Exploring the pathogenic mechanism of RNH1 in colorectal cancer based on eQTL, Multi-omics and deep learning

Anderson AC, Joller N, Kuchroo VK (2016) Lag-3, Tim-3, and TIGIT: co-inhibitory receptors with specialized functions in immune regulation. Immunity 44(5):989–1004

Article  CAS  PubMed  PubMed Central  Google Scholar 

Antona A, Leo G, Favero F et al (2023) Targeting lysine-specific demethylase 1 (KDM1A/LSD1) impairs colorectal cancer tumorigenesis by affecting cancer cells stemness, motility, and differentiation. Cell Death Discov 9(1):201

Article  CAS  PubMed  PubMed Central  Google Scholar 

Arnold M, Sierra MS, Laversanne M et al (2017) Global patterns and trends in colorectal cancer incidence and mortality. Gut 66(4):683–691

Article  PubMed  Google Scholar 

Balder HF, Vogel J, Jansen MCJF et al (2006) Heme and chlorophyll intake and risk of colorectal cancer in the Netherlands cohort study. Cancer Epidemiol Biomarkers Prev 15(4):717–725

Article  CAS  PubMed  Google Scholar 

Biller LH, Schrag D (2021) Diagnosis and treatment of metastatic colorectal cancer: a review. JAMA 325(7):669–685

Article  CAS  PubMed  Google Scholar 

Chu YM, Xu Y, Zou XQ et al (2022) DLC1 inhibits colon adenocarcinoma cell migration by promoting secretion of the neurotrophic factor MANF. Front Oncol 12:900166

Article  CAS  PubMed  PubMed Central  Google Scholar 

Dekker E, Tanis PJ, Vleugels JLA et al (2019) Colorectal cancer. Lancet 394(10207):1467–1480

Article  PubMed  Google Scholar 

Goldman MJ, Craft B, Hastie M et al (2020) Visualizing and interpreting cancer genomics data via the Xena platform. Nat Biotechnol 38(6):675–678

Article  CAS  PubMed  PubMed Central  Google Scholar 

Han B, He J, Chen Q et al (2023) ELFN1-AS1 promotes GDF15-mediated immune escape of colorectal cancer from NK cells by facilitating GCN5 and SND1 association. Discov Oncol 14(1):56

Article  PubMed  PubMed Central  Google Scholar 

Holowatyj AN, Ose J, Gigic B et al (2022) Higher vitamin B6 status is associated with improved survival among patients with stage I–III colorectal cancer. Am J Clin Nutr 116(2):303–313

Article  CAS  PubMed  PubMed Central  Google Scholar 

Hsu WH, LaBella KA, Lin Y et al (2023) Oncogenic KRAS drives lipofibrogenesis to promote angiogenesis and colon cancer progression. Cancer Discov 13(12):2652–2673

Article  CAS  PubMed  PubMed Central  Google Scholar 

Islam F, Chaousis S, Wahab R et al (2018) Protein interactions of FAM134B with EB1 and APC/beta-catenin in vitro in colon carcinoma. Mol Carcinog 57(11):1480–1491

Article  CAS  PubMed  Google Scholar 

Janesick A, Shelansky R, Gottscho AD et al (2023) High resolution mapping of the tumor microenvironment using integrated single-cell, spatial and in situ analysis. Nat Commun 14(1):8353

Article  CAS  PubMed  PubMed Central  Google Scholar 

Jiao S, Li C, Hao Q et al (2017) VGLL4 targets a TCF4–TEAD4 complex to coregulate Wnt and Hippo signalling in colorectal cancer. Nat Commun 8(1):14058

Article  CAS  PubMed  PubMed Central  Google Scholar 

Kang C, Zhang J, Xue M et al (2023) Metabolomics analyses of cancer tissue from patients with colorectal cancer[J]. Mol Med Rep 28(5):1–12

Article  Google Scholar 

Katzman JL, Shaham U, Cloninger A et al (2018) DeepSurv: personalized treatment recommender system using a Cox proportional hazards deep neural network[J]. BMC Med Res Methodol 18:1–12

Article  Google Scholar 

Kurki MI, Karjalainen J, Palta P et al (2023) Finngen provides genetic insights from a well-phenotyped isolated population. Nature 613(7944):508–518

Article  CAS  PubMed  PubMed Central  Google Scholar 

Laplante M, Sabatini DM (2012) mTOR signaling in growth control and disease. Cell 149(2):274–293

Article  CAS  PubMed  PubMed Central  Google Scholar 

Li T, Fu J, Zeng Z et al (2020) TIMER2. 0 for analysis of tumor-infiltrating immune cells. Nucleic Acids Res 48(W1):W509–W514

Article  CAS  PubMed  PubMed Central  Google Scholar 

Li J, Wu C, Hu H et al (2023) Remodeling of the immune and stromal cell compartment by PD-1 blockade in mismatch repair-deficient colorectal cancer. Cancer Cell 41(6):1152-1169. e7

Article  PubMed  Google Scholar 

Liu X, Zhuang L, Gan B (2024) Disulfidptosis: disulfide stress–induced cell death. Trends Cell Biol 34(4):327–337

Article  CAS  PubMed  Google Scholar 

Maalmi H, Walter V, Jansen L et al (2018) Dose-response relationship between serum retinol levels and survival in patients with colorectal cancer: results from the dachs study. Nutrients 10(4):510

Article  PubMed  PubMed Central  Google Scholar 

Machesky LM (2023) Deadly actin collapse by disulfidptosis. Nat Cell Biol 25(3):375–376

Article  CAS  PubMed  Google Scholar 

Maeser D, Gruener RF, Huang RS (2021) Oncopredict: an R package for predicting in vivo or cancer patient drug response and biomarkers from cell line screening data. Brief Bioinform 22(6):bbab260

Article  PubMed  PubMed Central  Google Scholar 

Marisa L, de Reyniès A, Duval A et al (2013) Gene expression classification of colon cancer into molecular subtypes: characterization, validation, and prognostic value. PLoS Med 10(5):e1001453

Article  CAS  PubMed  PubMed Central  Google Scholar 

Marks P, Garcia S, Barrio AM et al (2019) Resolving the full spectrum of human genome variation using linked-reads. Genome Res 29(4):635–645

Article  CAS  PubMed  PubMed Central  Google Scholar 

Mastropasqua F, Marzano F, Valletti A et al (2017) TRIM8 restores p53 tumour suppressor function by blunting N-MYC activity in chemo-resistant tumours[J]. Mol Cancer 16:1–16

Article  Google Scholar 

Powers HJ (2005) Interaction among folate, riboflavin, genotype, and cancer, with reference to colorectal and cervical cancer. J Nutr 135(12):2960S-2966S

Article  CAS  PubMed  Google Scholar 

Sarangdhar MA, Allam R (2021) Angiogenin (ANG)—ribonuclease inhibitor (RNH1) system in protein synthesis and disease. Int J Mol Sci 22(3):1287

Article  CAS  PubMed  PubMed Central  Google Scholar 

Satpathy AT, Granja JM, Yost KE et al (2019) Massively parallel single-cell chromatin landscapes of human immune cell development and intratumoral T cell exhaustion. Nat Biotechnol 37(8):925–936

Article  CAS  PubMed  PubMed Central  Google Scholar 

Shi J, Zhou L, Huang HS et al (2022) Repurposing oxiconazole against colorectal cancer via PRDX2-mediated autophagy arrest. Int J Biol Sci 18(9):3747

Article  CAS  PubMed  PubMed Central 

Comments (0)

No login
gif