Loh, J. J. & Ma, S. Hallmarks of cancer stemness. Cell Stem Cell 31, 617–639 (2024).
Article CAS PubMed Google Scholar
Batlle, E. & Clevers, H. Cancer stem cells revisited. Nat. Med. 23, 1124–1134 (2017).
Article CAS PubMed Google Scholar
Chu, X. et al. Cancer stem cells: advances in knowledge and implications for cancer therapy. Signal Transduct. Target. Ther. 9, 170 (2024).
Article CAS PubMed PubMed Central Google Scholar
Tiriac, H. et al. Organoid profiling identifies common responders to chemotherapy in pancreatic cancer. Cancer Discov. 8, 1112–1129 (2018).
Article CAS PubMed PubMed Central Google Scholar
Vojnits, K. et al. Targeting of human cancer stem cells predicts efficacy and toxicity of FDA-approved oncology drugs. Cancer Lett. 599, 217108 (2024).
Article CAS PubMed Google Scholar
Yang, L. et al. Targeting cancer stem cell pathways for cancer therapy. Signal Transduct. Target. Ther. 5, 8 (2020).
Article PubMed PubMed Central Google Scholar
Tarnok, A. Cancer and cytometry. Cytometry A 95, 257–258 (2019).
Lan, L. & Behrens, A. Are there specific cancer stem cell markers?. Cancer Res. 83, 170–172 (2023).
Article CAS PubMed PubMed Central Google Scholar
Reynolds, B. A. & Weiss, S. Generation of neurons and astrocytes from isolated cells of the adult mammalian central nervous system. Science 255, 1707–1710 (1992).
Article CAS PubMed Google Scholar
Johnson, S., Chen, H. & Lo, P. K. In vitro tumorsphere formation assays. Bio Protoc. 3, e325 (2013).
Article PubMed PubMed Central Google Scholar
Loeb, L. A. & Harris, C. C. Advances in chemical carcinogenesis: a historical review and prospective. Cancer Res. 68, 6863–6872 (2008).
Article CAS PubMed PubMed Central Google Scholar
Grivennikov, S. I., Greten, F. R. & Karin, M. Immunity, inflammation, and cancer. Cell 140, 883–899 (2010).
Article CAS PubMed PubMed Central Google Scholar
Siddiqui, I. A., Sanna, V., Ahmad, N., Sechi, M. & Mukhtar, H. Resveratrol nanoformulation for cancer prevention and therapy. Ann. N. Y. Acad. Sci. 1348, 20–31 (2015).
Article CAS PubMed Google Scholar
Qureshi-Baig, K., Ullmann, P., Haan, S. & Letellier, E. Tumor-initiating cells: a criTICal review of isolation approaches and new challenges in targeting strategies. Mol. Cancer 16, 40 (2017).
Article PubMed PubMed Central Google Scholar
Weiswald, L. B., Bellet, D. & Dangles-Marie, V. Spherical cancer models in tumor biology. Neoplasia 17, 1–15 (2015).
Article PubMed PubMed Central Google Scholar
Li, Y. & Zhang, T. Targeting cancer stem cells by curcumin and clinical applications. Cancer Lett. 346, 197–205 (2014).
Article CAS PubMed Google Scholar
Manuel Iglesias, J. et al. Mammosphere formation in breast carcinoma cell lines depends upon expression of E-cadherin. PLoS ONE 8, e77281 (2013).
Article PubMed PubMed Central Google Scholar
Ginestier, C. et al. ALDH1 is a marker of normal and malignant human mammary stem cells and a predictor of poor clinical outcome. Cell Stem Cell 1, 555–567 (2007).
Article CAS PubMed PubMed Central Google Scholar
Tanei, T. et al. Association of breast cancer stem cells identified by aldehyde dehydrogenase 1 expression with resistance to sequential Paclitaxel and epirubicin-based chemotherapy for breast cancers. Clin. Cancer Res. 15, 4234–4241 (2009).
Article CAS PubMed Google Scholar
Lee, Y., Guan, G. & Bhagat, A. A. ClearCell(R) FX, a label-free microfluidics technology for enrichment of viable circulating tumor cells. Cytometry A 93, 1251–1254 (2018).
Shirai, K. et al. Hybrid double-spiral microfluidic chip for RBC-lysis-free enrichment of rare cells from whole blood. Lab Chip 22, 4418–4429 (2022).
Article CAS PubMed Google Scholar
den Hollander, P. et al. Limiting dilution tumor initiation assay: an in vivo approach for the study of cancer stem cells. Methods Mol. Biol. 2429, 547–554 (2022).
Bonnay, F. et al. Oxidative metabolism drives immortalization of neural stem cells during tumorigenesis. Cell 182, 1490–1507 (2020).
Article CAS PubMed Google Scholar
Vlachogiannis, G. et al. Patient-derived organoids model treatment response of metastatic gastrointestinal cancers. Science 359, 920–926 (2018).
Article CAS PubMed PubMed Central Google Scholar
Gao, D. et al. Organoid cultures derived from patients with advanced prostate cancer. Cell 159, 176–187 (2014).
Article CAS PubMed PubMed Central Google Scholar
Yao, Y. et al. Patient-derived organoids predict chemoradiation responses of locally advanced rectal cancer. Cell Stem Cell 26, 17–26 (2020).
Article CAS PubMed Google Scholar
Chen, P. et al. Patient-derived organoids can guide personalized-therapies for patients with advanced breast cancer. Adv. Sci. 8, e2101176 (2021).
Broutier, L. et al. Human primary liver cancer-derived organoid cultures for disease modeling and drug screening. Nat. Med. 23, 1424–1435 (2017).
Article CAS PubMed PubMed Central Google Scholar
Jacob, F. et al. A patient-derived glioblastoma organoid model and biobank recapitulates inter- and intra-tumoral heterogeneity. Cell 180, 188–204.e22 (2020).
Article CAS PubMed Google Scholar
Yin, S. et al. Patient-derived tumor-like cell clusters for drug testing in cancer therapy. Sci. Transl. Med. 12, (2020).
Joensuu, H. et al. Adjuvant capecitabine for early breast cancer: 15-year overall survival results from a randomized trial. J. Clin. Oncol. 40, 1051–1058 (2022).
Article CAS PubMed PubMed Central Google Scholar
Pece, S. et al. Biological and molecular heterogeneity of breast cancers correlates with their cancer stem cell content. Cell 140, 62–73 (2010).
Article CAS PubMed Google Scholar
Bushnell, G. G. et al. Natural killer cell regulation of breast cancer stem cells mediates metastatic dormancy. Cancer Res. 84, 3337–3353 (2024).
Comments (0)