Fan XX, Wu Q (2022) Decoding lung cancer at single-cell level. Front Immunol 13:883758
Article CAS PubMed PubMed Central Google Scholar
Hutchinson BD, Shroff GS, Truong MT, Ko JP (2019) Spectrum of lung adenocarcinoma. Semin Ultrasound CT MR 40:255–264
Thai AA, Solomon BJ, Sequist LV, Gainor JF, Heist RS (2021) Lung cancer. Lancet 398:535–554
Zhang Q, Xia T, Qi C, Du J, Ye C (2022) High expression of S100A2 predicts poor prognosis in patients with endometrial carcinoma. BMC Cancer 22:77
Article PubMed PubMed Central Google Scholar
Wang H, Hu X, Yang F, Xiao H (2021) Mir-325-3p promotes the proliferation, invasion, and EMT of breast cancer cells by directly targeting S100A2. Oncol Res 28:731–744
Article PubMed PubMed Central Google Scholar
Li C, Chen Q, Zhou Y, Niu Y, Wang X, Li X et al (2020) S100A2 promotes glycolysis and proliferation via GLUT1 regulation in colorectal cancer. Faseb j 34:13333–13344
Article CAS PubMed Google Scholar
Hountis P, Matthaios D, Froudarakis M, Bouros D, Kakolyris S (2014) S100A2 protein and non-small cell lung cancer. The dual role concept. Tumour Biol 35:7327–7333
Article CAS PubMed Google Scholar
Sugino H, Sawada Y (2022) Influence of S100A2 in human diseases. Diagnostics. https://doi.org/10.3390/diagnostics12071756
Article PubMed PubMed Central Google Scholar
Zeng T, Ren W, Zeng H, Wang D, Wu X, Xu G (2024) Tfap2a activates S100A2 to mediate glutamine metabolism and promote lung adenocarcinoma metastasis. Clin Respir J 18:e13825
Article CAS PubMed PubMed Central Google Scholar
Yuan R, Liu Q, Segeren HA, Yuniati L, Guardavaccaro D, Lebbink RJ et al (2019) Cyclin F-dependent degradation of E2F7 is critical for DNA repair and G2-phase progression. EMBO J 38:e101430
Article CAS PubMed PubMed Central Google Scholar
Guo X, Liu L, Zhang Q, Yang W, Zhang Y (2020) E2F7 transcriptionally inhibits MicroRNA-199b expression to promote USP47, thereby enhancing colon cancer tumor stem cell activity and promoting the occurrence of colon cancer. Front Oncol 10:565449
Yang R, Wang M, Zhang G, Bao Y, Wu Y, Li X et al (2020) E2F7-EZH2 axis regulates PTEN/AKT/mTOR signalling and glioblastoma progression. Br J Cancer 123:1445–1455
Article CAS PubMed PubMed Central Google Scholar
Fu L, Li Z, Wu Y, Zhu T, Ma Z, Dong L et al (2023) Hsa-miR-195-5p inhibits autophagy and gemcitabine resistance of lung adenocarcinoma cells via E2F7/CEP55. Biochem Genet 61:1528–1547
Article CAS PubMed Google Scholar
Chen Y, Wang C, Song J, Xu R, Ruze R, Zhao Y (2021) S100A2 is a prognostic biomarker involved in immune infiltration and predict immunotherapy response in pancreatic cancer. Front Immunol 12:758004
Article CAS PubMed PubMed Central Google Scholar
Li W, Wang Z, Lin R, Huang S, Miao H, Zou L et al (2022) Lithocholic acid inhibits gallbladder cancer proliferation through interfering glutaminase-mediated glutamine metabolism. Biochem Pharmacol 205:115253
Article CAS PubMed Google Scholar
Hanahan D, Weinberg RA (2011) Hallmarks of cancer: the next generation. Cell 144:646–674
Article CAS PubMed Google Scholar
Cerezo M, Rocchi S (2020) Cancer cell metabolic reprogramming: a keystone for the response to immunotherapy. Cell Death Dis 11:964
Article PubMed PubMed Central Google Scholar
Yu Q, Tu H, Yin X, Peng C, Dou C, Yang W et al (2022) Targeting glutamine metabolism ameliorates autoimmune hepatitis via inhibiting T cell activation and differentiation. Front Immunol 13:880262
Article CAS PubMed PubMed Central Google Scholar
Yang R, Li X, Wu Y, Zhang G, Liu X, Li Y et al (2020) EGFR activates GDH1 transcription to promote glutamine metabolism through MEK/ERK/ELK1 pathway in glioblastoma. Oncogene 39:2975–2986
Article CAS PubMed Google Scholar
Akar S, Donmez-Altuntas H, Hamurcu Z (2022) β-escin reduces cancer progression in aggressive MDA-MB-231 cells by inhibiting glutamine metabolism through downregulation of c-myc oncogene. Mol Biol Rep 49:7409–7415
Article CAS PubMed Google Scholar
Edwards DN, Ngwa VM, Raybuck AL, Wang S, Hwang Y, Kim LC et al (2021) Selective glutamine metabolism inhibition in tumor cells improves antitumor T lymphocyte activity in triple-negative breast cancer. J Clin Invest. https://doi.org/10.1172/JCI140100
Article PubMed PubMed Central Google Scholar
Byun JK, Park M, Lee S, Yun JW, Lee J, Kim JS et al (2020) Inhibition of glutamine utilization synergizes with immune checkpoint inhibitor to promote antitumor immunity. Mol Cell 80:592-606.e8
Article CAS PubMed Google Scholar
Lemberg KM, Vornov JJ, Rais R, Slusher BS (2018) We’re Not “DON” Yet: Optimal Dosing and Prodrug Delivery of 6-Diazo-5-oxo-L-norleucine. Mol Cancer Ther 17:1824–1832
Article CAS PubMed PubMed Central Google Scholar
Zhang J, Wang Z, Liang Z, Jin C, Shi Y, Fan M et al (2023) Nfic1 inhibits the migration and invasion of MDA-MB-231 cells through S100A2-mediated inactivation of MEK/ERK pathway. Arch Biochem Biophys 734:109497
Article CAS PubMed Google Scholar
Liu YF, Liu QQ, Wang X, Luo CH (2014) Clinical significance of S100A2 expression in gastric cancer. Tumour Biol 35:3731–3741
Article CAS PubMed Google Scholar
Han F, Zhang L, Liao S, Zhang Y, Qian L, Hou F et al (2022) The interaction between S100A2 and KPNA2 mediates NFYA nuclear import and is a novel therapeutic target for colorectal cancer metastasis. Oncogene 41:657–670
Article CAS PubMed Google Scholar
Feng G, Xu X, Youssef EM, Lotan R (2001) Diminished expression of S100A2, a putative tumor suppressor, at early stage of human lung carcinogenesis. Cancer Res 61:7999–8004
Wang T, Liang Y, Thakur A, Zhang S, Liu F, Khan H et al (2017) Expression and clinicopathological significance of S100 calcium binding protein A2 in lung cancer patients of Chinese Han ethnicity. Clin Chim Acta 464:118–122
Article CAS PubMed Google Scholar
Lin D, Zhao W, Yang J, Wang H, Zhang H (2022) Integrative analysis of biomarkers and mechanisms in adamantinomatous craniopharyngioma. Front Genet 13:830793
Article CAS PubMed PubMed Central Google Scholar
Xiang S, Wang Z, Ye Y, Zhang F, Li H, Yang Y et al (2019) E2F1 and E2F7 differentially regulate KPNA2 to promote the development of gallbladder cancer. Oncogene 38:1269–1281
Article CAS PubMed Google Scholar
Ling S, Zhan Q, Jiang G, Shan Q, Yin L, Wang R et al (2022) E2F7 promotes mammalian target of ra
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