Segmentectomy or Lobectomy in T1N0M0 Non-Small Cell Lung Carcinomas: The Prognostic Role of Histology and Vascular Invasion

Yu KR, Julliard WA (2024) Sublobar resection of non-small-cell lung cancer: wedge resection vs. segmentectomy. Curr Oncol 29(5):2497–2507

Article  Google Scholar 

Bade BC, Dela Cruz CS (2020) Lung cancer: epidemiology, etiology, and prevention. Clin Chest Med. 2020;41(1):1–24

Alexander M, Kim SY, Cheng H (2020) Management of non-small cell lung cancer. Lung 2020;198(6):897–907

Wang Y, Zou S, Zhao Z, Liu P, Ke C, Xu S (2020) New insights into small-cell lung cancer development and therapy. Cell Biol Int 44(8):1564–1576

Article  PubMed  PubMed Central  Google Scholar 

Wang RR, Li MJ, Peng Q, Huang ZY, Wu LL, Xie D (2024) Validation of the 9th edition of the TNM staging system for non-small cell lung cancer with lobectomy in stage IA-IIIA. Eur J Cardiothorac Surg 65(3):ezae071

Article  PubMed  Google Scholar 

Alduais Y, Zhang H, Fan F, Chen J, Chen B (2023) Non-small cell lung cancer (NSCLC): A review of risk factors, diagnosis, and treatment. Medicine (Baltimore) 102(8):e32899

Article  CAS  PubMed  PubMed Central  Google Scholar 

Ginsberg RJ, Rubinstein LV (1995) Randomized trial of lobectomy versus limited resection for T1 N0 non-small cell lung cancer. Lung Cancer Study Group. Ann Thorac Surg 60(3):615–622 discussion 622-3

Article  CAS  PubMed  Google Scholar 

Ginsberg RJ (1997) Resection of non-small cell lung cancer: how much and by what route. Chest 112(4 Suppl):203S–205S

Article  CAS  PubMed  Google Scholar 

Saji H, Okada M, Tsuboi M, Nakajima R, Suzuki K, Aokage K, Aoki T, Okami J, Yoshino I, Ito H, Okumura N, Yamaguchi M, Ikeda N, Wakabayashi M, Nakamura K, Fukuda H, Nakamura S, Mitsudomi T, Watanabe SI, Asamura H, West Japan Oncology Group and Japan Clinical Oncology Group (2022) Segmentectomy versus lobectomy in small-sized peripheral non-small-cell lung cancer (JCOG0802/WJOG4607L): a multicentre, open-label, phase 3, randomised, controlled, non-inferiority trial. Lancet 23(10335):1607–1617

Article  Google Scholar 

Altorki N, Wang X, Damman B, Mentlick J, Landreneau R, Wigle D, Jones DR, Conti M, Ashrafi AS, Liberman M, de Perrot M, Mitchell JD, Keenan R, Bauer T, Miller D, Stinchcombe TE (2024) Lobectomy, segmentectomy, or wedge resection for peripheral clinical T1aN0 non-small cell lung cancer: A post hoc analysis of CALGB 140503 (Alliance). J Thorac Cardiovasc Surg 167(1):338–347e1

Article  PubMed  Google Scholar 

Aokage K, Suzuki K, Saji H, Wakabayashi M, Kataoka T, Sekino Y, Fukuda H, Endo M, Hattori A, Mimae T, Miyoshi T, Isaka M, Yoshioka H, Nakajima R, Nakagawa K, Okami J, Ito H, Kuroda H, Tsuboi M, Okumura N, Takahama M, Ohde Y, Aoki T, Tsutani Y, Okada M, Watanabe SI (2023) Japan Clinical Oncology Group. Segmentectomy for ground-glass-dominant lung cancer with a tumour diameter of 3 cm or less including ground-glass opacity (JCOG1211): a multicentre, single-arm, confirmatory, phase 3 trial. Lancet Respir Med 11(6):540–549

Article  CAS  PubMed  Google Scholar 

Nomori H (2014) Segmentectomy for c-T1N0M0 non-small cell lung cancer. Surg Today 44(5):812–819

Article  PubMed  Google Scholar 

Hennon M, Landreneau RJ (2018) Role of segmentectomy in treatment of early-stage non-small cell lung cancer. Ann Surg Oncol 25(1):59–63

Article  PubMed  Google Scholar 

Maniwa T, Okami J, Miyoshi T, Wakabayashi M, Yoshioka H, Mimae T, Endo M, Hattori A, Nakagawa K, Isaka T, Isaka M, Kita R, Sekino Y, Mitome N, Aokage K, Saji H, Nakajima R, Okada M, Tsuboi M, Asamura H, Fukuda H, Watanabe SI (2024) West Japan Oncology Group and Japan Clinical Oncology Group. Lymph node dissection in small peripheral lung cancer: Supplemental analysis of JCOG0802/WJOG4607L. J Thorac Cardiovasc Surg 168(3):674–683e1

Article  PubMed  Google Scholar 

Lutfi W, Schuchert MJ, Dhupar R, Ekeke C, Sarkaria IS, Christie NA, Luketich JD, Okusanya OT (2019) Node-positive segmentectomy for non-small-cell lung cancer: risk factors and outcomes. Clin Lung Cancer 20(4):e463–e469

Article  PubMed  PubMed Central  Google Scholar 

Koike T, Yamato Y, Yoshiya K, Toyabe S (2012) Prognostic predictors in non-small cell lung cancer patients undergoing intentional segmentectomy. Ann Thorac Surg 93(6):1788–1794

Article  PubMed  Google Scholar 

Ikeda T, Kadota K, Go T, Misaki N, Haba R, Yokomise H (2023) Segmentectomy provides comparable outcomes to lobectomy for stage ia non-small cell lung cancer with spread through air spaces. Semin Thorac Cardiovasc Surg 35(1):156–163

Article  PubMed  Google Scholar 

Mathey-Andrews C, Abruzzo AR, Venkateswaran S, Potter AL, Senthil P, Beqari J, Yang CJ, Lanuti M (2024) Segmentectomy vs lobectomy for early non-small cell lung cancer with visceral pleural invasion. Ann Thorac Surg 117(5):1007–1014

Article  PubMed  Google Scholar 

Stanley S, Braaten M, Mishra A, Abdul Jabbar AB, Asghar MS, Tauseef A, Silberstein P, Balters M, Gillaspie E, DeVrieze B (2025) Lobectomy vs segmentectomy in stage I non-small cell lung cancer with lymphatic vascular invasion. Ann Thorac Surg Short Rep 7(2):304–307

Article  Google Scholar 

Chan EG, Chan PG, Mazur SN, Normolle DP, Luketich JD, Landreneau RJ, Schuchert MJ (2021) Outcomes with segmentectomy versus lobectomy in patients with clinical T1cN0M0 non-small cell lung cancer. J Thorac Cardiovasc Surg 161:1639–1648

Article  PubMed  Google Scholar 

Comments (0)

No login
gif