Alahari SK 2003 Nischarin inhibits Rac induced migration and invasion of epithelial cells by affecting signaling cascades involving PAK. Exp. Cell Res. 288 415–424

Article  CAS  PubMed  Google Scholar 

Alahari SK, Lee JW and Juliano RL 2000 Nischarin, a novel protein that interacts with the integrin alpha5 subunit and inhibits cell migration. J. Cell Biol. 151 1141–1154

Article  CAS  PubMed  PubMed Central  Google Scholar 

Bukhari AA, Zhang X, Li M, et al. 2020 Cofilin participates in regulating alpha-epithelial sodium channel by interaction with 14-3-3 isoforms. J. Biomed. Res. 34 351–360

Article  CAS  PubMed  PubMed Central  Google Scholar 

Casanova-Sepúlveda G and Boggon TJ 2025 Regulation and signaling of the LIM domain kinases. Bioessays 47 e2400184

Article  PubMed  Google Scholar 

Cross EM, Marin O, Ariawan D, et al. 2024 Structural determinants of phosphorylation-dependent nuclear transport of HCMV DNA polymerase processivity factor UL44. FEBS Lett. 598 199–209

Article  CAS  PubMed  Google Scholar 

Ding Y, Li Y, Lu L, et al. 2015 Inhibition of Nischarin expression promotes neurite outgrowth through regulation of PAK activity. PLoS One 10 e0144948

Article  PubMed  PubMed Central  Google Scholar 

Ding Y, Milosavljevic T and Alahari SK 2008 Nischarin inhibits LIM kinase to regulate cofilin phosphorylation and cell invasion. Mol. Cell Biol. 28 3742–3756

Article  CAS  PubMed  PubMed Central  Google Scholar 

Ding Y, Zhang R, Zhang K, et al. 2013 Nischarin is differentially expressed in rat brain and regulates neuronal migration. PLoS One 8 e54563

Article  CAS  PubMed  PubMed Central  Google Scholar 

Frotscher M, Studer D, Graber W, et al. 2014 Fine structure of synapses on dendritic spines. Front. Neuroanat. 8 94

Article  PubMed  PubMed Central  Google Scholar 

Goode BL, Eskin J and Shekhar S 2023 Mechanisms of actin disassembly and turnover. J. Cell Biol. 222 e202309021

Article  CAS  PubMed  PubMed Central  Google Scholar 

Ishii K, Kohno T, Sakai K, et al. 2023 Reelin regulates the migration of late-born hippocampal CA1 neurons via cofilin phosphorylation. Mol. Cell Neurosci. 124 103794

Article  CAS  PubMed  Google Scholar 

Lei W, Myers KR, Rui Y, et al. 2017 Phosphoinositide-dependent enrichment of actin monomers in dendritic spines regulates synapse development and plasticity. J. Cell Biol. 216 2551–2564

Article  CAS  PubMed  PubMed Central  Google Scholar 

Li L, Zhang W, Chai X, et al. 2014 Neuronal maturation and laminar formation in the chicken optic tectum are accompanied by the transition of phosphorylated cofilin from cytoplasm to nucleus. Gene Expr. Patterns 16 75–85

Article  CAS  PubMed  Google Scholar 

Liu Y, You H, Li H, et al. 2024 TaNAC1 boosts powdery mildew resistance by phosphorylation-dependent regulation of TaSec1a and TaCAMTA4 via PP2Ac/CDPK20. New Phytol. 244 635–653

Article  CAS  PubMed  Google Scholar 

Maziveyi M and Alahari SK 2015 Breast cancer tumor suppressors: A special emphasis on novel protein Nischarin. Cancer Res. 75 4252–4259

Article  CAS  PubMed  Google Scholar 

Namme JN, Bepari AK and Takebayashi H 2021 Cofilin signaling in the CNS physiology and neurodegeneration. Int. J. Mol. Sci. 22 10727

Article  CAS  PubMed  PubMed Central  Google Scholar 

Nishita M, Tomizawa C, Yamamoto M, et al. 2005 Spatial and temporal regulation of cofilin activity by LIM kinase and Slingshot is critical for directional cell migration. J. Cell Biol. 171 349–359

Article  CAS  PubMed  PubMed Central  Google Scholar 

Okpechi SC, Yousefi H, Nguyen K, et al. 2022 Role of Nischarin in the pathology of diseases: a special emphasis on breast cancer. Oncogene 41 1079–1086

Article  CAS  PubMed  Google Scholar 

Oosterheert W, Boiero Sanders M, Bieling P, et al. 2025 Structural insights into actin filament turnover. Trends Cell Biol. 35 893–906

Reddig PJ, Xu D and Juliano RL 2005 Regulation of p21-activated kinase-independent Rac1 signal transduction by nischarin. J. Biol. Chem. 280 30994–31002

Article  CAS  PubMed  Google Scholar 

Sousa-Squiavinato ACM, Rocha MR, Barcellos-de-Souza P, et al. 2019 Cofilin-1 signaling mediates epithelial-mesenchymal transition by promoting actin cytoskeleton reorganization and cell-cell adhesion regulation in colorectal cancer cells. Biochim. Biophys. Acta Mol. Cell Res. 1866 418–429

Article  CAS  PubMed  Google Scholar 

Stern S, Haverkamp S, Sinske D, et al. 2013 The transcription factor serum response factor stimulates axon regeneration through cytoplasmic localization and cofilin interaction. J. Neurosci. 33 18836–18848

Article  CAS  PubMed  PubMed Central  Google Scholar 

Tripathi K, Demiray YE, Kliche S, et al. 2021 Reducing glutamic acid decarboxylase in the dorsal dentate gyrus attenuates juvenile stress induced emotional and cognitive deficits. Neurobiol. Stress 15 100350

Wang W and Townes-Anderson E 2016 Lim kinase, a bi-functional effector in injury-induced structural plasticity of synapses. Neural Regen. Res. 11 1029–1032

Article  CAS  PubMed  PubMed Central  Google Scholar 

Wen Z, Han L, Bamburg JR, et al. 2007 BMP gradients steer nerve growth cones by a balancing act of LIM kinase and Slingshot phosphatase on ADF/cofilin. J. Cell Biol. 178 107–119

Article  CAS  PubMed  PubMed Central  Google Scholar 

Wennagel D, Braz BY, Capizzi M, et al. 2022 Huntingtin coordinates dendritic spine morphology and function through cofilin-mediated control of the actin cytoskeleton. Cell Rep. 40 111261

Article  CAS  PubMed  Google Scholar 

Wiggan O, Bernstein B and Bamburg J 2005 A phosphatase for cofilin to be HAD. Nat. Cell Biol. 7 8–9

Article  CAS  PubMed  Google Scholar 

Zhang R, Chen H, Guo K, et al. 2025 Spatiotemporal expression of Nischarin in developing rat brain mediates neuronal migration via the PAK1/LIMK1/cofilin pathway. Neurosci. Lett. 856–858 138251

Zheng P, Pan C, Zhou C, et al. 2023 Contribution of Nischarin/IRAS in CNS development, injury and diseases. J. Adv. Res. 54 43–57

Article  CAS  PubMed  PubMed Central  Google Scholar