nielsen OS, Küffer S, Sauer C, Fisher C et al (2013) High frequency of MYC gene amplification is a common feature of radiation-induced sarcomas. Further results from EORTC STBSG TL 01/01. Genes Chromosomes Cancer 52:93–98. https://doi.org/10.1002/gcc.22009
Article PubMed CAS Google Scholar
Kang E-Y, Weir A, Meagher NS, Farrington K, Nelson GS, Ghatage P, Lee C-H, Riggan MJ, Bolithon A, Popovic G et al (2023) CCNE1 and survival of patients with tubo-ovarian high-grade serous carcinoma: an ovarian tumor tissue analysis consortium study. Cancer 129:697–713. https://doi.org/10.1002/cncr.34582
Article PubMed CAS Google Scholar
Karst AM, Jones PM, Vena N, Ligon AH, Liu JF, Hirsch MS, Etemadmoghadam D, Bowtell DDL, Drapkin R (2014) Cyclin E1 deregulation occurs early in secretory cell transformation to promote formation of fallopian tube–derived high-grade serous ovarian cancers. Cancer Res 74:1141–1152. https://doi.org/10.1158/0008-5472.can-13-2247
Article PubMed CAS Google Scholar
Kresse SH, Ohnstad HO, Bjerkehagen B, Myklebost O, Meza-Zepeda LA (2010) DNA copy number changes in human malignant fibrous histiocytomas by array comparative genomic hybridisation. PLoS One 5:e15378. https://doi.org/10.1371/journal.pone.0015378
Article PubMed PubMed Central CAS Google Scholar
Lasota J, Miettinen M (2006) KIT and PDGFRA mutations in gastrointestinal stromal tumors (GISTs). Semin Diagn Pathol 23:91–102. https://doi.org/10.1053/j.semdp.2006.08.006
Li B, Li L, Li X, Wang Y, Xie Y, Liu C, Li F (2015) Undifferentiated pleomorphic sarcoma with Co-Existence of KRAS/PIK3CA mutations. Int J Clin Exp Pathol 8:8563–8567
PubMed PubMed Central Google Scholar
Ma J, Groisberg R, Shao C, Zhong W (2024) Incidence of undifferentiated pleomorphic sarcoma (UPS) in the United States. Sarcoma 2024:6735002. https://doi.org/10.1155/2024/6735002
Article PubMed PubMed Central Google Scholar
Mastrangelo G, Coindre J, Ducimetière F, Tos APD, Fadda E, Blay J, Buja A, Fedeli U, Cegolon L, Frasson A et al (2012) Incidence of soft tissue sarcoma and beyond. Cancer 118:5339–5348. https://doi.org/10.1002/cncr.27555
Mehren Mvon, Kane JM, Agulnik M, Bui MM, Carr-Ascher J, Choy E, Connelly M, Dry S, Ganjoo KN, Gonzalez RJ et al (2022) Soft tissue sarcoma, version 2.2022, NCCN clinical practice guidelines in oncology. J Natl Compr Canc Netw 20:815–833. https://doi.org/10.6004/jnccn.2022.0035
Mertens F, Fletcher CDM, Cin PD, Wever ID, Mandahl N, Mitelman F, Rosai J, Rydholm A, Sciot R, Tallini G et al (1998) Cytogenetic analysis of 46 pleomorphic soft tissue sarcomas and correlation with morphologic and clinical features: A report of the CHAMP study group. Genes Chromosom Cancer 22:16–25. https://doi.org/10.1002/(sici)1098-2264(199805)22:1%3C16::aid-gcc3%3E3.0.co;2-a
Article PubMed CAS Google Scholar
Mertens F, Antonescu CR, Mitelman F (2016) Gene fusions in soft tissue tumors: recurrent and overlapping pathogenetic themes. Genes Chromosom Cancer 55:291–310. https://doi.org/10.1002/gcc.22335
Article PubMed CAS Google Scholar
Mitra S, Farswan A, Piccinelli P, Sydow S, Hesla A, Tsagkozis P, Steyern FVvon, Almqvist M, Eriksson M, Magnusson L et al (2024) Transcriptomic profiles of myxofibrosarcoma and undifferentiated pleomorphic sarcoma correlate with clinical and genomic features. J Pathol 264:293–304. https://doi.org/10.1002/path.6347
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