Is age in children with Wilms tumour an important prognostic factor?

Results

Patients were divided by age into two groups: group 1 (888 (94,27%) patients age 0–9 years old) and group 2 (54 (5,73%) patients age 10–18 years old). In group 1, there were more patients at higher stage than in group 2 (p<0,05). The histology of low risk in group 1 versus group 2 occurred in 13,4% vs 3,7% patients, of intermediate risk in 66,2% vs 66,7% patients and high risk in 19,9% vs 29,6% patients. Results of treatment were assessed only in group 2 which is a limitation of this study. Overall 62,96% patients survived in this group.

Conclusion

Wilms tumour in children 10–18 years old is diagnosed at a higher stage and with worse histology. Overall survival in this age group is lower than in younger children, which is in line with the current literature.

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