Ashton NJ, Benedet AL, Molfetta GD, Pola I, Anastasi F, Fernández-Lebrero A et al (2025) Biomarker discovery in Alzheimer’s and neurodegenerative diseases using nucleic acid linked immuno-sandwich assay. Alzheimers Dement 21:e14621. https://doi.org/10.1002/alz.14621

Article  PubMed  PubMed Central  Google Scholar 

Ashton NJ, Brum WS, Di Molfetta G, Benedet AL, Arslan B, Jonaitis E et al (2024) Diagnostic accuracy of a plasma phosphorylated Tau 217 immunoassay for Alzheimer disease pathology. JAMA Neurol 81:255–263. https://doi.org/10.1001/jamaneurol.2023.5319

Article  PubMed  PubMed Central  Google Scholar 

Atri A, Locascio JJ, Lin JM, Yap L, Dickerson BC, Grodstein F et al (2005) Prevalence and effects of lobar microhemorrhages in early-stage dementia. Neurodegener Dis 2:305–312. https://doi.org/10.1159/000092317

Article  PubMed  Google Scholar 

Banerjee G, Ambler G, Keshavan A, Paterson RW, Foiani MS, Toombs J et al (2020) Cerebrospinal fluid biomarkers in cerebral amyloid angiopathy. J Alzheimers Dis 74:1189–1201. https://doi.org/10.3233/JAD-191254

Article  CAS  PubMed  PubMed Central  Google Scholar 

Banerjee G, Carare R, Cordonnier C, Greenberg SM, Schneider JA, Smith EE et al (2017) The increasing impact of cerebral amyloid angiopathy: essential new insights for clinical practice. J Neurol Neurosurg Psychiatry 88:982–994. https://doi.org/10.1136/jnnp-2016-314697

Article  PubMed  PubMed Central  Google Scholar 

Beach TG, Adler CH, Sue LI, Serrano G, Shill HA, Walker DG et al (2015) Arizona study of aging and neurodegenerative disorders and brain and body donation program. Neuropathology 35:354–389. https://doi.org/10.1111/neup.12189

Article  PubMed  PubMed Central  Google Scholar 

Beach TG, Malek-Ahmadi M (2021) Alzheimer’s disease neuropathological comorbidities are common in the younger-old. J Alzheimers Dis 79:389–400. https://doi.org/10.3233/JAD-201213

Article  CAS  PubMed  PubMed Central  Google Scholar 

Beach TG, Serrano GE, Driver-Dunckley ED, Sue LI, Shill HA, Mehta SH et al (2025) Parkinson disease neuropathological comorbidities: prevalences from younger-old to older-old, with comparison to non-demented, non-parkinsonian subjects. medRxiv. https://doi.org/10.1101/2025.01.13.25319971

Article  PubMed  PubMed Central  Google Scholar 

Benedet AL, Brum WS, Hansson O, Alzheimer’s Disease Neuroimaging Initiative, Karikari TK, Zimmer ER et al (2022) The accuracy and robustness of plasma biomarker models for amyloid PET positivity. Alzheimers Res Ther 14:26. https://doi.org/10.1186/s13195-021-00942-0

Article  CAS  PubMed  PubMed Central  Google Scholar 

Besser LM, Kukull WA, Teylan MA, Bigio EH, Cairns NJ, Kofler JK et al (2018) The Revised National Alzheimer’s Coordinating Center’s Neuropathology Form—available data and new analyses. J Neuropathol Exp Neurol 77:717–726. https://doi.org/10.1093/jnen/nly049

Article  CAS  PubMed  PubMed Central  Google Scholar 

Biffi A, Greenberg SM (2011) Cerebral amyloid angiopathy: a systematic review. J Clin Neurol Seoul 7:1–9. https://doi.org/10.3988/jcn.2011.7.1.1

Article  Google Scholar 

Bornebroek M, De Jonghe C, Haan J, Kumar-Singh S, Younkin S, Roos R et al (2003) Hereditary cerebral hemorrhage with amyloidosis Dutch type (AbetaPP 693): decreased plasma amyloid-beta 42 concentration. Neurobiol Dis 14:619–623. https://doi.org/10.1016/j.nbd.2003.08.019

Article  CAS  PubMed  Google Scholar 

Braak H, Alafuzoff I, Arzberger T, Kretzschmar H, Del Tredici K (2006) Staging of Alzheimer disease-associated neurofibrillary pathology using paraffin sections and immunocytochemistry. Acta Neuropathol (Berl) 112:389–404. https://doi.org/10.1007/s00401-006-0127-z

Article  PubMed  PubMed Central  Google Scholar 

Braak H, Braak E (1991) Demonstration of amyloid deposits and neurofibrillary changes in whole brain sections. Brain Pathol 1:213–216. https://doi.org/10.1111/j.1750-3639.1991.tb00661.x

Article  CAS  PubMed  Google Scholar 

Bregman N, Nathan T, Shir D, Omer N, Levy MH, David AB et al (2025) Lecanemab in clinical practice: real-world outcomes in early Alzheimer’s disease. Alzheimers Res Ther 17:119. https://doi.org/10.1186/s13195-025-01763-1

Article  CAS  PubMed  PubMed Central  Google Scholar 

van den Brink H, Voigt S, Kozberg M, van Etten ES (2024) The role of neuroinflammation in cerebral amyloid angiopathy. EBioMedicine 110:105466. https://doi.org/10.1016/j.ebiom.2024.105466

Article  CAS  PubMed  PubMed Central  Google Scholar 

Chantran Y, Capron J, Alamowitch S, Aucouturier P (2019) Anti-Aβ antibodies and cerebral amyloid angiopathy complications. Front Immunol 10:1534. https://doi.org/10.3389/fimmu.2019.01534

Article  CAS  PubMed  PubMed Central  Google Scholar 

Charidimou A, Boulouis G, Frosch MP, Baron J-C, Pasi M, Albucher JF et al (2022) The Boston criteria version 2.0 for cerebral amyloid angiopathy: a multicentre, retrospective, MRI-neuropathology diagnostic accuracy study. Lancet Neurol 21:714–725. https://doi.org/10.1016/S1474-4422(22)00208-3

Article  PubMed  Google Scholar 

Charidimou A, Farid K, Tsai H-H, Tsai L-K, Yen R-F, Baron J-C (2018) Amyloid-PET burden and regional distribution in cerebral amyloid angiopathy: a systematic review and meta-analysis of biomarker performance. J Neurol Neurosurg Psychiatry 89:410–417. https://doi.org/10.1136/jnnp-2017-316851

Article  PubMed  Google Scholar 

Charidimou A, Martinez-Ramirez S, Reijmer YD, Oliveira-Filho J, Lauer A, Roongpiboonsopit D et al (2016) Total magnetic resonance imaging burden of small vessel disease in cerebral amyloid angiopathy: an imaging-pathologic study of concept validation. JAMA Neurol 73:994–1001. https://doi.org/10.1001/jamaneurol.2016.0832

Article  PubMed  PubMed Central  Google Scholar 

Charidimou A, Zonneveld HI, Shams S, Kantarci K, Shoamanesh A, Hilal S et al (2019) APOE and cortical superficial siderosis in CAA: meta-analysis and potential mechanisms. Neurology 93:e358–e371. https://doi.org/10.1212/WNL.0000000000007818

Article  CAS  PubMed  PubMed Central  Google Scholar 

Chatterjee P, Tegg M, Pedrini S, Fagan AM, Xiong C, Singh AK et al (2021) Plasma Amyloid-Beta levels in a pre-symptomatic Dutch-type hereditary cerebral amyloid angiopathy pedigree: a cross-sectional and longitudinal investigation. Int J Mol Sci 22:2931. https://doi.org/10.3390/ijms22062931

Article  CAS  PubMed  PubMed Central  Google Scholar 

Cogswell PM, Barakos JA, Barkhof F, Benzinger TS, Jack CR, Poussaint TY et al (2022) Amyloid-related imaging abnormalities with emerging Alzheimer disease therapeutics: detection and reporting recommendations for clinical practice. AJNR Am J Neuroradiol 43:E19–E35. https://doi.org/10.3174/ajnr.A7586

Article  CAS  PubMed  PubMed Central  Google Scholar 

Crous-Bou M, Minguillón C, Gramunt N, Molinuevo JL (2017) Alzheimer’s disease prevention: from risk factors to early intervention. Alzheimers Res Ther 9:71. https://doi.org/10.1186/s13195-017-0297-z

Article  CAS  PubMed  PubMed Central  Google Scholar 

De Kort AM, Kuiperij HB, Jäkel L, Kersten I, Rasing I, Van Etten ES et al (2023) Plasma amyloid beta 42 is a biomarker for patients with hereditary, but not sporadic, cerebral amyloid angiopathy.